Influence of branched-chain amino acid composition of culture media on the synthesis of plasma proteins by serum-free cultured rat hepatocytes

1989 ◽  
Vol 25 (4) ◽  
pp. 358-364 ◽  
Author(s):  
Angel Montoya ◽  
Maria J. Gómez-Lechón ◽  
Jose V. Castell
2011 ◽  
Vol 46 (7) ◽  
pp. 1423-1429 ◽  
Author(s):  
Zizhuo Xing ◽  
Brian Kenty ◽  
Inna Koyrakh ◽  
Michael Borys ◽  
Shih-Hsie Pan ◽  
...  

Author(s):  
Yu. E. Razvodovsky ◽  
V. Yu. Smirnov ◽  
I. N. Semenenya

The effects of complex compositions, containing branched-chain amino acids (BCAA), taurine and tryptophan, on the pool of free amino acids in the liver of rats were studied under the conditions of subchronic alcohol intoxication (SHAI). It was established that SHAI led to the decreased levels of treonine, lysine, oxyproline, arginine, b-alanine, as well as the depletion of the pool of irreplaceable amino acids in the liver of rats. Administration of the composition of BCAA and taurine was found to normalize the ratio of replaceable irreplaceable amino acids, the ratio of glycogenic and ketogenic amino acids, to activate the reaction of nitrogen utilization, and to increase Fisher’s index. The effects of the composition, containing BCAA, taurine and tryptophan, were similar to those of amino acid composition that did not contain tryptophan.


2014 ◽  
Author(s):  
Alexandra Jayne Kermack ◽  
Ying Cheong ◽  
Nick Brook ◽  
Nick Macklon ◽  
Franchesca D Houghton

Sign in / Sign up

Export Citation Format

Share Document