Rectal washout eliminates exfoliated malignant cells

1998 ◽  
Vol 41 (11) ◽  
pp. 1432-1434 ◽  
Author(s):  
D. C. Jenner ◽  
W. B. de Boer ◽  
G. Clarke ◽  
M. D. Levitt
Keyword(s):  
Malignant Cells ◽  
Rectal Washout ◽  
Exfoliated Malignant Cells

scholarly journals Exfoliated malignant cells at the anastomosis site in colon cancer surgery: the impact of surgical bowel occlusion and intraluminal cleaning

2011 ◽  
Vol 26 (7) ◽  
pp. 875-880 ◽  
Author(s):  
Junichi Hasegawa ◽  
Junichi Nishimura ◽  
Shunsuke Yamamoto ◽  
Youichirou Yoshida ◽  
Kazuhiro Iwase ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Surgery ◽  
Malignant Cells ◽  
Anastomosis Site ◽  
Exfoliated Malignant Cells ◽  
Colon Cancer Surgery ◽  
Bowel Occlusion ◽  
The Impact

Exfoliated malignant cells in glove and instrument washings following head and neck surgery

1996 ◽  
Vol 21 (3) ◽  
pp. 281-283 ◽  
Author(s):  
A. J. CURRAN ◽  
D. SMYTH ◽  
B. KANE ◽  
M. TONER ◽  
C. I. TIMON
Keyword(s):  
Head And Neck ◽  
Neck Surgery ◽  
Head And Neck Surgery ◽  
Malignant Cells ◽  
Exfoliated Malignant Cells

Extent of intraluminal exfoliated malignant cells during surgery for colon cancer: Differences in cell abundance ratio between laparoscopic and open surgery

2018 ◽  
Vol 12 (2) ◽  
pp. 145-149
Author(s):  
Shinichiro Kobayashi ◽  
Yusuke Inoue ◽  
Fumihiko Fujita ◽  
Shinichiro Ito ◽  
Izumi Yamaguchi ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Open Surgery ◽  
Abundance Ratio ◽  
Malignant Cells ◽  
Cell Abundance ◽  
Exfoliated Malignant Cells

scholarly journals Examination of Exfoliated Malignant Cells Collected with Intraluminal Lavage in Anterior Resection

2004 ◽  
Vol 50 (4) ◽  
pp. 373-379 ◽  
Author(s):  
MAKOTO NAKANO ◽  
NAOKI NEGAMI ◽  
HIRONOBU SENGOKU ◽  
SUMITO SUDA ◽  
MASANOBU TANAKA ◽  
...  
Keyword(s):  
Anterior Resection ◽  
Malignant Cells ◽  
Exfoliated Malignant Cells

Quantitative Assessment of Rectal Washout With Irrigation and Aspiration

2020 ◽  
Vol 14 (4) ◽  
Author(s):  
Kei Ishimaru ◽  
Mitsunori Sato ◽  
Satoshi Akita ◽  
Katsuya Watanabe ◽  
Takayasu Kawamoto ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Local Recurrence ◽  
Imaging System ◽  
Irrigation System ◽  
Meta Analysis ◽  
Rectal Washout ◽  
Cellular Debris ◽  
Anastomosis Site ◽  
Exfoliated Malignant Cells ◽  
Povidone Iodine Solution

Abstract Local recurrence of rectal cancer is defined as any evidence of relapse within the small pelvis after surgical resection of the primary tumor. After removal of a rectal tumor, necrotic cellular debris and viable exfoliated cancer cells are present in the rectal lumen; using saline or povidone-iodine solution, many surgeons perform rectal washout beyond an occlusive clamp to remove these exfoliated malignant cells, which may lead to local recurrence. A meta-analysis showed that intraoperative rectal washout at the surgical anastomosis site can reduce the risk of local recurrence after rectal cancer resection. Therefore, intraluminal lavage is useful to prevent local recurrence. Although intraoperative rectal washing is considered to be important, there is probably room for improvement on this method. We described the idea of a new transanal irrigation and aspiration system for small rectal contents. The aim of this research was to investigate the effect of a new rectal washout system using a chemiluminescent imaging system. We attempted to evaluate and compare the washout efficiency between this new system and the conventional irrigation system using a cylindrical rectum model. Our results implied that, at the same volume of solution, the irrigation–aspiration rectal washout system was more effective than the irrigation washout system. This new rectal washout system was easy to use and allowed a good washout. To the best of our knowledge, this was the first report that evaluated the efficacy of a rectal washout system using quantitative data.

