The effect of metabolic acidosis on serum apolipoprotein A I and apolipoprotein B levels in children with chronic renal failure

1997 ◽  
Vol 29 (5) ◽  
pp. 603-607
Author(s):  
Z. Bircan ◽  
A. Kaplan ◽  
M. Soran ◽  
M. Söker ◽  
M. Kervancioĝlu ◽  
...  
Keyword(s):  
Renal Failure ◽  
Metabolic Acidosis ◽  
Chronic Renal Failure ◽  
Apolipoprotein B ◽  
Apolipoprotein A

scholarly journals Acetazolamide Intoxication in an Elderly Patient with Diabetes and Chronic Renal Failure after Cataract Surgery

2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Juliana Maria Kerber ◽  
Juliana Dias de Mello ◽  
Karolinny Borinelli de Aquino Moura ◽  
Gustavo Cardoso da Silva ◽  
Iuri Christmann Wawrzeniak ◽  
...  
Keyword(s):  
Elderly Patient ◽  
Renal Failure ◽  
Metabolic Acidosis ◽  
Chronic Renal Failure ◽  
Clinical Symptoms ◽  
Open Angle Glaucoma ◽  
Rare Complication ◽  
Severe Metabolic Acidosis ◽  
Ophthalmic Surgery ◽  
Drug Concentrations

Carbonic anhydrase inhibitors, such as acetazolamide, are widely used in the treatment of open-angle glaucoma. Severe metabolic acidosis is a rare complication of acetazolamide use, and life-threatening acidosis occurs most commonly in elderly patients, in patients with advanced renal failure, and in patients with diabetes. We describe an unusual case of an elderly patient with diabetic nephropathy and chronic renal failure who presented to the emergency department with severe metabolic acidosis and coma after exposure to high doses of acetazolamide in the postoperative period of ophthalmic surgery. As symptoms of acetazolamide intoxication and uremia are similar, high suspicion is required to detect excessive plasma drug concentrations and intoxication in patients presenting with concomitant uremia. Clinical symptoms are potentially reversible with prompt diagnosis and treatment, including supportive treatment, bicarbonate therapy, and renal replacement therapy. Hemodialysis is particularly helpful in the management of acetazolamide overdose as the medication is dialyzable.

Growth hormone stimulation tests in chronic renal failure with metabolic acidosis

2007 ◽  
Vol 40 (1) ◽  
pp. 70-72 ◽  
Author(s):  
ZELÂL BIRCAN ◽  
MEHMET KERVANCIOǦL̈ ◽  
MUSTAFA SORAN ◽  
IDRIS YILDIRIM
Keyword(s):  
Growth Hormone ◽  
Renal Failure ◽  
Metabolic Acidosis ◽  
Chronic Renal Failure ◽  
Hormone Stimulation ◽  
Stimulation Tests

Changes in serum leptin levels in chronic renal failure patients with metabolic acidosis

2001 ◽  
Vol 11 (4) ◽  
pp. 207-211 ◽  
Author(s):  
Falei Zheng ◽  
Xinxia Qiu ◽  
Suyan Yin ◽  
Yan Li
Keyword(s):  
Renal Failure ◽  
Metabolic Acidosis ◽  
Chronic Renal Failure ◽  
Serum Leptin

Metabolic Acidosis Does Not Contribute to Chronic Renal Injury in the Rat

1995 ◽  
Vol 89 (6) ◽  
pp. 643-650 ◽  
Author(s):  
D. Throssell ◽  
J. Brown ◽  
K. P. G. Harris ◽  
J. Walls
Keyword(s):  
Renal Failure ◽  
Metabolic Acidosis ◽  
Chronic Renal Failure ◽  
Glomerular Filtration ◽  
Disease Progression ◽  
Renal Injury ◽  
Heart Weight ◽  
Normal Kidney ◽  
Renal Growth ◽  
Remnant Kidney

1. Metabolic acidosis invariably accompanies chronic renal failure, and short periods of metabolic acidosis cause renal growth and proteinuria in normal rats. Rates of ammoniagenesis are increased in chronic renal failure, and it has been suggested that this contributes to disease progression. This study assessed (i) whether prolonged acidosis causes chronic renal injury in the normal kidney and (ii) whether abrogation of acidosis slows disease progression in the remnant kidney. 2. Metabolic acidosis was induced in normal rats by dietary hydrochloric acid. Urinary excretion of total protein, lysozyme and albumin increased, peaking at week 8 but returning to baseline by week 14. At killing after 14 weeks, kidney weights, glomerular filtration rates and serum creatinine were the same in both groups, but kidney/body weight and kidney/heart weight ratios were greater in the acidotic group. All kidneys were normal by light microscopy. 3. Rats subjected to five-sixths nephrectomy were given sufficient dietary bicarbonate to abolish uraemic acidosis, and their outcome was compared with that of non-alkalinized remnants (controls). Proteinuria, glomerular filtration rates, blood pressure, histological injury and time to the development of terminal uraemia were no better in bicarbonate-supplemented animals than in controls. 4. These data demonstrate that metabolic acidosis neither causes nor exacerbates chronic renal injury. We conclude that the treatment of uraemic acidosis is unlikely to influence disease progression in patients with chronic renal failure.

Evaluation of Apolipoprotein A-I Containing Particles in Chronic Renal Failure Patients Undergoing Hemodialysis

1990 ◽  
Vol 10 (2) ◽  
pp. 171-172 ◽  
Author(s):  
Claude Cachera ◽  
Abdelmajid Kandoussi ◽  
Kodjo Equagoo ◽  
Jean-Charles Fruchart ◽  
Albert Tacquet
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Apolipoprotein A

scholarly journals Alterations of protein metabolism by metabolic acidosis in children with chronic renal failure

2000 ◽  
Vol 58 (1) ◽  
pp. 236-241 ◽  
Author(s):  
Yves Boirie ◽  
Michel Broyer ◽  
Marie France Gagnadoux ◽  
Patrick Niaudet ◽  
Jean-Louis Bresson
Keyword(s):  
Renal Failure ◽  
Metabolic Acidosis ◽  
Chronic Renal Failure ◽  
Protein Metabolism

Serum ionized calcium in dogs with chronic renal failure and metabolic acidosis

2006 ◽  
Vol 35 (4) ◽  
pp. 441-445 ◽  
Author(s):  
Marcia M. Kogika ◽  
Marcio D. Lustoza ◽  
Marcia K. Notomi ◽  
Vera A. B. F. Wirthl ◽  
Regina M. S. Mirandola ◽  
...  
Keyword(s):  
Renal Failure ◽  
Metabolic Acidosis ◽  
Chronic Renal Failure ◽  
Ionized Calcium ◽  
Serum Ionized Calcium
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