An attempt to separate a sheep pineal extract fraction showing antigonadotropic activity

1970 ◽  
Vol 32 (1) ◽  
pp. 1-10 ◽  
Author(s):  
I. Ebels ◽  
A. Moszkowska ◽  
A. Scémama
Keyword(s):  
Pineal Extract ◽  
Extract Fraction

scholarly journals Comparative phytotoxicity and chironomid toxicity assessments of leaf successive extract fractions of Asiatic poison bulb, Crinum asiaticum L

2020 ◽  
Author(s):  
Souren Goswami ◽  
Sanjib Ray
Keyword(s):  
Ethyl Acetate ◽  
Petroleum Ether ◽  
Ethyl Acetate Extract ◽  
Antioxidant Properties ◽  
Ethyl Acetate Fraction ◽  
Meristematic Tissue ◽  
Aqueous Fraction ◽  
Extract Fraction ◽  
Potent Growth ◽  
Crinum Asiaticum

AbstractCrinum asiaticum is an evergreen bulbous perennial shrub of Amaryllidaceae family with ethnomedicinal importance and our earlier study described a comparative account antimicrobial and antioxidant properties of the different solvent-mediated sequential extract fractions. The present study aimed to analyze their comparative account of induced phytotoxicity and chironomid toxicity. For phytotoxicity assessment, germination inhibition and seedling’s root and shoot growth retardation effects on Triticum aestivum and Cicer arietinum were analyzed and for lethal concentration determination, the freshwater bottom-dwelling first instars chironomid larvae were used. The crude aqueous, petroleum ether and ethyl acetate extracts showed significant toxic effects on both meristematic tissue and aquatic midges. The phytotoxic assays indicate that the ethyl acetate fraction contains the most potent growth inhibitors, followed by the crude aqueous and petroleum ether fractions. The last aqueous fraction was found to be the least toxic, the highest LC50 and LT50 values and ethyl acetate extract fraction having highest toxicity. Thus the present study supplements to our earlier report, that indicated the last aqueous extract fraction of C. asiaticum has potent antioxidant and antibacterial potentials as well as its prospective use in livestock maintenance, as it is least toxic and the ethyl acetate extract, the most toxic fraction identified here, is needed to explore for pharmaceutical importance.

Parkinsonia aculeata aqueous extract fraction: Biochemical studies in alloxan-induced diabetic rats

2007 ◽  
Vol 111 (3) ◽  
pp. 547-552 ◽  
Author(s):  
A.C.R. Leite ◽  
T.G. Araújo ◽  
B.M. Carvalho ◽  
N.H. Silva ◽  
V.L.M. Lima ◽  
...  
Keyword(s):  
Aqueous Extract ◽  
Diabetic Rats ◽  
Parkinsonia Aculeata ◽  
Biochemical Studies ◽  
Extract Fraction

Phytochemical, Antihyperglycaemic and Lipid Profile Effects of Methanol Extract Fraction of Ricinus comminus Seeds in Alloxan Induced Diabetic Male Wistar Albino

2015 ◽  
Vol 11 (1) ◽  
pp. 24-33 ◽  
Author(s):  
F.C. Nwodo Okwesili ◽  
C. Nweje-Anyalowu Paul ◽  
E. Joshua Parker ◽  
Uroko Robert Ikechukwu
Keyword(s):  
Lipid Profile ◽  
Methanol Extract ◽  
Extract Fraction

scholarly journals THE ENHANCEMENT OF COLLAGEN SYNTHESIS PROCESS ON DIABETIC WOUND BY MERREMIA MAMMOSA (LOUR.) EXTRACT FRACTION

2018 ◽  
pp. 47-50
Author(s):  
Ancah Caesarina Novi Marchianti ◽  
Mega Citra Prameswari ◽  
Elly Nurus Sakinah ◽  
Evi Umayah Ulfa
Keyword(s):  
Wound Healing ◽  
Collagen Synthesis ◽  
Negative Control ◽  
Synthesis Process ◽  
P Value ◽  
Diabetic Wound ◽  
Water Fraction ◽  
Diabetic Wound Healing ◽  
Extract Fraction ◽  
Collagen Density

