The effect of ciprofloxacin and doxycycline plus metronidazole on lower genital tract flora in patients with proven pelvic inflammatory disease

1991 ◽  
Vol 249 (2) ◽  
pp. 95-101 ◽  
Author(s):  
A. Miettinen ◽  
S. Laine ◽  
K. Teisala ◽  
P. K. Heinonen
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Genital Tract ◽  
Lower Genital Tract

scholarly journals Recovery of Cytomegalovirus and Herpes Simplex Virus from Upper and Lower Genital Tract Specimens Obtained from Women with Pelvic Inflammatory Disease

1997 ◽  
Vol 176 (1) ◽  
pp. 286-288 ◽  
Author(s):  
Lorraine M. Clarke ◽  
Ann Duerr ◽  
Kam‐Ha Anna Yeung ◽  
Susan Brockman ◽  
Cibele Barbosa ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Genital Tract ◽  
Lower Genital Tract ◽  
Simplex Virus

scholarly journals A Practical Approach to the Diagnosis of Pelvic Inflammatory Disease

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Oluwatosin Jaiyeoba ◽  
David E. Soper
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Genital Tract ◽  
Cost Effective ◽  
Transmitted Infection ◽  
Clinical Criteria ◽  
Sexually Transmitted ◽  
Lower Genital Tract ◽  
Acute Pelvic Inflammatory Disease ◽  
High Index Of Suspicion

The diagnosis of acute pelvic inflammatory disease (PID) is usually based on clinical criteria and can be challenging for even the most astute clinicians. Although diagnostic accuracy is advocated, antibiotic treatment should be instituted if there is a diagnosis of cervicitis or suspicion of acute PID. Currently, no single test or combination of diagnostic indicators have been found to reliably predict PID, and laparoscopy cannot be recommended as a first line tool for PID diagnosis. For this reason, the clinician is left with maintaining a high index of suspicion for the diagnosis as he/she evaluates the lower genital tract for inflammation and the pelvic organs for tenderness in women with genital tract symptoms and a risk for sexually transmitted infection. This approach should minimize treating women without PID with antibiotics and optimize the diagnosis in a practical and cost-effective way.

Staphylococcus sciuri: an unusual cause of pelvic inflammatory disease

2005 ◽  
Vol 16 (6) ◽  
pp. 452-453 ◽  
Author(s):  
S Stepanović ◽  
P Ježek ◽  
I Dakić ◽  
D Vuković ◽  
L Seifert
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Streptococcus Agalactiae ◽  
Genital Tract ◽  
Female Genital Tract ◽  
Lower Genital Tract ◽  
One Year ◽  
The One ◽  
Low Rate ◽  
Female Genital

We present the case of polymicrobial pelvic inflammatory disease (PID) that involved Staphylococcus sciuri, S. epidermidis, and Streptococcus agalactiae. In order to determine the frequency of S. sciuri isolation from the female lower genital tract, 3415 vaginal samples were analysed during the one-year study period. S. sciuri was isolated from three (0.09%) samples. In all the three cases, S. sciuri was obtained in mixed culture from outpatients without symptoms of infection. While the origin of S. sciuri in the female genital tract remains to be elucidated, the present study showed that this bacterium may colonize vagina and, moreover, may be involved in the pathogenesis of an infection as serious as PID. The low rate of isolation we established, however, indicates infrequent and, most probably, transient colonization of the female genital tract by S. sciuri.

Pelvic inflammatory disease

2020 ◽  
pp. 1622-1625
Author(s):  
Jonathan D.C. Ross
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Pelvic Pain ◽  
Inflammatory Disease ◽  
Genital Tract ◽  
Infectious Complication ◽  
Anaerobic Bacteria ◽  
Clinical Manifestations ◽  
Pelvic Abscess ◽  
Tubal Infertility ◽  
Severe Peritonitis

Pelvic inflammatory disease (PID) is an infection of the endometrium, fallopian tubes, and adnexae caused by a wide variety of bacteria, including Chlamydia trachomatis, Neisseria gonorrhoeae, and genital tract bacteria, most notably anaerobes. PID is often asymptomatic but clinical manifestations can range from mild pelvic pain and tenderness to severe peritonitis. Pelvic abscess formation is a serious infectious complication. However, only about 5% of patients with PID have a fever or severe infectious manifestations. An accurate clinical diagnosis of PID is difficult and it is commonly confused with other pelvic conditions, including ectopic pregnancy, appendicitis, and rupture or torsion of an ovarian cyst. Antibiotic therapy is aimed primarily at C. trachomatis, N. gonorrhoeae, and anaerobic bacteria, with prompt identification and treatment of PID recommended in an attempt to reduce the 15% rate of tubal infertility and 40% risk of chronic pelvic pain following this infection.

