scholarly journals A model for compound action potentials and currents in a nerve bundle II: A sensitivity analysis of model parameters for the forward and inverse calculations

1991 ◽  
Vol 19 (3) ◽  
pp. 339-339 ◽  
Author(s):  
R. S. Wijesinghe ◽  
J. P. Wikswo
Keyword(s):  
Sensitivity Analysis ◽  
Action Potentials ◽  
Model Parameters ◽  
Nerve Bundle ◽  
Compound Action Potentials ◽  
Compound Action

Effects of GABA, THIP, and potassium on excitability of myelinated axons of isolated amphibian spinal roots

1989 ◽  
Vol 67 (6) ◽  
pp. 682-685 ◽  
Author(s):  
S. Liske ◽  
M. E. Morris
Keyword(s):  
Action Potentials ◽  
Dorsal Root ◽  
Ventral Root ◽  
Aminobutyric Acid ◽  
Nerve Bundle ◽  
Myelinated Axons ◽  
Root Sheath ◽  
Compound Action Potentials ◽  
Spinal Roots ◽  
Compound Action

The effects of direct applications of GABA (γ-aminobutyric acid) and the GABAA agonist, THIP (4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol) on the excitability of myelinated axons of individual dorsal and ventral spinal roots (lumbar VI and (or) VII) of the isolated bullfrog peripheral nerve are reported. Increases evoked by the GABA agonists (0.01–10 mM) in the amplitude of half-maximal A-fiber compound action potentials indicate the presence of depolarizing responses with apparently greater localization to the dorsal roots, and a sensitivity to GABA twofold greater than that for THIP. The changes evoked by GABA and THIP, as well as potassium have components that closely resemble those of sensory and motor fibers in the more distal, desheathed nerve bundle but are smaller and delayed, differences attributable to a closely attached root sheath that acts as a diffusion barrier. These results confirm the likely existence of GABAA receptors on both dorsal and ventral spinal roots.Key words: GABAA receptors, dorsal root fibers, ventral root fibers, depolarization, hyperpolarization.

Stretch of mammalian nerve in vitro: Effect on compound action potentials

2000 ◽  
Vol 5 (4) ◽  
pp. 227-235 ◽  
Author(s):  
Sidney Ochs ◽  
Rahman Pourmand ◽  
Kenan Si ◽  
Richard N. Friedman
Keyword(s):  
Action Potentials ◽  
Compound Action Potentials ◽  
Vitro Effect ◽  
Mammalian Nerve ◽  
Compound Action

scholarly journals Site of cochlear stimulation and its effect on electrically evoked compound action potentials using the MED-EL standard electrode array

2009 ◽  
Vol 8 (1) ◽  
pp. 40 ◽  
Author(s):  
Stefan Brill ◽  
Joachim Müller ◽  
Rudolf Hagen ◽  
Alexander Möltner ◽  
Steffi-Johanna Brockmeier ◽  
...  
Keyword(s):  
Action Potentials ◽  
Electrode Array ◽  
Compound Action Potentials ◽  
Compound Action

Using Evoked Compound Action Potentials to Assess Activation of Electrodes and Predict C-Levels in the Tempo+ Cochlear Implant Speech Processor

2010 ◽  
Vol 31 (1) ◽  
pp. 134-145 ◽  
Author(s):  
Isaac Alvarez ◽  
Angel de la Torre ◽  
Manuel Sainz ◽  
Cristina Roldán ◽  
Hansjoerg Schoesser ◽  
...  
Keyword(s):  
Cochlear Implant ◽  
Action Potentials ◽  
Speech Processor ◽  
Compound Action Potentials ◽  
Compound Action

Synaptic transmission in the chronically decentralized middle cervical and stellate ganglia of the dog

1983 ◽  
Vol 61 (10) ◽  
pp. 1149-1155 ◽  
Author(s):  
J. A. Armour
Keyword(s):  
Central Nervous System ◽  
Action Potentials ◽  
Autonomic Nerves ◽  
Autonomic Ganglia ◽  
Afferent Nerves ◽  
Stellate Ganglia ◽  
Compound Action Potentials ◽  
The Central Nervous System ◽  
Compound Action ◽  
Stimulation Of

Afferent stimulation of one thoracic cardiopulmonary nerve generated compound action potentials in the efferent axons of other ipsilateral cardiopulmonary nerves in dogs, 14 days after their thoracic autonomic ganglia had been decentralized. The compound action potentials were influenced by the frequency of activation and (in 5 of 12 dogs) by pharmacological autonomic blocking agents (hexamethonium, atropine, phentolamine, and propranolol). Moreover, they were abolished transiently when chymotrypsin was injected locally into the ganglia, and extendedly when manganese was injected. Thus, synapses that can be activated by stimulation of afferent nerves exist in chronically decentralized thoracic autonomic nerves and ganglia. It is proposed that regulation of the heart and lungs occurs in part via thoracic autonomic neural elements independent of the central nervous system.

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