Thymidine labeling index in breast tumors

1990 ◽  
Vol 20 (2) ◽  
pp. 180-185 ◽  
Author(s):  
Hy De Lee Euy ◽  
Young Soh ◽  
Hoon Sang Chi ◽  
Byong Ro Kim ◽  
Kyong Sik Lee ◽  
...  
Keyword(s):  
Breast Tumors ◽  
Labeling Index ◽  
Thymidine Labeling Index

Increased tritiated thymidine-labeling index of bone marrow myeloblasts following BCG administration in man

1978 ◽  
Vol 4 (3) ◽  
pp. 197-199
Author(s):  
M. Rozencweig ◽  
P. Stryckmans ◽  
J.P. Fichefet ◽  
Mireille Socquet
Keyword(s):  
Bone Marrow ◽  
Tritiated Thymidine ◽  
Labeling Index ◽  
Thymidine Labeling Index

Thymidine Labeling Index Analysis in Early Breast Cancer Patients Randomized to Receive Perioperative Chemotherapy

Oncology ◽  
2000 ◽  
Vol 60 (1) ◽  
pp. 88-93 ◽  
Author(s):  
Paolo Pronzato ◽  
Paola Queirolo ◽  
Stefania Vecchio ◽  
Rita Lionetto ◽  
Lucia Del Mastro ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Early Breast Cancer ◽  
Labeling Index ◽  
Perioperative Chemotherapy ◽  
Breast Cancer Patients ◽  
Index Analysis ◽  
Thymidine Labeling Index ◽  
To Receive

scholarly journals A simple rapid autoradiography for3H-thymidine labeling index and its application to therapy of adult acute leukemia

Cancer ◽  
1980 ◽  
Vol 46 (10) ◽  
pp. 2298-2307 ◽  
Author(s):  
Takashi Yoshida ◽  
Ken-Ichi Hattori ◽  
Shinobu Nakamura ◽  
Eiichi Mitamura ◽  
Saburo Kobayashi ◽  
...  
Keyword(s):  
Acute Leukemia ◽  
Labeling Index ◽  
Thymidine Labeling Index

Studies on3H-thymidine Labeling Index of Bone Marrow Cells in Various Childhood Disorders

1970 ◽  
Vol 12 (1) ◽  
pp. 39-41
Author(s):  
Yutaka Ueda ◽  
Keiji Ibuka ◽  
Masao Yamamoto ◽  
Masahiko Kuwabara ◽  
Yutaka Takahata
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Cells ◽  
Labeling Index ◽  
Childhood Disorders ◽  
Thymidine Labeling Index ◽  
Marrow Cells

scholarly journals Reinitiation of DNA synthesis in senescent human fibroblasts upon fusion with cells of unlimited growth potential.

1975 ◽  
Vol 64 (3) ◽  
pp. 551-556 ◽  
Author(s):  
T H Norwood ◽  
W R Pendergrass ◽  
G M Martin
Keyword(s):  
Dna Synthesis ◽  
Sendai Virus ◽  
Human Fibroblasts ◽  
Growth Potential ◽  
Labeling Index ◽  
Thymidine Labeling Index ◽  
Unlimited Growth

Postreplicative, "senescent" human fibroblasts were fused to HeLa or to SV-40 transformed human fibroblasts with Sendai virus. DNA synthesis was reinitiated in senescent nuclei in a high proportion of the heterodikaryons. The [3H]thymidine labeling index of senescent fibroblast nuclei in heteropolykaryons was a function of the ratio of HeLa to senescent nuclei.

Skin calcium binding protein: effect of ultraviolet B irradiation

1986 ◽  
Vol 251 (3) ◽  
pp. C329-C334 ◽  
Author(s):  
M. Rizk ◽  
L. Didierjean ◽  
J. H. Pavlovitch
Keyword(s):  
Calcium Binding ◽  
Binding Protein ◽  
Basal Layer ◽  
Calcium Binding Protein ◽  
Ultraviolet B ◽  
Labeling Index ◽  
Humoral Factors ◽  
Low Degree ◽  
Thymidine Labeling Index ◽  
Uvb Exposure

Skin calcium binding protein (SCaBP) has been found in the epidermal basal layer but not in the suprabasal layers, suggesting that its presence is correlated with the position of the cell and/or the cells' low degree of differentiation and high proliferation capacity. Rats were exposed to ultraviolet B (UVB) irradiation (280-320 nm, 0.1 J/cm2) to dissociate these two main characteristics of basal layer cells. Skin biopsy specimens were taken 24 and 48 h after UVB exposure. The [3H]thymidine labeling index, SCaBP localization (indirect immunofluorescence), and SCaBP levels monitored by radioimmunoassay were investigated. The [3H]thymidine labeling index was significantly increased after UVB treatment, and the [3H]thymidine-labeled cells were present not only in the basal layer but also in the suprabasal epidermal layers. Anti-SCaBP immunofluorescence was observed in both suprabasal and basal layers (rather than exclusively in the basal layer, as in control conditions). The radioimmunoassay indicated an overall increase in skin SCaBP content. No evidence was obtained that this increase was due to humoral factors, as no changes in SCaBP concentration on cell proliferation were observed in nonirradiated epidermal areas. Topical application of a single dose of vitamin D3, equivalent to the amount synthesized by UVB exposure, was also without effect. Thus the presence of this marker is correlated with the low degree of cell maturity and the cells' ability to proliferate rather than their basal position.

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