Nuclear coiled bodies and the nucleolus

1994 ◽  
Vol 52 ◽  
pp. 20-21
Author(s):  
K. Brasch ◽  
J. Williams ◽  
D. Gallo ◽  
T. Lee ◽  
R. L. Ochs
Keyword(s):  
Mouse Liver ◽  
Nuclear Body ◽  
Nuclear Bodies ◽  
Model Systems ◽  
Coiled Body ◽  
Rrna Processing ◽  
Malignant Cells ◽  
Sm Proteins ◽  
Coiled Bodies ◽  
Unique Protein

Though first described in 1903 by Ramon-y-Cajal as silver-staining “accessory bodies” to nucleoli, nuclear bodies were subsequently rediscovered by electron microscopy about 30 years ago. Nuclear bodies are ubiquitous, but seem most abundant in hyperactive and malignant cells. The best studied type of nuclear body is the coiled body (CB), so termed due to characteristic morphology and content of a unique protein, p80-coilin (Fig.1). While no specific functions have as yet been assigned to CBs, they contain spliceosome snRNAs and proteins, and also the nucleolar protein fibrillarin. In addition, there is mounting evidence that CBs arise from or are generated near the nucleolus and then migrate into the nucleoplasm. This suggests that as yet undefined links may exist, between nucleolar pre-rRNA processing events and the spliceosome-associated Sm proteins in CBs.We are examining CB and nucleolar changes in three diverse model systems: (1) estrogen stimulated chick liver, (2) normal and neoplastic cells, and (3) polyploid mouse liver.

CLINICAL SYMPTOMS, BIOCHEMISTRY AND CYTOLOGY OF PLEURAL, PERITONEAL EFFUSIONS

2016 ◽  
pp. 66-71
Author(s):  
Van Mao Nguyen ◽  
Huyen Quynh Trang Pham
Keyword(s):  
Pleural Effusion ◽  
Clinical Symptoms ◽  
Cross Sectional Study ◽  
Malignant Cells ◽  
Sectional Study ◽  
Pleural Effusions ◽  
Cross Sectional ◽  
Breath Sounds ◽  
Peritoneal Effusion ◽  
Neutrophil Leukocytes

Background: The cytology and the support of clinical symptoms, biochemistry for diagnosis of the cases of effusions are very important. Objectives: - To describe some of clinical symptoms and biochemistry of effusions. - To compare the results between cytology and biochemistry by the causes of pleural, peritoneal fluids. Material & Method: A cross-sectional study to describe all of 47 patients with pleural, peritoneal effusions examinated by cytology in the Hospital of Hue University of Medicine and Pharmacy from April 2013 to January 2014. Results: In 47 cases with effusions, pleural effusion accounting for 55.32%, following peritoneal effusions 29.79% and 14.89% with both of them. The most common symptoms in patients with pleural effusions were diminished or absent tactile fremitus, dull percussion, diminished or absent breath sounds (100%), in patients with peritoneal effusions was ascites (95.24%). 100% cases with pleural effusions, 50% cases with peritoneal effusions and 80% cases with pleural and peritoneal effusions were exudates. The percentage of malignant cells in patients with pleural effusions was 26.92%, in peritoneal effusions was 28.57%, in pleural and peritoneal effusions was 42.86%. The percentage of detecting the malignant cells in patients with suspected cancer in the first test was 57.14%, in the second was 9.53% and 33.33% undetectable. Most of cases which had malignant cells and inflammatory were exudates, all of the cases which had a few cells were transudates. Besides, 7.5% cases which had high neutrophil leukocytes were transudates. Conclusion: Cytology should be carry out adding to the clinical examinations and biochemistry tests to have an exact diagnosis, especially for the malignant ones. For the case with suspected cancer, we should repeat cytology test one more time to increase the ability to detect malignant cells. Key words: Effusion, pleural effusion, peritoneal effusion, cytology, biochemistry

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