Relationship between translocation of long-chain acyl-CoA hydrolase, phosphatidate phosphohydrolase and CTP:Phosphocholine cytidylyltransferase and the synthesis of triglycerides and phosphatidylcholine in rat liver

Lipids ◽  
1992 ◽  
Vol 27 (4) ◽  
pp. 241-247 ◽  
Author(s):  
Daniel Asiedu ◽  
Jon Skorve ◽  
Abraham Demoz ◽  
Nina Willumsen ◽  
Rolf K. Berge
1989 ◽  
Vol 261 (2) ◽  
pp. 595-600 ◽  
Author(s):  
Y Kawashima ◽  
N Uy-Yu ◽  
H Kozuka

Inductions by perfluoro-octanoic acid (PFOA) of hepatomegaly, peroxisomal beta-oxidation, microsomal 1-acylglycerophosphocholine acyltransferase and cytosolic long-chain acyl-CoA hydrolase were compared in liver between male and female rats. Marked inductions of these four parameters were seen concurrently in liver of male rats, whereas the inductions in liver of female rats were far less pronounced. The sex-related difference in the response of rat liver to PFOA was much more marked than that seen with p-chlorophenoxyisobutyric acid (clofibric acid) or 2,2′-(decamethylenedithio)diethanol (tiadenol). Hormonal manipulations revealed that this sex-related difference in the inductions is strongly dependent on sex hormones, namely that testosterone is necessary for the inductions, whereas oestradiol prevented the inductions by PFOA.


1998 ◽  
Vol 248 (3) ◽  
pp. 608-612 ◽  
Author(s):  
Junji Yamada ◽  
Kazutaka Suga ◽  
Takao Furihata ◽  
Mari Kitahara ◽  
Takafumi Watanabe ◽  
...  

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