Immunolocalization of monoclonal antibody-defined extracellular matrix antigens in human brain tumors

1985 ◽  
Vol 3 (2) ◽  
pp. 181-186 ◽  
Author(s):  
Rodney D. McComb ◽  
Darell D. Bigner
1988 ◽  
Vol 69 (3) ◽  
pp. 371-374 ◽  
Author(s):  
Takafumi Nishizaki ◽  
Tetsuji Orita ◽  
Masahide Saiki ◽  
Yasuhiro Furutani ◽  
Hideo Aoki

✓ Since the development of a specific monoclonal antibody against the thymidine analogue bromodeoxyuridine (BUdR), many investigators have used intravenous infusion of BUdR to estimate the proliferative potential of human brain tumors. However, side effects such as the induction of cell mutation, latent virus promotion, or inhibition of cytodifferentiation cannot be ignored, and thus many workers hesitate to use it in patients, especially those with hepatic disease or of reproductive age. Furthermore, if BUdR remains in the deoxyribonucleic acid of tumor cells after injection, analysis of the effect of chemical and radiation therapy may not be evaluated correctly. In this report, in vitro BUdR labeling with an anti-BUdR antibody is compared with the in vivo methods described by previous authors. This method appears to be useful for determining the S-phase fraction of human brain tumor. It was more rapid, and was simple, safe, and reproducible as compared to the intravenous infusion method.


1995 ◽  
Vol 22 (5) ◽  
pp. 419-426 ◽  
Author(s):  
Enud Arbit ◽  
Nai-Kong V. Cheung ◽  
Samuel D. J. Yeh ◽  
Farhad Daghighian ◽  
Jian Ju Zhang ◽  
...  

1997 ◽  
Vol 18 (1) ◽  
pp. 7-19
Author(s):  
ALEXANDER A. PREOBRAZHENSKY ◽  
FRANCESCA ALOISI ◽  
VALERY M. BARABANOV ◽  
KARL SCHWECHHEIMER

1999 ◽  
Vol 58 (5) ◽  
pp. 430-441 ◽  
Author(s):  
SHINSUKE KATO ◽  
KENJI ISHIHARA ◽  
TAKAO SHINOZAWA ◽  
HIROYUKI YAMAGUCHI ◽  
YOSHIYA ASANO ◽  
...  

1987 ◽  
Vol 74 (2) ◽  
pp. 179-182 ◽  
Author(s):  
F. Giangaspero ◽  
C. Doglioni ◽  
M. T. Rivano ◽  
S. Pileri ◽  
J. Gerdes ◽  
...  

1985 ◽  
Vol 66 (1) ◽  
pp. 75-77 ◽  
Author(s):  
M. Motoi ◽  
T. Yoshino ◽  
K. Hayashi ◽  
S. Nose ◽  
Y. Horie ◽  
...  

1995 ◽  
Vol 87 (17) ◽  
pp. 1331-1331 ◽  
Author(s):  
F. MARTINI ◽  
M. D. MATTEI ◽  
L. IACCHERI ◽  
L. LAZZARIN ◽  
G. BARBANTI-BRODANO ◽  
...  

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