Analysis of drug metabolites by gas chromatography-mass spectrometry using glass capillary columns

1975 ◽  
Vol 8 (9) ◽  
pp. 463-467 ◽  
Author(s):  
P. Christiansen
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Capillary Columns ◽  
Gas Chromatography Mass Spectrometry ◽  
Glass Capillary ◽  
Drug Metabolites ◽  
Chromatography Mass Spectrometry ◽  
Glass Capillary Columns

High-temperature gas chromatography–mass spectrometry with glass capillary columns for the screening of natural products

2002 ◽  
Vol 947 (2) ◽  
pp. 255-265 ◽  
Author(s):  
Alberto dos Santos Pereira ◽  
Silvia Albero Carbonell ◽  
Francisco Radler de Aquino Neto ◽  
Ana Claudia Fernandes do Amaral ◽  
Roderick A Barnes
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Natural Products ◽  
High Temperature ◽  
Capillary Columns ◽  
Gas Chromatography Mass Spectrometry ◽  
Glass Capillary ◽  
Chromatography Mass Spectrometry ◽  
Glass Capillary Columns ◽  
High Temperature Gas

Use of High-Resolution Open Tubular Glass Capillary Columns to Separate Acidic Metabolites in Urine

1975 ◽  
Vol 21 (7) ◽  
pp. 888-891 ◽  
Author(s):  
Brian A Knights ◽  
Mary Legendre ◽  
John L Laseter ◽  
James S Storer
Keyword(s):  
Mass Spectrometry ◽  
High Resolution ◽  
Capillary Columns ◽  
General Purpose ◽  
Gas Chromatography Mass Spectrometry ◽  
Glass Capillary ◽  
Glass Capillary Columns ◽  
Trimethylsilyl Derivatives ◽  
Derivatives Of ◽  
Urine Specimens

Abstract We used high-resolution glass capillary columns to study the trimethylsilyl derivatives of some acidic metabolites found in pooled urine specimens from control and postpartum subjects. About 30 compounds were identified by gas chromatography—mass spectrometry—computer techniques. In general, open tubular capillary columns effect better resolution of trimethylsilyl derivatives of organic acids than do conventional packed columns. GE SE-30 proved to be a good general-purpose stationary phase, whereas OV-17 offered certain advantages in resolving aromatic acid components.

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