Objective: This research aimed to evaluate the effect of fractionation of Merremia mammosa Lour. (Mm (Lour.)) extract on diabetic wound healing by observing collagen synthesis process and to search the most potent fraction.Methods: Wistar rats were divided into five groups (n=5), i.e., K-(negative control), K+ (positive control), K1 (ethyl acetate fraction), K2 (water fraction), and K3 (n-hexane fraction). The Mm (Lour.) was extracted with ethanol 70%, then fractionated by using three solvents which have different polarity. The rats were adapted in 7 days, then induced into diabetic by streptozotocin dose 40mg/kg body weight. The wound was made by Morton excision method. Treatment was given every two days and skin biopsy was done on day 11. Analysis of collagen density was done by photomicrograph of histopathology preparations in Masson’s trichome stained by using trinocular microscope with 400x magnification in 6 fields of view, then processed by imageJ software and analyzed by appropriate statistic tool.Result: The results of this research showed that fractionation of Mm (Lour.) extract significantly enhanced diabetic wound healing based on macroscopic (percentage of wound healing) and collagen density with p-value<0.05 when compared with negative control, especially the water fraction (p=0.000). The follow up post hoc analysis showed that there was no­ significant (p=0.989) or there was no meaningful difference in the group of water fraction when compared to positive control.Conclusion: Water fraction is the extract fraction of Mm (Lour.) which has the most significant influence on diabetic wound healing showed by enhancement of collagen synthesis.

Aqueous Porcine Pineal Extract: Inhibition of Ovulation Induced with PMSG and HCG in Immature Mice

1979 ◽  
Vol 48 (6) ◽  
pp. 1422-1428
Author(s):  
B. N. Ntunde ◽  
R. R. Hacker ◽  
R. G. Brown
Keyword(s):  
Pineal Extract

Immunomodulatory Activity of Various Fractions Derived from Physalis angulata L Extract

1992 ◽  
Vol 20 (03n04) ◽  
pp. 233-243 ◽  
Author(s):  
Yee-Shin Lin ◽  
Hsuch-Ching Chiang ◽  
Woei-Song Kan ◽  
Emily Hone ◽  
Shyh-Jen Shih ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
T Cells ◽  
Synergistic Effect ◽  
Antibody Responses ◽  
Immunomodulatory Activity ◽  
Moderate Activity ◽  
Immunomodulatory Effects ◽  
Slight Effect ◽  
Extract Fraction ◽  
Physalis Angulata

The immunomodulatory effects of Physalis angulata L. extract fraction VII (PA-VII), PA-VII-A, PA-VII-B and PA-VII-C were investigated in this study. The results showed that PA-VII and PA-VII-C strongly enhanced blastogenesis response, PA-VII-B had moderate activity, and PA-VII-A exerted only slight effect on cell proliferation. A synergistic effect was observed when the suboptimal dosage of phytohemagglutinin (PHA) or lipopolysaccharide (LPS) was added to the culture. Furthermore, PA-VII and PA-VII-C possessed stimulatory activity on B cells and less effect on T cells. The antibody responses were also augmented by PA-VII, PA-VII-B and PA-VII-C, but not by PA-VII-A. The enhancement of antibody response could be observed both in BALB/c and C3H/HeJ mice.

Control of algal growth by macrophytes and macrophyte-extracted bioactive compounds

1996 ◽  
Vol 34 (7-8) ◽  
pp. 227-235 ◽  
Author(s):  
Satoshi Nakai ◽  
Masaaki Hosomi ◽  
Mitumasa Okada ◽  
Akihiko Murakami
Keyword(s):  
Bioactive Compounds ◽  
Methanol Extract ◽  
Heterotrophic Bacteria ◽  
Myriophyllum Spicatum ◽  
Algal Growth ◽  
Selenastrum Capricornutum ◽  
Inhibitory Effects ◽  
Fractionation Process ◽  
Extract Fraction ◽  
Species Specific

Algae (Selenastrum capricornutum and Microcystis aeruginosa) were respectively assayed in a mixed-culture system using various concentrations of macrophytes obtained from Egeria densa, Cabomba caroliniana, and Myriophyllum spicatum in order to evaluate their inhibitory effects on algal growth due to possible secretion of anti-algal bioactive compounds under coexistence conditions. Based on this methodology, we also evaluated the methanol extract from macrophyte tissues, their extract fractions from a polarity-based fractionation process, and the biodegraded filtrate from the most inhibitory fraction of each macrophyte at an initial concentration which was quantitatively confirmed to produce strong inhibition of algal growth, although in this case, heterotrophic bacteria was also added to the assays. Algal assays investigating coexistence showed clear inhibitory effects which confirm the secretion theory, and also indicated the occurrence of a species-specific reaction. In these assays, and in those using the methanol extract fractions, M. spicatum demonstrated the strongest inhibitory effects on both algae. The extract fraction assays showed that in all cases the fraction containing the highest polarized compounds was the most inhibitory one, while the examined filtrates showed rapid biodegradation of all their anti-algal bioactive compounds in parallel with a substantial increase in biomass of heterotrophic bacteria.

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