cDNA Cloning and Genomic Organization of Peroxisome Proliferator-Inducible Long-Chain Acyl-CoA Hydrolase from Rat Liver Cytosol

1998 ◽  
Vol 248 (3) ◽  
pp. 608-612 ◽  
Author(s):  
Junji Yamada ◽  
Kazutaka Suga ◽  
Takao Furihata ◽  
Mari Kitahara ◽  
Takafumi Watanabe ◽  
...  
Keyword(s):  
Cdna Cloning ◽  
Rat Liver ◽  
Genomic Organization ◽  
Peroxisome Proliferator ◽  
Liver Cytosol ◽  
Chain Acyl ◽  
Coa Hydrolase ◽  
Rat Liver Cytosol ◽  
Long Chain

Purification, Molecular Cloning, and Genomic Organization of Human Brain Long-Chain Acyl-CoA Hydrolase

1999 ◽  
Vol 126 (6) ◽  
pp. 1013-1019 ◽  
Author(s):  
J. Yamada ◽  
A. Kurata ◽  
M. Hirata ◽  
T. Taniguchi ◽  
H. Takama ◽  
...  
Keyword(s):  
Human Brain ◽  
Molecular Cloning ◽  
Genomic Organization ◽  
Chain Acyl ◽  
Coa Hydrolase ◽  
Long Chain

scholarly journals Sex-related difference in the inductions by perfluoro-octanoic acid of peroxisomal β-oxidation, microsomal 1-acylglycerophosphocholine acyltransferase and cytosolic long-chain acyl-CoA hydrolase in rat liver

1989 ◽  
Vol 261 (2) ◽  
pp. 595-600 ◽  
Author(s):  
Y Kawashima ◽  
N Uy-Yu ◽  
H Kozuka
Keyword(s):  
Rat Liver ◽  
Octanoic Acid ◽  
Female Rats ◽  
Male Rats ◽  
Beta Oxidation ◽  
Related Difference ◽  
Male And Female Rats ◽  
Chain Acyl ◽  
Coa Hydrolase ◽  
Long Chain

Inductions by perfluoro-octanoic acid (PFOA) of hepatomegaly, peroxisomal beta-oxidation, microsomal 1-acylglycerophosphocholine acyltransferase and cytosolic long-chain acyl-CoA hydrolase were compared in liver between male and female rats. Marked inductions of these four parameters were seen concurrently in liver of male rats, whereas the inductions in liver of female rats were far less pronounced. The sex-related difference in the response of rat liver to PFOA was much more marked than that seen with p-chlorophenoxyisobutyric acid (clofibric acid) or 2,2′-(decamethylenedithio)diethanol (tiadenol). Hormonal manipulations revealed that this sex-related difference in the inductions is strongly dependent on sex hormones, namely that testosterone is necessary for the inductions, whereas oestradiol prevented the inductions by PFOA.

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