Effect of a high protein intake on acid-base balance in adult rats

1989 ◽  
Vol 44 (5) ◽  
pp. 339-342 ◽  
Author(s):  
G. Trilok ◽  
H. H. Draper
2006 ◽  
Vol 38 (S36) ◽  
pp. 648-653 ◽  
Author(s):  
M. CONNYSSON ◽  
S. MUHONEN ◽  
J. E. LINDBERG ◽  
B. ESSÉN-GUSTAVSSON ◽  
G. NYMAN ◽  
...  

2018 ◽  
Vol 3 (90) ◽  
Author(s):  
Marius Baranauskas ◽  
Linas Tubelis ◽  
Rimantas Stukas ◽  
Edmundas Švedas ◽  
Laimutė Samsonienė ◽  
...  

Research  background  and  hypothesis.  Unbalanced  nutritional  status,  incorrect  qualitative  and  quantitative content of nutritional and bioactive substances (nutrition value) for athletes in strength and speed sports can have a negative impact on acid-base homeostasis and physical working performance. Hypothesis – there is a dietary acid-base balance in the Lithuanian Olympic basketball team players’ food rations. Research aim was to assess dietary acid-base balance in Lithuanian high-performance basketball players during the training mezzo-cycles designed for strength training.Research methods. In the general preparation period, Lithuanian Olympic Team basketball players (n = 52), aged 18.0 ± 1.9 years, training 197.9 ± 58.7 min a day, 6 days a week on average, were tested. Body composition  analysis  of  athletes  was  performed  using  bioelectrical  impedance  analysis  (BIA)  method. Applying  the  survey  method we investigated and assessed the nutritional status of basketball players, possible effect of their dietary intake  on potential renal acid load (PRAL) and net endogenous acid production (NEAP).Research results. The dietary PRAL of more than half (67.3%) of subjects was positive (8.5 ± 49.0 mEq/day). Basketball players’ protein intake was positively related to dietary PRAL (r = 0.408, p = 0.003). Protein intake of 20.5% of male basketball players on average was 2.6 ± 0.7 g/kg body weight, and their dietary PRAL was 75.5 ± 22.8 mEq/day, NEAP – 128.5 ± 23.7 mEq/day. Discussion and conclusions. If high-protein diet (protein intake meets 1.8–2.0 g/kg BW) is followed, basketball players’ nutritional habits should be changed. Athletes are recommended to consume significantly more fresh fruits and vegetables and/or enrich the normal diet by sodium bicarbonate and/or beta-alanine dietary supplements.Keywords: basketball, acid-base balance, renal acid overload.


1990 ◽  
Vol 258 (6) ◽  
pp. F1528-F1537 ◽  
Author(s):  
V. A. Murphy ◽  
C. E. Johanson

Basolateral Na(+)-H+ exchange was analyzed with an in vivo model of choroid plexus (CP) epithelium in nephrectomized adult rats anesthetized with ketamine. Acid-base balance in blood was altered for 1 h over a pH continuum of 7.19 to 7.53 by equimolar intraperitoneal injections of HCl, NH4Cl, NaCl, or NaHCO3. Compartmental analysis enabled determination of CP intracellular pH (pHi) [dimethadione (DMO) method] and the choroid cellular concentration of 23Na (stable) and 22Na (tracer). HCl acidosis reduced the outwardly directed transmembrane basolateral H+ gradient, lowered the [23Na]i by 25%, and decreased the influx coefficient (Kin) for 22Na from blood into CP parenchyma (by 45% from 0.211 to 0.117 ml.g-1.h-1) and into cerebrospinal fluid (CSF) (by 43%, from 0.897 to 0.516). Compared with acid-loaded rats (HCl or NH4Cl), the NaHCO3-alkalotic animals had significantly enhanced uptake of 22Na into the CP-CSF system. This pH-dependent transport of Na+ from blood to CP was abolished by pretreatment with amiloride, an inhibitor of Na(+)-H+ exchange. Except in severe acidosis (HCl), the choroid cell pHi (7.05 +/- 0.02 in NaCl controls) and [HCO3-] (11-12 mM) remained stable in the face of acidemic and alkalemic challenges. With respect to reaction of the blood-CSF barrier to plasma acid-base perturbations, the responses of the fourth ventricle plexus pHi, [Na+]i, and 22Na uptake were similar to corresponding ones in lateral plexuses. We conclude that in the choroidal epithelium there is a Na(+)-H+ exchange activity capable of modulating Na+ flux into the CSF by approximately 50% as arterial pH is varied from 7.2 to 7.5.


2002 ◽  
Vol 40 (2) ◽  
pp. 265-274 ◽  
Author(s):  
Shalini T. Reddy ◽  
Chia-Ying Wang ◽  
Khashayar Sakhaee ◽  
Linda Brinkley ◽  
Charles Y.C. Pak

2003 ◽  
Vol 58 (2) ◽  
pp. 113-114
Author(s):  
Shalini T. Reddy ◽  
Chia-Ying Wang ◽  
Khashayar Sakhaee ◽  
Linda Brinkley ◽  
Charles Y. C. Pak

2014 ◽  
Vol 84 (3-4) ◽  
pp. 0206-0217 ◽  
Author(s):  
Seyedeh-Elaheh Shariati-Bafghi ◽  
Elaheh Nosrat-Mirshekarlou ◽  
Mohsen Karamati ◽  
Bahram Rashidkhani

Findings of studies on the link between dietary acid-base balance and bone mass are relatively mixed. We examined the association between dietary acid-base balance and bone mineral density (BMD) in a sample of Iranian women, hypothesizing that a higher dietary acidity would be inversely associated with BMD, even when dietary calcium intake is adequate. In this cross-sectional study, lumbar spine and femoral neck BMDs of 151 postmenopausal women aged 50 - 85 years were measured using dual-energy x-ray absorptiometry. Dietary intakes were assessed using a validated food frequency questionnaire. Renal net acid excretion (RNAE), an estimate of acid-base balance, was then calculated indirectly from the diet using the formulae of Remer (based on dietary intakes of protein, phosphorus, potassium, and magnesium; RNAERemer) and Frassetto (based on dietary intakes of protein and potassium; RNAEFrassetto), and was energy adjusted by the residual method. After adjusting for potential confounders, multivariable adjusted means of the lumbar spine BMD of women in the highest tertiles of RNAERemer and RNAEFrassetto were significantly lower than those in the lowest tertiles (for RNAERemer: mean difference -0.084 g/cm2; P=0.007 and for RNAEFrassetto: mean difference - 0.088 g/cm2; P=0.004). Similar results were observed in a subgroup analysis of subjects with dietary calcium intake of >800 mg/day. In conclusion, a higher RNAE (i. e. more dietary acidity), which is associated with greater intake of acid-generating foods and lower intake of alkali-generating foods, may be involved in deteriorating the bone health of postmenopausal Iranian women, even in the context of adequate dietary calcium intake.


2016 ◽  
Vol 24 (3) ◽  
pp. 116-121
Author(s):  
김지용 ◽  
남상욱 ◽  
김영미 ◽  
이윤진 ◽  
이훈상 ◽  
...  

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