Evaluation of the fibrinolytic system in full-term neonates

1995 ◽  
Vol 25 (3) ◽  
pp. 149-152 ◽  
Author(s):  
A. Pinacho ◽  
J. A. Páramo ◽  
M. Ezcurdia ◽  
E. Rocha
Keyword(s):  
Full Term ◽  
Fibrinolytic System ◽  
Term Neonates

Assessment of serum levels of vitamin B12 in full term neonates with indirect hyperbilirubinemia

2019 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Gamal Mohamed ◽  
Reem Abdel-Salam ◽  
Rabie Mortada
Keyword(s):  
Vitamin B12 ◽  
Serum Levels ◽  
Full Term ◽  
Term Neonates

Cord Blood Alkaline Phosphatase as a predictor of Neonatal Jaundice in full term neonates

2020 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Samah Esmail ◽  
Ali Abdo ◽  
Sherief Elgebaly ◽  
Marwa Mostafa
Keyword(s):  
Alkaline Phosphatase ◽  
Cord Blood ◽  
Neonatal Jaundice ◽  
Full Term ◽  
Term Neonates

scholarly journals Sufentanil Disposition and Pharmacokinetic Model-Based Dosage Regimen for Sufentanil in Ventilated Full-Term Neonates

Pharmacology ◽  
2021 ◽  
pp. 1-6
Author(s):  
Pavla Pokorná ◽  
Martin Šíma ◽  
Birgit Koch ◽  
Dick Tibboel ◽  
Ondřej Slanař
Keyword(s):  
Linear Regression ◽  
Dosage Regimen ◽  
Regression Models ◽  
Drug Disposition ◽  
Prospective Trial ◽  
Full Term ◽  
Pharmacokinetic Parameters ◽  
Therapeutic Drug ◽  
Linear Regression Models ◽  
Term Neonates

<b><i>Introduction:</i></b> Sufentanil is a potent synthetic opioid used for analgesia in neonates; however, data concerning drug disposition of sufentanil and dosage regimen are sparse in this population. Therefore, the aim of the study was to explore sufentanil disposition and to propose optimal loading and maintenance doses of sufentanil in ventilated full-term neonates. <b><i>Methods:</i></b> Individual sufentanil pharmacokinetic parameters were calculated based on therapeutic drug monitoring data using a 2-compartmental model. Linear regression models were used to explore the covariates. <b><i>Results:</i></b> The median (IQR) central volume of distribution (Vd<sub>c</sub>) and clearance (CL) for sufentanil were 4.7 (4.1–5.4) L/kg and 0.651 (0.433–0.751) L/h/kg, respectively. Linear regression models showed relationship between Vd<sub>c</sub> (L) and GA (<i>r</i><sup>2</sup> = 0.3436; <i>p</i> = 0.0452) as well as BW (<i>r</i><sup>2</sup> = 0.4019; <i>p</i> = 0.0268). Median optimal sufentanil LD and MD were 2.13 (95% CI: 1.78–2.48) μg/kg and 0.29 (95% CI: 0.22–0.37) μg/kg/h, respectively. Median daily COMFORT-B (IQR) scores ranged from 6 to 23 while no significant relationship between pharmacokinetic parameters and COMFORT-B scores was found. <b><i>Discussion/Conclusion:</i></b> Body weight and gestational age were found as weak covariates for sufentanil distribution, and the dosage regimen was developed for a prospective trial.

The Hemodynamically Significant Ductus Arteriosus in Critically Ill Full-Term Neonates

Neonatology ◽  
2006 ◽  
Vol 91 (4) ◽  
pp. 260-265 ◽  
Author(s):  
Linh G. Ly ◽  
Judith Hawes ◽  
Hilary E. Whyte ◽  
Lilian S. Teixeira ◽  
Patrick J. McNamara
Keyword(s):  
Critically Ill ◽  
Ductus Arteriosus ◽  
Full Term ◽  
Term Neonates

Bifidobacterium longum and Bifidobacterium breve isolates from preterm and full term neonates: Comparison of cell surface properties

Anaerobe ◽  
2014 ◽  
Vol 28 ◽  
pp. 212-215 ◽  
Author(s):  
Valérie Andriantsoanirina ◽  
Anne-Claire Teolis ◽  
Liu Xin Xin ◽  
Marie Jose Butel ◽  
Julio Aires
Keyword(s):  
Cell Surface ◽  
Surface Properties ◽  
Bifidobacterium Longum ◽  
Full Term ◽  
Term Neonates ◽  
Bifidobacterium Breve ◽  
Cell Surface Properties

