Effects of monoamine oxidase inhibition by selegiline on concentrations of noradrenaline and monoamine metabolites in CSF of patients with Alzheimer's disease

Author(s):  
E. H. Heinonen ◽  
M. Savijärvi ◽  
M. Kotila ◽  
A. Hajba ◽  
M. Scheinin
RSC Advances ◽  
2015 ◽  
Vol 5 (86) ◽  
pp. 70395-70409 ◽  
Author(s):  
Zhi-Min Wang ◽  
Sai-Sai Xie ◽  
Xue-Mei Li ◽  
Jia-Jia Wu ◽  
Xiao-Bing Wang ◽  
...  

These 3-Schiff base-4-hydroxycoumarin derivatives were multifunctional agents with monoamine oxidase inhibition, anti-β-amyloid aggregation, metal chelation, antioxidant and neuroprotection properties against Alzheimer's disease.


MedChemComm ◽  
2014 ◽  
Vol 5 (5) ◽  
pp. 609-616 ◽  
Author(s):  
Long-Fei Pan ◽  
Xiao-Bing Wang ◽  
Sai-Sai Xie ◽  
Su-Yi Li ◽  
Ling-Yi Kong

Resveratrol derivatives were designed and synthesized as multitarget-directed agents for treating AD, and 6r was a balanced inhibitor toward all the tested targets.


1989 ◽  
Vol 46 (5) ◽  
pp. 528-536 ◽  
Author(s):  
Rainer Schulz ◽  
Karl-Heinz Antonin ◽  
Edgar Hoffmann ◽  
Maria Jedrychowski ◽  
Eric Nilsson ◽  
...  

1987 ◽  
Vol 91 (3) ◽  
pp. 293-296 ◽  
Author(s):  
T. Sunderland ◽  
P. N. Tariot ◽  
R. M. Cohen ◽  
P. A. Newhouse ◽  
A. M. Mellow ◽  
...  

2016 ◽  
Vol 14 (2) ◽  
pp. 163-165 ◽  
Author(s):  
Hamlin Emory ◽  
Neptune Mizrahi

We present clinical, electroencephalographic and low-resolution electromagnetic tomography data that support combined treatment with insulin and a monoamine oxidase inhibitor in a patient with type 1 diabetes. We suggest that brain imaging data can identify a subgroup of patients who are likely to benefit from an insulin regimen and monoamine oxidase inhibition to improve glycaemic control, cardiovascular function, normalize the circadian rhythm and restore perception of glycaemic awareness.


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