Effect of interleukin-1β on platelet aggregation in August, Wistar, and WAG rats in acute emotional stress

1997 ◽  
Vol 124 (2) ◽  
pp. 747-750
Author(s):  
S. S. Pertsov ◽  
A. S. Sosnovskii ◽  
A. A. Kubatiev ◽  
G. V. Pirogova
1995 ◽  
Vol 120 (3) ◽  
pp. 884-886 ◽  
Author(s):  
S. S. Pertsov ◽  
T. S. Balashova ◽  
A. A. Kubatiev ◽  
A. S. Sosnovskii ◽  
G. V. Pirogova ◽  
...  

2020 ◽  
Vol 79 ◽  
pp. 23-34
Author(s):  
C. Batandier ◽  
T. Poyot ◽  
N. Marissal-Arvy ◽  
K. Couturier ◽  
F. Canini ◽  
...  

1977 ◽  
Author(s):  
G.F. Gensini ◽  
R. Abbate ◽  
D. Prisco ◽  
G.G. Neri Serneri

Increased platelet aggregation has been observed in various hypercoagulable states, but its predictive value for thrombosis is so far uncertain. We studied the effect of emotional stress and of cigarette smoking on circulating platelets by platelet aggregates ratio (PAR) according to Wu and Hoak (1974.) in medical students aged 20-22 years. The emotional stress was undergoing a University examination.PAR was measured immediately before the examination, at the end and 15 and 30 min after the examination.PAR was significantly lowered in all the subjects at the end (P<0.0l) and after 15 min (P<0.0l) but returned toward normal values after 30 min. The decrease of PAR suggests the production of reversible circulating platelet aggregates. The effect of smo=king a cigarette has been investigated in 8 students. PAR has been determined before smoking, at the end and after 2,5 and 10 min. Smoking lasted 4 min. In 5 subjects we observed a decrease of PAR at 2 min (P< 0. 01), whereas at 5 and 10 min PAR value became normal. Lettuce cigarette smoke did not affect PAR value. Our results indicate that: 1) – Platelet aggregates are very easily produced in circulating blood; 2)- A low value of PAR does not necessarily indicate a platelet hy=peraggregability clinically significant.


Author(s):  
Javier Milagro ◽  
Eduardo Gil ◽  
Jorge Mario Garz�n Rey ◽  
Jordi Aguil� ◽  
Raquel Bail�n

2011 ◽  
Vol 41 (9) ◽  
pp. 1857-1866 ◽  
Author(s):  
A. Steptoe ◽  
G. J. Molloy ◽  
N. Messerly-Bürgy ◽  
A. Wikman ◽  
G. Randall ◽  
...  

BackgroundThe determinants of depression following acute coronary syndrome (ACS) are poorly understood. Triggering of ACS by emotional stress and low socio-economic status (SES) are predictors of adverse outcomes. We therefore investigated whether emotional triggering and low SES predict depression and anxiety following ACS.MethodThis prospective observational clinical cohort study involved 298 patients with clinically verified ACS. Emotional stress was assessed for the 2 h before symptom onset and compared with the equivalent period 24 h earlier using case-crossover methods. SES was defined by household income and education. Depression was measured with the Beck Depression Inventory and the Hamilton Rating Scale for Depression and anxiety with the Hospital Anxiety and Depression Scale 3 weeks after ACS and again at 6 and 12 months. Age, gender, ethnicity, marital status, the Global Registry of Acute Coronary Events risk score, duration of hospital stay and history of depression were included as covariates.ResultsEmotional stress during the 2-h hazard period was associated with increased risk of ACS (odds ratio 1.88, 95% confidence interval 1.01–3.61). Both low income and emotional triggering predicted depression and anxiety at 3 weeks and 6/12 months independently of covariates. The two factors interacted, with the greatest depression and anxiety in lower income patients who experienced acute emotional stress. Education was not related to depression.ConclusionsPatients who experience acute emotional stress during their ACS and are lower SES as defined by current affluence and access to resources are particularly vulnerable to subsequent depression and anxiety.


1983 ◽  
Vol 95 (5) ◽  
pp. 588-590
Author(s):  
V. P. Miroshnichenko ◽  
S. I. Kashtanov ◽  
R. M. Libova ◽  
A. M. Zubovskaya

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