Free-radical damage to the liver during its transplantation under conditions of oxidative stress

1995 ◽  
Vol 120 (5) ◽  
pp. 1093-1095
Author(s):  
V. I. Mil'chakov ◽  
I. I. Dement'eva ◽  
M. Yu. Andrianova ◽  
M. V. Palyulina
Keyword(s):  
Oxidative Stress ◽  
Free Radical ◽  
Free Radical Damage ◽  
Radical Damage

scholarly journals The therapeutic implications of oxidative stress in patients receiving haemodialysis

1999 ◽  
Vol 3 (2) ◽  
Author(s):  
AV Crowe ◽  
GM Bell
Keyword(s):  
Oxidative Stress ◽  
Free Radical ◽  
Chemical Species ◽  
Free Radical Damage ◽  
Therapeutic Implications ◽  
Oxygen Derived Free Radicals ◽  
Low Levels ◽  
Free Radical Activity ◽  
Antioxidant Mechanisms ◽  
Radical Damage

Oxygen-derived free radicals are highly reactive chemical species containing an unpaired electron. They are capable of reacting with lipids, proteins and nucleic acids and are thought to have a major role in the pathogenesis of a variety of diseases including atherosclerosis, diabetes and cancer. Antioxidants protect and limit free radical damage and it is the balance between free radical activity and antioxidant mechanisms that determine the potential for tissue damage [1,2]. Oxidative stress exists when there are either low levels of these antioxidants or increased production of reactive oxygen species (ROS).

scholarly journals Oxidative Stress-Mediated Aging during the Fetal and Perinatal Periods

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Lucia Marseglia ◽  
Gabriella D’Angelo ◽  
Sara Manti ◽  
Teresa Arrigo ◽  
Ignazio Barberi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Free Radical ◽  
Periventricular Leukomalacia ◽  
Postnatal Period ◽  
Antioxidant Defenses ◽  
Free Radical Damage ◽  
Radical Generation ◽  
Radical Damage ◽  
In Pregnancy

Oxidative stress is worldwide recognized as a fundamental component of the aging, a process that begins before birth. There is a critical balance between free radical generation and antioxidant defenses. Oxidative stress is caused by an imbalance between the production of free radicals and the ability of antioxidant system to detoxify them. Oxidative stress can occur early in pregnancy and continue in the postnatal period; this damage is implicated in the pathophysiology of pregnancy-related disorders, including recurrent pregnancy loss, preeclampsia and preterm premature rupture of membranes. Moreover, diseases of the neonatal period such as bronchopulmonary dysplasia, retinopathy of prematurity, necrotizing enterocolitis, and periventricular leukomalacia are related to free radical damage. The specific contribution of oxidative stress to the pathogenesis and progression of these neonatal diseases is only partially understood. This review summarizes what is known about the role of oxidative stress in pregnancy and in the pathogenesis of common disorders of the newborn, as a component of the early aging process.

Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rate

2008 ◽  
Vol 44 (3) ◽  
pp. 280-287 ◽  
Author(s):  
Hiroshi Tamura ◽  
Akihisa Takasaki ◽  
Ichiro Miwa ◽  
Ken Taniguchi ◽  
Ryo Maekawa ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Free Radical ◽  
Oocyte Quality ◽  
Fertilization Rate ◽  
Free Radical Damage ◽  
Radical Damage

scholarly journals Oxidative Stress and Cognitive Decline: The Neuroprotective Role of Natural Antioxidants

2021 ◽  
Vol 15 ◽  
Author(s):  
Ferdinando Franzoni ◽  
Giorgia Scarfò ◽  
Sara Guidotti ◽  
Jonathan Fusi ◽  
Muzaffar Asomov ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Central Nervous System ◽  
Nervous System ◽  
Free Radical ◽  
Natural Antioxidants ◽  
High Reactivity ◽  
Free Radical Damage ◽  
The Central Nervous System ◽  
Radical Damage

Free- radicals (Oxygen and Nitrogen species) are formed in mitochondria during the oxidative phosphorylation. Their high reactivity, due to not-engaged electrons, leads to an increase of the oxidative stress. This condition affects above all the brain, that usually needs a large oxygen amount and in which there is the major possibility to accumulate “Reacting Species.” Antioxidant molecules are fundamental in limiting free-radical damage, in particular in the central nervous system: the oxidative stress, in fact, seems to worsen the course of neurodegenerative diseases. The aim of this review is to sum up natural antioxidant molecules with the greatest neuroprotective properties against free radical genesis, understanding their relationship with the Central Nervous System.

3,4-Methylenedioxymethamphetamine (MDMA) Abuse may Cause Oxidative Stress and Potential Free Radical Damage

2003 ◽  
Vol 37 (5) ◽  
pp. 491-497 ◽  
Author(s):  
Jun F. Zhou ◽  
Peng Chen ◽  
Ye H. Zhou ◽  
Liang Zhang ◽  
Huai H. Chen
Keyword(s):  
Oxidative Stress ◽  
Free Radical ◽  
Free Radical Damage ◽  
Radical Damage
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