Determination of vanadium in high grade carbons by radioanalytical methods

1980 ◽  
Vol 59 (1) ◽  
pp. 23-30 ◽  
Author(s):  
K. Jinno ◽  
M. Sato ◽  
S. Amemiya ◽  
T. Katoh
Keyword(s):  
High Grade ◽  
Radioanalytical Methods

scholarly journals Residual Convolutional Neural Network for the Determination of IDH Status in Low- and High-Grade Gliomas from MR Imaging

2017 ◽  
Vol 24 (5) ◽  
pp. 1073-1081 ◽  
Author(s):  
Ken Chang ◽  
Harrison X. Bai ◽  
Hao Zhou ◽  
Chang Su ◽  
Wenya Linda Bi ◽  
...  
Keyword(s):  
Neural Network ◽  
Mr Imaging ◽  
Convolutional Neural Network ◽  
High Grade ◽  
High Grade Gliomas

Primary Ta high grade bladder tumors: Determination of the risk of progression

2020 ◽  
Author(s):  
Fahad Quhal ◽  
David D'Andrea ◽  
Francesco Soria ◽  
Marco Moschini ◽  
Mohammad Abufaraj ◽  
...  
Keyword(s):  
High Grade ◽  
Bladder Tumors ◽  
Risk Of Progression

scholarly journals Grade Information and Grade Inflation: The Cornell Experiment

2009 ◽  
Vol 23 (3) ◽  
pp. 93-108 ◽  
Author(s):  
Talia Bar ◽  
Vrinda Kadiyali ◽  
Asaf Zussman
Keyword(s):  
Student Behavior ◽  
Grade Inflation ◽  
High Grade ◽  
Faculty Senate ◽  
Cornell University ◽  
Letter Grades ◽  
Grade Levels ◽  
The University ◽  
High Ability Students

Grade inflation and high grade levels have been subjects of concern and public debate in recent decades. In the mid-1990s, Cornell University's Faculty Senate had a number of discussions about grade inflation and what might be done about it. In April 1996, the Faculty Senate voted to adopt a new grade reporting policy which had two parts: 1) the publication of course median grades on the Internet; and 2) the reporting of course median grades in students' transcripts. The policy change followed the determination of a university committee that “it is desirable for Cornell University to provide more information to the reader of a transcript and produce more meaningful letter grades.” It was hoped that “More accurate recognition of performance may encourage students to take courses in which the median grade is relatively low.” The median grade policy has remained to date only partially implemented: median grades have been reported online since 1998 but do not yet appear in transcripts. We evaluate the effect of the implemented policy on patterns of course choice and grade inflation. Specifically, we test two related hypotheses: First, all else being equal, the availability of online grade information will lead to increased enrollment into leniently graded courses. Second, high-ability students will be less attracted to the leniently graded courses than their peers. Building on these results we perform an exercise that identifies the extent to which the change in student behavior resulted in an increase in the university-wide mean grade.

Determination of expression of platelet derived growth factor receptors (PDGFR) in astrocitic tumors

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 11518-11518 ◽  
Author(s):  
C. H. Barrios ◽  
F. S. Viola ◽  
L. M. Coutinho ◽  
E. Paglioli
Keyword(s):  
Tumor Vasculature ◽  
Molecular Target ◽  
Platelet Derived Growth Factor ◽  
Low Grade ◽  
High Grade ◽  
Santa Cruz ◽  
Cell Compartment ◽  
Oncology Unit

11518 Background: PDGF and its receptors (α and β) are frequently expressed together in gliomas raising the possibility that an autocrine/paracrine loop could contribute to the pathogenesis of these tumors. Studies with immunohistochemistry (IHC) and in situ hybridization have clarified that PDGF-α receptors (PDGF-R α) are preferentially expressed in tumor cells, whereas PDGF-β receptors (PDGF-R β) are preferentially expressed in proliferating endotelial cells within the tumor vasculature. Objective: Determine the expression of PDGF-R α and β in astrocitic tumors. Methods: Paraffin blocks samples from patients with a diagnosis of low-grade astrocitoma, anaplastic astrocitoma, and glioblastoma were obtained from the Neuro-Oncology Unit at Hospital São Lucas-PUCRS. These patients presented and were treated from 1996 through 2001. We collected a total of 130 cases: 57 Low-grade astrocitomas (LGA), 13 Anaplastic Astrocitomas (AA), and 60 Glioblastomas (GBM). All cases were studied with standard IHC techniques using antibodies for PDGFR α and β (Santa Cruz Biotechnology). Results: See table . Conclusion: The expression of PDGF-R α and β in low-grade tumors reflects the possible role these receptors may have in the evolution of these neoplasms. More importantly we documented that over 60% of high-grade gliomas (61% in AA; 65% in GBM) show expression of PDGF-R β predominantly in the endothelial cell compartment of the tumors. This is consistent with and reflects the extensive angiogenesis observed in these diseases. The level of expression we encountered identifies an attractive molecular target to explore. [Table: see text] No significant financial relationships to disclose.

PFS by blinded independent central review (BICR) in the VELIA trial of veliparib (V) plus carboplatin/paclitaxel (CP) and as monotherapy in newly diagnosed patients (pts) with high-grade serous ovarian cancer (HGSC).

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. 6077-6077
Author(s):  
Carol Aghajanian ◽  
Michael A. Bookman ◽  
Gini F. Fleming ◽  
Mark F. Brady ◽  
Elizabeth M. Swisher ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Safety Data ◽  
Phase Iii ◽  
High Grade ◽  
Serous Ovarian Cancer ◽  
Newly Diagnosed ◽  
Primary Analysis ◽  
Population Analyses ◽  
Clinical Trial Information

6077 Background: The phase III VELIA trial (NCT02470585) demonstrated statistically significant improvement in PFS per investigator (INV) for V added to CP and continued as maintenance (CPV-V) vs. CP alone in pts with newly diagnosed HGSC in the BRCA mutated ( BRCAm), homologous recombination deficient (HRD), and whole populations. Here we present pre-specified analyses of PFS per BICR. Methods: Pts with Stage III-IV HGSC received V or Placebo (PL) with CP (6 cycles) and as maintenance (30 additional cycles). Primary analysis of PFS by INV compared CPV-V to CP alone in the BRCAm, HRD, and whole populations. Exploratory analyses of PFS in BRCA wildtype (wt) and non-HRD HGSC were performed. Radiologic tumor assessments were also prospectively submitted to an independent central reviewer for blinded assessment per RECIST v 1.1. PFS per BICR and rates of concordance between INV and BICR for determination of disease progression were analyzed. Safety data from the primary analysis were previously reported. Results: 1140 total pts were enrolled (CPV-V 382; CP 375). In the whole population, 26% of HGSCs were BRCAm and 55% were HRD. Concordance rates between INV and BICR were 68-85% by arm for each population. Analyses of PFS per BICR and per INV were consistent (Table). PFS was prolonged in the CPV-V vs. CP arm in all primary and exploratory populations assessed. Conclusions: Analyses of PFS per BICR supported the primary analysis of PFS per INV in the BRCAm, HRD, and whole populations, as well as exploratory BRCAwt and non-HRD populations. Median PFS per BICR was longer compared to PFS per INV assessments in all populations and in both arms. These findings support the reliability of PFS by INV in ovarian cancer trials. Alternate strategies like audits may be appropriate to support PFS by INV with less time and expense than full BICR. Clinical trial information: NCT02470585. [Table: see text]

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