In vitro cultivation of human renal cell cancer

In Vitro ◽  
1978 ◽  
Vol 14 (9) ◽  
pp. 779-786 ◽  
Author(s):  
R. D. Williams ◽  
A. Y. Elliott ◽  
N. Stein ◽  
E. E. Fraley
Keyword(s):  
Renal Cell Cancer ◽  
Renal Cell ◽  
Cell Cancer ◽  
In Vitro Cultivation ◽  
Human Renal Cell Cancer

In vitro cultivation of human renal cell cancer

In Vitro ◽  
1976 ◽  
Vol 12 (9) ◽  
pp. 623-627 ◽  
Author(s):  
R. D. Williams ◽  
A. Y. Elliott ◽  
N. Stein ◽  
E. E. Fraley
Keyword(s):  
Renal Cell Cancer ◽  
Renal Cell ◽  
Cell Cancer ◽  
In Vitro Cultivation ◽  
Human Renal Cell Cancer

Sustained NRF2 activation in hereditary leiomyomatosis and renal cell cancer (HLRCC) and in hereditary tyrosinemia type 1 (HT1)

2015 ◽  
Vol 43 (4) ◽  
pp. 650-656 ◽  
Author(s):  
Ivraj Singh Sandhu ◽  
Nicholas James Maksim ◽  
Eva Alice Amouzougan ◽  
Bryce Wilson Gallion ◽  
Anthony L.J. Raviele ◽  
...  
Keyword(s):  
Renal Cell Cancer ◽  
Renal Cell ◽  
Cell Cancer ◽  
Hereditary Syndromes ◽  
Nrf2 Activation ◽  
Tyrosinemia Type 1 ◽  
Hereditary Tyrosinemia ◽  
Hereditary Leiomyomatosis

The nuclear erythroid 2-like 2 transcription factor (NRF2), is a major regulator of cellular redox balance. Although NRF2 activation is generally regarded as beneficial to human health, recent studies have identified that sustained NRF2 activation is over-represented in many cancers. This raises the question regarding the role of NRF2 activation in the development and progression of those cancers. This review focuses on the mechanisms and the effects of NRF2 activation in two hereditary cancer predisposition syndromes: hereditary leiomyomatosis and renal cell cancer (HLRCC) and hereditary tyrosinemia type 1 (HT1). Because the cancer initiating mutations in these hereditary syndromes are well defined, they offer a unique opportunity to explore the roles of NRF2 activation in the early stages of carcinogenesis. Over the years, a variety of approaches have been utilized to study the biology of HLRCC and HT1. In HLRCC, in vitro studies have demonstrated the importance of NRF2 activation in sustaining cancer cell proliferation. In the mouse model of HT1 however, NRF2 activation seems to protect cells from malignant transformation. In both HT1 and HLRCC, NRF2 activation promotes the clearance of electrophilic metabolites, enabling cells to survive cancer-initiating mutations. Biological insights gained from the hereditary syndromes’ studies may shed light on to the roles of NRF2 activation in sporadic tumours.

Efficacy of Ablative High-Dose-per-Fraction Radiation for Implanted Human Renal Cell Cancer in a Nude Mouse Model

2006 ◽  
Vol 50 (4) ◽  
pp. 795-800 ◽  
Author(s):  
Lance Walsh ◽  
Jennifer L. Stanfield ◽  
L. Chinsoo Cho ◽  
Cheng-hui Chang ◽  
Kenneth Forster ◽  
...  
Keyword(s):  
Mouse Model ◽  
Nude Mouse ◽  
Renal Cell Cancer ◽  
Renal Cell ◽  
Cell Cancer ◽  
High Dose ◽  
Nude Mouse Model ◽  
Human Renal Cell Cancer ◽  
Dose Per Fraction

The Effects of Interleukin-6 on Tumor-Infiltrating Lymphocytes Derived from Human Renal Cell Cancer

1991 ◽  
Vol 145 (3) ◽  
pp. 663-667 ◽  
Author(s):  
Tchun Y. Lee ◽  
Alec S. Koo ◽  
Christian Peyret ◽  
Tomoyuki Shimabukuro ◽  
Jean B. Dekernion ◽  
...  
Keyword(s):  
Renal Cell Cancer ◽  
Interleukin 6 ◽  
Renal Cell ◽  
Cell Cancer ◽  
Tumor Infiltrating Lymphocytes ◽  
Human Renal Cell Cancer ◽  
Infiltrating Lymphocytes

scholarly journals Chemosensitization of Human Renal Cell Cancer Using Antisense Oligonucleotides Targeting the Antiapoptotic Gene Clusterin

Neoplasia ◽  
2001 ◽  
Vol 3 (4) ◽  
pp. 360-367 ◽  
Author(s):  
Tobias Zellweger ◽  
Hideaki Miyake ◽  
Laura V. July ◽  
Majid Akbari ◽  
Satoshi Kiyama ◽  
...  
Keyword(s):  
Renal Cell Cancer ◽  
Renal Cell ◽  
Antisense Oligonucleotides ◽  
Cell Cancer ◽  
Antiapoptotic Gene ◽  
Human Renal Cell Cancer

scholarly journals Polymorphisms of the CYP1B1 Gene as Risk Factors for Human Renal Cell Cancer

2004 ◽  
Vol 10 (6) ◽  
pp. 2015-2019 ◽  
Author(s):  
Masahiro Sasaki ◽  
Yuichiro Tanaka ◽  
Steven T. Okino ◽  
Mitsuharu Nomoto ◽  
Suguru Yonezawa ◽  
...  
Keyword(s):  
Risk Factors ◽  
Renal Cell Cancer ◽  
Renal Cell ◽  
Cell Cancer ◽  
Cyp1b1 Gene ◽  
Human Renal Cell Cancer

Indirubin-3‘-Monoxime, an Inhibitor of Cyclin Dependent Kinases, Induces Growth Inhibition and Apoptosis in Renal Cell Cancer in vitro

2007 ◽  
Vol 1 (1) ◽  
pp. 18-23
Author(s):  
F.G.E. Perabo ◽  
G. Landwehrs ◽  
C. Frössler ◽  
D.H. Schmidt ◽  
A. Wirger ◽  
...  
Keyword(s):  
Growth Inhibition ◽  
Renal Cell Cancer ◽  
Renal Cell ◽  
Cell Cancer ◽  
Cyclin Dependent Kinases
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