Effect of epinephrine on the oxidative desaturation of fatty acids in the rat adrenal gland

Lipids ◽  
1986 ◽  
Vol 21 (6) ◽  
pp. 401-404 ◽  
Author(s):  
Elisabet C. Mandon ◽  
Irma N. T. de Gomez Dumm ◽  
Rodolfo R. Brenner
1976 ◽  
Vol 17 (6) ◽  
pp. 616-621
Author(s):  
I N T de Gómez Dumm ◽  
M J T de Alaniz ◽  
R R Brenner

Endocrinology ◽  
1967 ◽  
Vol 81 (2) ◽  
pp. 179-185 ◽  
Author(s):  
L. MACHO ◽  
MURRAY SAFFRAN
Keyword(s):  

1926 ◽  
Vol 22 (5-6) ◽  
pp. 737
Author(s):  
I. Friedland

Arikhbaev (Vesti. Khir., 1926, book 17-18), having established the normal state of the lipolytic index in 30 people with various diseases and then proceeding to the determination of lipase in the blood of 9 various patients and 1 healthy subject exposed to irritating doses of X-ray rays on the adrenal gland, which caused its hyperfunction, finished his research by observing 5 patients with various forms of surgical tuberculosis, of whom three underwent simultaneous x-rays of the adrenal glands with subcutaneous injections of fish oil neutralized from fatty acids, one - only injections of neutralized fish oil and one - only an operational aid.


1972 ◽  
Vol 50 (3) ◽  
pp. 253-256
Author(s):  
M. Palkovič ◽  
L. Macho

A study of the influence of adrenocorticotropin (ACTH) on various adrenal lipid fractions of intact rats indicated that single and repeated doses (3 or 10 days administration) of ACTH had a lipolytic effect on adrenal fat. A decrease of cholesterol and triglyceride content of the adrenal gland after a single dose of ACTH was observed. However, after 3 days injection of ACTH, only the cholesterol concentration diminished. The triglyceride content was the same as that in saline-injected control animals. On the other hand, a significant increase in triglycerides was noted in adrenal gland after 10 days of ACTH injections. No substantial changes in unesterified fatty acids and phospholipids were noted in response to a single dose, or to repeated doses of ACTH.


Author(s):  
T. M. Murad ◽  
Karen Israel ◽  
Jack C. Geer

Adrenal steroids are normally synthesized from acetyl coenzyme A via cholesterol. Cholesterol is also shown to enter the adrenal gland and to be localized in the lipid droplets of the adrenal cortical cells. Both pregnenolone and progesterone act as intermediates in the conversion of cholesterol into steroid hormones. During pregnancy an increased level of plasma cholesterol is known to be associated with an increase of the adrenal corticoid and progesterone. The present study is designed to demonstrate whether the adrenal cortical cells show any dynamic changes during pregnancy.


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