Synthesis and characterization of new diam(M)ine platinum(IV) complexes containing lipophilic carboxylate ligands

1995 ◽  
Vol 121 (S1) ◽  
pp. A50-A50
Author(s):  
M. Galanski ◽  
B. K. Keppler
Keyword(s):  
Synthesis And Characterization ◽  
Carboxylate Ligands

Synthesis and Characterization of New Hydridoiridium Complexes Containing Carboxylate Ligands

1994 ◽  
Vol 33 (16) ◽  
pp. 3473-3480 ◽  
Author(s):  
Miguel A. Esteruelas ◽  
Maria P. Garcia ◽  
Fernando J. Lahoz ◽  
Marta Martin ◽  
Javier Modrego ◽  
...  
Keyword(s):  
Synthesis And Characterization ◽  
Carboxylate Ligands

scholarly journals Synthesis and Characterization of New Ethylenediamine Platinum(IV) Complexes Containing Lipophilic Carboxylate Ligands

1995 ◽  
Vol 2 (1) ◽  
pp. 57-63 ◽  
Author(s):  
M. Galanski ◽  
B. K. Keppler
Keyword(s):  
Axial Position ◽  
Synthesis And Characterization ◽  
Equatorial Position ◽  
Spectroscopic Techniques ◽  
Acyl Halide ◽  
Carboxylate Ligands ◽  
New Class ◽  
Carboxylate Groups ◽  
Long Chain

A series of new ethylenediamine (en) platinum(IV) complexes of the type Pt(IV)enX2A2 , with X2 = cyclobutane-1,1-dicarboxylato (CBDCA), dichloro or bis(decanoato) and A = acetato, dodecanoato, tetradecanoato, hexadecanoato, octadecanoato, adamantanecarboxylato (Ad) or 3α, 12α -diformoxy-5β-cholato (DFCA) were synthesized and characterized by elemental analysis, infrared and NMR (H1 and C13) spectroscopic techniques. Previous platinum(IV) compounds were usually restricted to trans-dihydroxo or trans-dichloro platinum(IV) complexes. Recently trans-dicarboxylato platinum(IV) complexes with mainly acetate, trifluoracetate or short-chain carboxylate groups (<11 carbons) in the axial position have been described in the literature[1,2,3]. In this paper we report on the synthesis and characterization of a new class of ethylenediamine platinum(IV) compounds that have high lipophilic long-chain carboxylate ligands either in the axial or equatorial position. The platinum(IV) compounds with the lipophilic trans-carboxylate ligands in the axial position were prepared by acylation of the trans-dihydroxo platinum(IV) species using an acyl halide in the presence of pyridine. In contrast to previous publications[1] the yields were excellent (up to 94%!).

Synthesis and Characterization of Carboxylic Acids Bearing Poly(ethylene glycol) Chains

Synlett ◽  
2017 ◽  
Vol 29 (05) ◽  
pp. 556-559 ◽  
Author(s):  
Tetsuaki Fujihara ◽  
Yasushi Tsuji ◽  
Motoi Satou ◽  
Jun Terao
Keyword(s):  
Carboxylic Acid ◽  
Ethylene Glycol ◽  
Carboxylic Acids ◽  
Aerobic Oxidation ◽  
Synthesis And Characterization ◽  
Poly Ethylene Glycol ◽  
Carboxylate Ligands ◽  
Poly Ethylene

Carboxylic acids 1a and 1b bearing three poly(ethylene glycol) (PEG) chains and carboxylic acid 1c bearing one PEG chain were designed and synthesized. The carboxylic acids 1a–c were fully characterized by NMR and ESI-HRMS analyses. In a Pd-catalyzed aerobic oxidation of 1-phenylethanol, 1a and 1b worked well as carboxylate ligands.

Synthesis and Characterization of Platinum(IV) Anticancer Drugs with Functionalized Aromatic Carboxylate Ligands:  Influence of the Ligands on Drug Efficacies and Uptake

2005 ◽  
Vol 48 (25) ◽  
pp. 8060-8069 ◽  
Author(s):  
Wee Han Ang ◽  
Sébastien Pilet ◽  
Rosario Scopelliti ◽  
François Bussy ◽  
Lucienne Juillerat-Jeanneret ◽  
...  
Keyword(s):  
Anticancer Drugs ◽  
Synthesis And Characterization ◽  
Carboxylate Ligands ◽  
Aromatic Carboxylate

Synthesis and Characterization of a [Mn 12 O 12 (O 2 CR) 16 (H 2 O) 4 ] Complex Bearing Paramagnetic Carboxylate Ligands. Use of a Modified Acid Replacement Synthetic Approach

2003 ◽  
Vol 134 (2) ◽  
pp. 265-276 ◽  
Author(s):  
Philippe Gerbier ◽  
Daniel Ruiz-Molina ◽  
Neus Domingo ◽  
David B. Amabilino ◽  
Jos� Vidal-Gancedo ◽  
...  
Keyword(s):  
Synthesis And Characterization ◽  
Synthetic Approach ◽  
Carboxylate Ligands

Synthesis and characterization of Cu(II) paddlewheel complexes possessing fluorinated carboxylate ligands

2009 ◽  
Vol 130 (2) ◽  
pp. 197-203 ◽  
Author(s):  
Alexander N. Wein ◽  
Rebekah Cordeiro ◽  
Natalie Owens ◽  
Hillary Olivier ◽  
Kenneth I. Hardcastle ◽  
...  
Keyword(s):  
Synthesis And Characterization ◽  
Carboxylate Ligands ◽  
Paddlewheel Complexes

Synthesis and Characterization of Cyclometalated NHC Platinum Complexes with Chelating Carboxylate Ligands

2019 ◽  
Vol 2019 (17) ◽  
pp. 2284-2290 ◽  
Author(s):  
Martin Zábranský ◽  
Johannes Soellner ◽  
Filip Horký ◽  
Ivana Císařová ◽  
Petr Štěpnička ◽  
...  
Keyword(s):  
Platinum Complexes ◽  
Synthesis And Characterization ◽  
Carboxylate Ligands
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