Sequential assays of hormone receptors and the tritiated thymidine labeling index in 7,12-dimethylbenz(a)anthracene-induced rat mammary cancers

1985 ◽  
Vol 15 (2) ◽  
pp. 150-159 ◽  
Author(s):  
Keisuke Araki ◽  
Masaharu Kimura ◽  
Kiyoshi Sakamoto ◽  
Reiki Nishimura ◽  
Junichi Yamashita ◽  
...  
Keyword(s):  
Hormone Receptors ◽  
Tritiated Thymidine ◽  
Labeling Index ◽  
Thymidine Labeling Index

Increased tritiated thymidine-labeling index of bone marrow myeloblasts following BCG administration in man

1978 ◽  
Vol 4 (3) ◽  
pp. 197-199
Author(s):  
M. Rozencweig ◽  
P. Stryckmans ◽  
J.P. Fichefet ◽  
Mireille Socquet
Keyword(s):  
Bone Marrow ◽  
Tritiated Thymidine ◽  
Labeling Index ◽  
Thymidine Labeling Index

3H-Thymidine labeling index, hormone receptors, and ploidy in breast cancers from elderly patients

1991 ◽  
Vol 20 (1) ◽  
pp. 19-24 ◽  
Author(s):  
B. Valentinis ◽  
R. Silvestrini ◽  
M. G. Daidone ◽  
D. Coradini ◽  
E. Galante ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Hormone Receptors ◽  
Labeling Index ◽  
Breast Cancers ◽  
Thymidine Labeling Index

scholarly journals Megakaryocytopoiesis in Experimental Iron Deficiency Anemia

Blood ◽  
1974 ◽  
Vol 43 (1) ◽  
pp. 111-120 ◽  
Author(s):  
Sun I Choi ◽  
Joseph V. Simone ◽  
C. W. Jackson
Keyword(s):  
Iron Deficiency ◽  
Mitotic Index ◽  
Iron Deficiency Anemia ◽  
Tritiated Thymidine ◽  
Labeling Index ◽  
Deficiency Anemia ◽  
Platelet Production ◽  
Thymidine Labeling Index ◽  
Moderate Anemia ◽  
Immature Cells

Abstract Iron deficiency anemia is associated with increased platelet production. The megakaryocytic response to both moderate and severe iron deficiency anemia has been assessed in rats maintained on a low-iron diet. In animals with moderate anemia, the proportion of immature megakaryocytes and 24-hr tritiated thymidine labeling index were increased with no change in megakaryocyte concentration, size, or mitotic index. This indicates that increased platelet production is achieved by an increased rate of influx of precursor cells into the megakaryocyte compartment with an increased rate of efflux. In severe anemia, however, not only were the labeling index and the proportion of immature cells increased, but megakaryocyte size and mitotic index were significantly increased with a marked decrease in megakaryocyte concentration. This suggests that the circulating platelet mass is maintained by an increased platelet output per megakaryocyte with higher ploidy. Thus, in chronic iron deficiency anemia, megakaryocytopoiesis changes depending on the duration and degree of iron deficiency, with a more rapid turnover at first and increased polyploidy later.

Significance of the tritiated thymidine labeling index in breast cancers

1985 ◽  
Vol 15 (2) ◽  
pp. 144-149 ◽  
Author(s):  
Keisuke Araki ◽  
Masaharu Kimura ◽  
Kiyoshi Sakamoto ◽  
Reiki Nishimura ◽  
Masanobu Akagi
Keyword(s):  
Tritiated Thymidine ◽  
Labeling Index ◽  
Breast Cancers ◽  
Thymidine Labeling Index
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