Magnetic Resonance Imaging Evaluation of Neonates With Retinal Hemorrhages

PEDIATRICS ◽  
1992 ◽  
Vol 89 (2) ◽  
pp. 332-333
Author(s):  
WILBUR L. SMITH ◽  
RANDELL C. ALEXANDER ◽  
G. FRANK JUDISCH ◽  
YUTAKA SATO ◽  
SIMON C. S. KAO
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Abusive Head Trauma ◽  
Full Term ◽  
Resonance Imaging ◽  
Retinal Hemorrhages ◽  
Imaging Evaluation ◽  
Term Neonates ◽  
Magnetic Resonance Imaging Evaluation ◽  
A Prospective Study

Retinal hemorrhages occur frequently in association with abusive head trauma.1 The injuries are venous [See table in the PDF] in origin and, as such, are similar to the retinal hemorrhages which frequently occur in full-term neonates after vaginal delivery. Because retinal hemorrhages in child abuse frequently are associated with intracranial bleeding, we questioned the possibility of a relationship between parturitional retinal hemorrhages and concurrent intracranial injuries. To answer this question we designed a prospective study in which we performed magnetic resonance imaging on 10 randomly selected full-term neonates in whom the presence of retinal hemorrhages was confirmed on fundascopic examination by a pediatric ophthalmologist.

Genetic polymorphisms of IL-6-174 and IL-10-1082 in full term neonates with late onset blood stream infections

2015 ◽  
Vol 04 (04) ◽  
pp. 357-365 ◽  
Author(s):  
Mohamed El-Naggar ◽  
Ghada El-Nady ◽  
Rawia Badr ◽  
Medhat El-Daker ◽  
Hesham Abdel-Hady
Keyword(s):  
Genetic Polymorphisms ◽  
Late Onset ◽  
Blood Stream ◽  
Full Term ◽  
Blood Stream Infections ◽  
Term Neonates

scholarly journals Incidence of Acute Renal Failure in Full Term Neonates with Birth Asphyxia

2019 ◽  
Vol 4 (1) ◽  
pp. 671-674
Author(s):  
Chandra Bhushan Jha ◽  
Akhil Tamrakar
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Serum Creatinine ◽  
Renal Injury ◽  
Urine Output ◽  
Birth Asphyxia ◽  
Full Term ◽  
Acute Renal Injury ◽  
Term Neonates ◽  
Oliguric Renal Failure

Introduction: Birth asphyxia is an eventuality having far reaching consequences in the neonatal period. Hypoxia and ischemia can cause damage to almost every tissue and organ in the body and various target organs involved. Renal insult is a recognized complication of birth asphyxia and carries a poor prognosis. Timely detection of renal dysfunction and appropriate management may favorably alter the prognosis in many neonates with birth asphyxia. Objective: The present study was done to find out the incidence of acute renal failure in the full term neonates with birth asphyxia. Methodology: A cross sectional study was conducted at Birat Medical College Teaching Hospital, Morang, Nepal from 1st September 2017 to 28th February 2018. Fifty full term neonates born with Apgar score of <6 at 5 minutes and fulfilling inclusion criteria were enrolled in the study. Asphyxiated neonates having Serum creatinine >1.5gm/dl or urine output<1ml/kg/hr were labeled as cases of Acute Renal Failure. Blood sample for serum creatinine was collected at 24hrs, 48 hrs and 72 hrs of life. Results A total of 50 term asphyxiated neonates were enrolled in the present study. Among them 54% and 46% were males and females respectively with male to female ratio of 1.2:1. In the present study 62% of cases developed acute renal failure in either of the first three days of life with mean urine output 1.02±0.27ml/kg/hr and mean serum creatinine of 1.49±0.32 mg/dL. The incidence of oliguric renal failure was 52% and non oliguric renal failure was 48%.The association between serum creatinine and urine output was statistically significant. Conclusion: In the present study birth asphyxia has been an important cause of neonatal acute renal injury, revealing 31 (62%) cases. Monitoring urine output and serum creatinine has helped in detecting the asphyxiated neonates with acute renal injury in the early stage.

Sign in / Sign up

Export Citation Format

Share Document