The method of frontal polyhedra for conformationally-nonrigid molecules. Quantitative structure—Activity relationship in the series of baker triazines—Dihydrofolate reductase inhibitors

A. I. Khlebnikov

doi:10.1007/bf02464669

The method of frontal polyhedra for conformationally-nonrigid molecules. Quantitative structure—Activity relationship in the series of baker triazines—Dihydrofolate reductase inhibitors

Pharmaceutical Chemistry Journal ◽

10.1007/bf02464669 ◽

1997 ◽

Vol 31 (3) ◽

pp. 147-154 ◽

Cited By ~ 1

Author(s):

A. I. Khlebnikov

Keyword(s):

Dihydrofolate Reductase ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Nonrigid Molecules ◽

Reductase Inhibitors ◽

Structure Activity ◽

Dihydrofolate Reductase Inhibitors

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ChemInform Abstract: QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP BY DISTANCE GEOMETRY: QUINAZOLINES AS DIHYDROFOLATE REDUCTASE INHIBITORS

Chemischer Informationsdienst ◽

10.1002/chin.198304225 ◽

1983 ◽

Vol 14 (4) ◽

Author(s):

A. K. GHOSE ◽

G. M. CRIPPEN

Keyword(s):

Dihydrofolate Reductase ◽

Distance Geometry ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Reductase Inhibitors ◽

Structure Activity ◽

Dihydrofolate Reductase Inhibitors

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Quantitative structure-activity relationship by distance geometry: quinazolines as dihydrofolate reductase inhibitors

Journal of Medicinal Chemistry ◽

10.1021/jm00350a003 ◽

1982 ◽

Vol 25 (8) ◽

pp. 892-899 ◽

Cited By ~ 29

Author(s):

Arup K. Ghose ◽

Gordon M. Crippen

Keyword(s):

Dihydrofolate Reductase ◽

Distance Geometry ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Reductase Inhibitors ◽

Structure Activity ◽

Dihydrofolate Reductase Inhibitors

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ChemInform Abstract: QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP OF REVERSIBLE DIHYDROFOLATE REDUCTASE INHIBITORS, DIAMINOTRIAZINES

Chemischer Informationsdienst ◽

10.1002/chin.197446330 ◽

1974 ◽

Vol 5 (46) ◽

pp. no-no

Author(s):

C. HANSCH ◽

C. SILIPO

Keyword(s):

Dihydrofolate Reductase ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Reductase Inhibitors ◽

Structure Activity ◽

Relationship Of ◽

Dihydrofolate Reductase Inhibitors

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Dihydrofolate reductase inhibitors: a quantitative structure–activity relationship study using 2D-QSAR and 3D-QSAR methods

Medicinal Chemistry Research ◽

10.1007/s00044-016-1742-4 ◽

2016 ◽

Vol 26 (1) ◽

pp. 247-261 ◽

Cited By ~ 5

Author(s):

Juan C. Garro Martinez ◽

Matias F. Andrada ◽

Esteban G. Vega-Hissi ◽

Francisco M. Garibotto ◽

Manuel Nogueras ◽

...

Keyword(s):

Dihydrofolate Reductase ◽

3D Qsar ◽

Quantitative Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

2D Qsar ◽

Reductase Inhibitors ◽

Structure Activity ◽

Relationship Study ◽

Dihydrofolate Reductase Inhibitors

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Quantitative structure-activity relationship of triazine-antifolate inhibition of Leishmania dihydrofolate reductase and cell growth

Journal of Medicinal Chemistry ◽

10.1021/jm00390a017 ◽

1987 ◽

Vol 30 (7) ◽

pp. 1218-1224 ◽

Cited By ~ 24

Author(s):

Raymond G. Booth ◽

Cynthia Dias Selassie ◽

Corwin Hansch ◽

Daniel V. Santi

Keyword(s):

Cell Growth ◽

Dihydrofolate Reductase ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Structure Activity ◽

Relationship Of

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ChemInform Abstract: INHIBITION OF HUMAN DIHYDROFOLATE REDUCTASE BY 4,6-DIAMINO-1,2-DIHYDRO-2,2-DIMETHYL-1-(SUBSTITUTED-PHENYL)-S-TRIAZINES. A QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP ANALYSIS

Chemischer Informationsdienst ◽

10.1002/chin.198429225 ◽

1984 ◽

Vol 15 (29) ◽

Author(s):

B. A. HATHAWAY ◽

Z. GUO ◽

C. HANSCH ◽

T. J. DELCAMP ◽

S. S. SUSTEN ◽

...

Keyword(s):

Dihydrofolate Reductase ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Relationship Analysis ◽

Structure Activity ◽

Human Dihydrofolate Reductase

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Quantitative Structure Activity Relationship Study of 2,4,6-Trisubstituted-s-triazine Derivatives as Antimalarial Inhibitors of Plasmodium Falciparum Dihydrofolate Reductase

Chemical Biology & Drug Design ◽

10.1111/j.1747-0285.2010.01045.x ◽

2010 ◽

Vol 77 (1) ◽

pp. 57-62 ◽

Cited By ~ 16

Author(s):

Himanshu Ojha ◽

Pragya Gahlot ◽

Anjani K. Tiwari ◽

Mallika Pathak ◽

Rita Kakkar

Keyword(s):

Plasmodium Falciparum ◽

Dihydrofolate Reductase ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Structure Activity ◽

Triazine Derivatives ◽

Relationship Study

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Artificial neural networks applied to the quantitative structure—activity relationship study of dihydropteridine reductase inhibitors

Chemometrics and Intelligent Laboratory Systems ◽

10.1016/0169-7439(93)80086-w ◽

1993 ◽

Vol 19 (1) ◽

pp. 101-109 ◽

Cited By ~ 20

Author(s):

Xin-Hua Song ◽

Ru-Qin Yu

Keyword(s):

Neural Networks ◽

Artificial Neural Networks ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Dihydropteridine Reductase ◽

Quantitative Structure ◽

Reductase Inhibitors ◽

Structure Activity ◽

Relationship Study

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Quantitative structure–activity relationship of spirosuccinimide type aldose reductase inhibitors diminishing sorbitol accumulation in vivo

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2005.12.019 ◽

2006 ◽

Vol 14 (9) ◽

pp. 3090-3097 ◽

Cited By ~ 6

Author(s):

Kwangseok Ko ◽

Hoshik Won ◽

Youngdo Won

Keyword(s):

Aldose Reductase ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity ◽

Relationship Of

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Nonlinear Quantitative Structure−Activity Relationship for the Inhibition of Dihydrofolate Reductase by Pyrimidines

Journal of Medicinal Chemistry ◽

10.1021/jm960197z ◽

1996 ◽

Vol 39 (18) ◽

pp. 3526-3532 ◽

Cited By ~ 16

Author(s):

Jonathan D. Hirst

Keyword(s):

Dihydrofolate Reductase ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Structure Activity

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