Gastric carcinoma with lymphoid stroma: Correlation to reactive hyperplasia in regional lymph nodes and prognosis

1983 ◽  
Vol 13 (3) ◽  
pp. 177-183 ◽  
Author(s):  
Takeshi Okamura ◽  
Yoshifumi Kodama ◽  
Takahisa Kamegawa ◽  
Chiaki Sano ◽  
Ryunosuke Kumashiro ◽  
...  
2014 ◽  
Vol 59 (1) ◽  
pp. 47-51 ◽  
Author(s):  
Mariusz Gryko ◽  
Katarzyna Guzińska-Ustymowicz ◽  
Joanna Kiśluk ◽  
Dariusz Cepowicz ◽  
Andrzej Kemona ◽  
...  

Cancer ◽  
2000 ◽  
Vol 88 (11) ◽  
pp. 2438-2442 ◽  
Author(s):  
Kenjiro Nakamura ◽  
Takashi Morisaki ◽  
Hirokazu Noshiro ◽  
Nobuhiro Torata ◽  
Naoko Kinukawa ◽  
...  

1994 ◽  
Vol 85 (6) ◽  
pp. 652-658 ◽  
Author(s):  
Yoshimi Akamo ◽  
Isamu Mizuno ◽  
Toshihisa Yotsuyanagi ◽  
Tatsuo Ichino ◽  
Noritaka Tanimoto ◽  
...  

Author(s):  
Tatjana Tone ◽  
Elīna Tauvēna ◽  
Ilze Štrumfa ◽  
Jānis Gardovskis

AbstractThe study represents a comprehensive retrospective morphological profiling of gastric carcinoma in order to reveal associations between certain tumour-infiltrating inflammatory cells and clinical and/or pathological parameters. Patients’ age and gender, the extent of local tumour spread (pT), presence of metastases in regional lymph nodes (pN), tumour grade (G) as well as type according to World Health Organisation (WHO) and Lauren classifications were assessed in 211 consecutive surgically resected gastric carcinomas. Tumour-infiltrating inflammatory cells including eosinophils, neutrophils and lymphocytes were counted within the cancer stroma in five randomly selected high-power fields representative of the tumour. Descriptive statistics, Mann–Whitney and Kruskal–Wallis tests were applied; p < 0.05 was considered significant. Higher number of stromal eosinophils was associated with absence of metastases in regional lymph nodes (pN0) and histological structure of adenocarcinoma by WHO classification (p = 0.005 and p = 0.002, respectively). Higher count of stromal neutrophils showed significant associations with younger age (less than 65 years), and intestinal type by Lauren classification (p = 0.029 and p = 0.007, respectively). The density of stromal lymphocytes lacked any statistically significant association with the evaluated clinical or morphological parameters. In conclusion, the current study highlights the links between certain innate immune system cells and morphological features of gastric carcinoma.


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