Effects of low-dose long-term sodium fluoride preventive treatment on rat bone mass and biomechanical properties

1996 ◽  
Vol 58 (1) ◽  
pp. 30-39 ◽  
Author(s):  
Y. Jiang ◽  
J. Zhao ◽  
R. Van Audekercke ◽  
J. Dequeker ◽  
P. Geusens
Keyword(s):  
Bone Mass ◽  
Sodium Fluoride ◽  
Low Dose ◽  
Preventive Treatment ◽  
Biomechanical Properties ◽  
Rat Bone

Effects of Low-Dose Long-Term Sodium Fluoride Preventive Treatment on Rat Bone Mass and Biomechanical Properties

1996 ◽  
Vol 58 (1) ◽  
pp. 30-39 ◽  
Author(s):  
Y. Jiang ◽  
J. Zhao ◽  
R. Van Audekercke ◽  
J. Dequeker ◽  
P. Geusens
Keyword(s):  
Bone Mass ◽  
Sodium Fluoride ◽  
Low Dose ◽  
Preventive Treatment ◽  
Biomechanical Properties ◽  
Rat Bone

The Effect of Long-Term Low-Dose Diphosphonate Treatment on Rat Bone

1982 ◽  
Vol &NA; (165) ◽  
pp. 290???299
Author(s):  
RICHARD A. EVANS ◽  
C. ROLFE HOWLETT ◽  
COLIN R. DUNSTAN ◽  
ELLEN HILLS
Keyword(s):  
Low Dose ◽  
Rat Bone

Ovarian Dysfunction in Fetally Irradiated Beagles

1977 ◽  
Vol 35 ◽  
pp. 658-659
Author(s):  
T. M. Seed ◽  
M. H. Sanderson ◽  
D. L. Gutzeit ◽  
T. E. Fritz ◽  
D. V. Tolle ◽  
...  
Keyword(s):  
Gamma Rays ◽  
Low Dose ◽  
Long Term Effects ◽  
Ovarian Dysfunction ◽  
Dose Rates ◽  
Highly Sensitive ◽  
Microscopic Evaluation ◽  
Ovarian Pathology ◽  
Normal Offspring

The developing mammalian fetus is thought to be highly sensitive to ionizing radiation. However, dose, dose-rate relationships are not well established, especially the long term effects of protracted, low-dose exposure. A previous report (1) has indicated that bred beagle bitches exposed to daily doses of 5 to 35 R 60Co gamma rays throughout gestation can produce viable, seemingly normal offspring. Puppies irradiated in utero are distinguishable from controls only by their smaller size, dental abnormalities, and, in adulthood, by their inability to bear young.We report here our preliminary microscopic evaluation of ovarian pathology in young pups continuously irradiated throughout gestation at daily (22 h/day) dose rates of either 0.4, 1.0, 2.5, or 5.0 R/day of gamma rays from an attenuated 60Co source. Pups from non-irradiated bitches served as controls. Experimental animals were evaluated clinically and hematologically (control + 5.0 R/day pups) at regular intervals.

The Acute Effect of Alcohol on Various Memory Processes

2010 ◽  
Vol 24 (4) ◽  
pp. 249-252 ◽  
Author(s):  
Márk Molnár ◽  
Roland Boha ◽  
Balázs Czigler ◽  
Zsófia Anna Gaál
Keyword(s):  
Low Dose ◽  
Short Term Memory ◽  
Acute Effect ◽  
Long Term Memory ◽  
Term Memory ◽  
Memory Processes ◽  
Different Types ◽  
The Brain ◽  
Legal Consequences

This review surveys relevant and recent data of the pertinent literature regarding the acute effect of alcohol on various kinds of memory processes with special emphasis on working memory. The characteristics of different types of long-term memory (LTM) and short-term memory (STM) processes are summarized with an attempt to relate these to various structures in the brain. LTM is typically impaired by chronic alcohol intake but according to some data a single dose of ethanol may have long lasting effects if administered at a critically important age. The most commonly seen deleterious acute effect of alcohol to STM appears following large doses of ethanol in conditions of “binge drinking” causing the “blackout” phenomenon. However, with the application of various techniques and well-structured behavioral paradigms it is possible to detect, albeit occasionally, subtle changes of cognitive processes even as a result of a low dose of alcohol. These data may be important for the consideration of legal consequences of low-dose ethanol intake in conditions such as driving, etc.

Long-term high-dose resveratrol supplementation reduces bone mass and strength in rats

2016 ◽  
Author(s):  
Ornstrup Marie Juul ◽  
Annemarie Bruel ◽  
Thomsen Jesper Skovhus ◽  
Torben Harslof ◽  
Langdahl Bente Lomholt ◽  
...  
Keyword(s):  
Bone Mass ◽  
High Dose

Effects of long-term sedentary behaviour on the cortical bone mass and distribution during growth: The HAPPY bone study

2017 ◽  
Author(s):  
Rachel L Duckham ◽  
Timo Rantalainen ◽  
Christine Rodda ◽  
Anna Timperio ◽  
Nicola Hawley ◽  
...  
Keyword(s):  
Bone Mass ◽  
Cortical Bone ◽  
Sedentary Behaviour ◽  
Cortical Bone Mass
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