The relationship of genital tract actinomycetes and the development of pelvic inflammatory disease

1982 ◽  
Vol 143 (5) ◽  
pp. 585-589 ◽  
Author(s):  
Ronald Burkman ◽  
Sarah Schlesselman ◽  
Lee McCaffrey ◽  
Prabodh K. Gupta ◽  
Michael Spence
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Genital Tract ◽  
Relationship Of ◽  
The Relationship

scholarly journals Unveiling New Molecular Factors Useful for Detection of Pelvic Inflammatory Disease due to Chlamydia trachomatis Infection

2012 ◽  
Vol 2012 ◽  
pp. 1-7
Author(s):  
Carmen Rodriguez-Cerdeira ◽  
Elena Sanchez-Blanco ◽  
Alberto Molares-Vila ◽  
Alfonso Alba
Keyword(s):  
Chlamydia Trachomatis ◽  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Genital Tract ◽  
Nucleic Acid Amplification ◽  
Chlamydia Trachomatis Infection ◽  
Diagnosis And Prognosis ◽  
Pubmed Database ◽  
Genital Tract Infections ◽  
Tract Infections

Background. Untreated Chlamydia trachomatis infections in women can result in disease sequelae such as pelvic inflammatory disease (PID), ultimately culminating in tubal occlusion and infertility. While nucleic acid amplification tests can effectively diagnose uncomplicated lower genital tract infections, they are not suitable for diagnosing upper genital tract pathological sequelae. Objective. The purpose of this paper was to provide a comprehensive review of new molecular factors associated with the diagnosis and prognosis of PID. Material and Methods. The literature was searched using the key words “Chlamydia trachomatis infections,” “pelvic inflammatory disease,” and “molecular factors” in the PubMed database. Relevant articles published between 1996 and 2012 were evaluated. Conclusions. The use of new molecular factors could potentially facilitate earlier diagnosis and prognosis in women with PID due to C. trachomatis infection.

scholarly journals Anti-Inflammatory Effect of Feiyangchangweiyan Capsule on Rat Pelvic Inflammatory Disease through JNK/NF-κB Pathway

2018 ◽  
Vol 2018 ◽  
pp. 1-10
Author(s):  
Yao Li ◽  
Yang Liu ◽  
Qian Yang ◽  
Zhihui Shi ◽  
Yanhua Xie ◽  
...  
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Genital Tract ◽  
Nuclear Translocation ◽  
Immunohistochemical Analysis ◽  
Dependent Manner ◽  
Preventive Effect ◽  
Anti Inflammatory ◽  
Dose Dependent ◽  
Inflammatory Effect

Objectives. In this study, we aimed to illustrate the preventive effect and possible mechanisms of Feiyangchangweiyan capsule (FYCWYC) on rat pelvic inflammatory disease (PID) model. Methods. To construct the rat PID model, upper genital tract was infected by multipathogen, and then drugs were orally administered for 8 days. The histological examination, immunohistochemical analysis, and ELISA were carried out. Furthermore, Western blotting was used to analyze the expression of Akt, MAPKs, NF-κB p65, and IκB-α in uterus. Results. As the results showed, infiltrations of neutrophils and lymphocytes in uterus were significantly suppressed, and IL-1β, IL-6, CXCL-1, and TNF-α were also reduced in a dose-dependent manner. We also found that FYCWYC inhibited apoptosis induced by infection. Furthermore, FYCWYC could block the infection-induced nuclear translocation of NF-κB. We found that FYCWYC treatment only decreased the phosphorylation of JNK induced by infection and had no effects on Akt and P38. Additional, the effects of SP600125, an inhibitor of phospho-JNK, were similar to the results of FYCWYC. Conclusions. Taken together, our results demonstrated that FYCWYC had anti-inflammatory effect in pathogen-induced PID model, and the mechanism might be through inhibiting NF-κB nuclear translocation which is mediated by JNK.

scholarly journals Dynamic laparascopy as a stage of hospital rehabilitation in patients with tubal pregnancy

2005 ◽  
Vol 54 (5S) ◽  
pp. 33-34
Author(s):  
Е. V. Shipitsyna ◽  
А. V. Novikov ◽  
К. V. Shalepo ◽  
V. F. Bezhenar ◽  
А. М. Savicheva
Keyword(s):  
Chlamydia Trachomatis ◽  
Ectopic Pregnancy ◽  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Genital Tract ◽  
Tubal Pregnancy ◽  
Tubal Infertility ◽  
Chlamydia Trachomatis Infection ◽  
Hospital Rehabilitation

Objectives: Chlamydia trachomatis infection of the upper genital tract often results in pelvic inflammatory disease (PID), and its sequels include ectopic pregnancy (EP), miscarriage and tubal infertility. This study was aimed to evaluate the rate of C. trachomatis detection as well as anti-C trachomatis antibodies in women with EP.

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