Is the lectin binding pattern of human breast and colon cancer cells influenced by modulators of sialic acid metabolism?

1996 ◽  
Vol 106 (6) ◽  
pp. 599-604 ◽  
Author(s):  
Udo Schumacher ◽  
Dhia Mukhtar ◽  
Peer Stehling ◽  
Werner Reutter
Keyword(s):  
Colon Cancer ◽  
Sialic Acid ◽  
Cancer Cells ◽  
Acid Metabolism ◽  
Lectin Binding ◽  
Binding Pattern ◽  
Colon Cancer Cells ◽  
Human Breast

Purified mulberry leaf lectin (MLL) induces apoptosis and cell cycle arrest in human breast cancer and colon cancer cells

2012 ◽  
Vol 200 (1) ◽  
pp. 38-44 ◽  
Author(s):  
Mundekkad Deepa ◽  
Thavamani Sureshkumar ◽  
Padikara Kutty Satheeshkumar ◽  
Sulochana Priya
Keyword(s):  
Breast Cancer ◽  
Cell Cycle ◽  
Colon Cancer ◽  
Cell Cycle Arrest ◽  
Cancer Cells ◽  
Human Breast Cancer ◽  
Colon Cancer Cells ◽  
Human Breast ◽  
Mulberry Leaf ◽  
Cycle Arrest

scholarly journals The Impact of Extracellular Ca2+ and Nanosecond Electric Pulses on Sensitive and Drug-Resistant Human Breast and Colon Cancer Cells

Cancers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 3216
Author(s):  
Julita Kulbacka ◽  
Nina Rembiałkowska ◽  
Anna Szewczyk ◽  
Helena Moreira ◽  
Anna Szyjka ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Colon Cancer ◽  
Drug Resistance ◽  
Cancer Cells ◽  
Calcium Ions ◽  
Colon Cancer Cells ◽  
Human Breast ◽  
The Impact ◽  
Mcf 7 ◽  
Resistant Cells

(1) Background: Calcium electroporation (CaEP) is based on the application of electrical pulses to permeabilize cells (electroporation) and allow cytotoxic doses of calcium to enter the cell. (2) Methods: In this work, we have used doxorubicin-resistant (DX) and non-resistant models of human breast cancer (MCF-7/DX, MCF-7/WT) and colon cancer cells (LoVo, LoVo/DX), and investigated the susceptibility of the cells to extracellular Ca2+ and electric fields in the 20 ns–900 ns pulse duration range. (3) Results: We have observed that colon cancer cells were less susceptible to PEF than breast cancer cells. An extracellular Ca2+ (2 mM) with PEF was more disruptive for DX-resistant cells. The expression of glycoprotein P (MDR1, P-gp) as a drug resistance marker was detected by the immunofluorescent (CLSM) method and rhodamine-123 efflux as an MDR1 activity. MDR1 expression was not significantly modified by nanosecond electroporation in multidrug-resistant cells, but a combination with calcium ions significantly inhibited MDR1 activity and cell viability. (4) Conclusions: We believe that PEF with calcium ions can reduce drug resistance by inhibiting drug efflux activity. This phenomenon of MDR mechanism disruption seems promising in anticancer protocols.

Anti‐tumor activity of the ethanolic extract of Micromeria fruticosa on human breast and colon cancer cells

2020 ◽  
Vol 34 (S1) ◽  
pp. 1-1 ◽  
Author(s):  
Eman Abu-Gharbieh ◽  
Waseem El-Huneidi ◽  
Naglaa G. Shehab ◽  
Khuloud Bajbouj ◽  
Arya Vinod ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Cells ◽  
Ethanolic Extract ◽  
Colon Cancer Cells ◽  
Human Breast ◽  
Anti Tumor Activity ◽  
Micromeria Fruticosa

Luteolin impairs hypoxia adaptation and progression in human breast and colon cancer cells

2020 ◽  
Vol 881 ◽  
pp. 173210 ◽  
Author(s):  
Elena Monti ◽  
Emanuela Marras ◽  
Pamela Prini ◽  
Marzia Bruna Gariboldi
Keyword(s):  
Colon Cancer ◽  
Cancer Cells ◽  
Colon Cancer Cells ◽  
Human Breast ◽  
Hypoxia Adaptation
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