HPLC determination of pefloxacin and ciprofloxacin in blood serum

1999 ◽  
Vol 33 (4) ◽  
pp. 219-221 ◽  
Author(s):  
G. É. Brkich ◽  
A. P. Arzamastsev ◽  
É. M. Kaz'mina ◽  
A. V. Mikhalev
1996 ◽  
Vol 30 (2) ◽  
pp. 130-131 ◽  
Author(s):  
O. I. Kal'chenko ◽  
L. M. Zaitsev ◽  
B. M. Klebanov ◽  
I. I. Krasavtsev ◽  
Yu. V. Korotkii ◽  
...  

2006 ◽  
Vol 42 (1) ◽  
pp. 113-119 ◽  
Author(s):  
Zofia Suchocka ◽  
Joanna Swatowska ◽  
Jan Pachecka ◽  
Piotr Suchocki

2008 ◽  
Vol 41 (5) ◽  
pp. 757-766 ◽  
Author(s):  
R. Ghali ◽  
K. Hmaissia‐Khlifa ◽  
Ch. Mezigh ◽  
H. Ghorbel ◽  
K. Maaroufi ◽  
...  

2006 ◽  
Vol 40 (12) ◽  
pp. 683-685
Author(s):  
S. N. Ptitsina ◽  
V. I. Bobrov ◽  
L. N. Serov ◽  
M. M. Borisov ◽  
I. Kh. Ivanova ◽  
...  

1980 ◽  
Vol 45 (4) ◽  
pp. 1099-1108 ◽  
Author(s):  
Mikuláš Chavko ◽  
Michal Bartík ◽  
Evžen Kasafírek

A polarographic study of the hydrolysis of [8-lysine]vasopressin and some hormonogens of the vasopressin series with the blood serum of women in the last week of pregnancy was studied. The dependence of hydrolysis on pH (pH optimum: 7.4-7.50, substrate concentration (Km 1.2 . 10-5M), pH stability and thermal stability were determined. The rate of hydrolysis of individual vasopressin analogues decreases in the order: [8-lysine]vasopressin > Nα-glycyl-prolyl[8-lysine]-vasopressin > Nα-leucyl-[8-lysine]vasopressin > Nα-alanyl-[8-lysine]vasopressin > Nα-phenyl alanyl-[8-lysine]vasopressin > Nα-diglycyl-[8-lysine]vasopressin > Nα-prolyl-[8-lysine]vasopressin > Nα-triglycyl-[8-lysine]vasopressin > Nα-sarcosyl-glycyl-[8-lysine]vasopressin. The degree of hydrolysis gradually increases to a multiple with the length of the pregnancy in consequence of the presence of oxytocine. However, vasopressin is also hydrolysed to a small extent with the enzymes from the blood sera of non-pregnant women. Under similar analytical conditions oxytocin was not hydrolysed with the sera of non-pregnant women and therefore oxytocin is a more suitable substrate than vasopressin for polarographic determination of serum oxytocinase.


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