The effect of transcranial application of electric currents on free fatty acid and blood glucose levels

1967 ◽  
Vol 23 (2) ◽  
pp. 146-147
Author(s):  
F. G. Martin ◽  
W. B. Wood ◽  
E. E. Elko
1977 ◽  
Vol 232 (5) ◽  
pp. E451
Author(s):  
E Hohtola ◽  
R Hissa ◽  
S Saarela

The effects of glucagon injection on temperature regulation and some metabolic parameters were studied in the pigeon. Glucagon (100 microng/kg) always inhibited shivering and caused a fall in the oxygen consumption and body temperature of the unanesthetized pigeon at + 6 degrees C. At + 34 degrees C, the same dose of glucagon had no effect on these parameters. At 22 degrees C, glucagon produced an elevation in plasma free fatty acid (FFA) and blood glucose levels. The rise in FFA at 22 degrees C coincided with the suppression of shivering at 6 degrees C. The glucagon-mediated rise in plasma FFA, but not glucose level, was potentiated by cold ambient temperature. Adrenergic blocking agents given prior to glucagon did not abolish its effects. Phentolamine even prolonged the absence and accelerated the suppression of shivering. A dissociation in the mechanisms by which catecholamines and glucagon suppress shivering is suggested. Although mobilizing energy reserves, glucagon does not seem to be calorigenic in the pigeon at this dose. The interpretation of the changes in plasma FFA levels is discussed in relation to fuel consumption during shivering.


2017 ◽  
Vol 79 (1) ◽  
pp. 16-21
Author(s):  
Naoto Tsuda ◽  
Atsuko Kawaji ◽  
Mitsuhiro Takagi ◽  
Chika Higashi ◽  
Masaki Nakamura ◽  
...  

PEDIATRICS ◽  
1969 ◽  
Vol 43 (2) ◽  
pp. 217-225
Author(s):  
Kari O. Raivio ◽  
Kalle Österlund

In a survey of blood glucose levels in 232 erythroblastotic infants during the first 3 days of life, 12 cases of significant hypoglycemia were revealed. Most of these had a severe primary disease; the incidence of hypoglycemia was 17.8% in patients with cord hemoglobin concentrations below 10 gm per 100 ml and 1.9% in those with higher cord hemoglobin levels. The low glucose values were usually observed during the first day of life and were unassociated with recognizable symptoms. Plasma insulin levels, determined in 39 cases before age 24 hours and prior to treatment, were shown to be negatively correlated with the cord hemoglobin concentrations. Hyperinsulinemia, directly correlated with the severity of the erythroblastosis, is postulated to be the cause of the low blood glucose levels. As another consequence of the hyperinsulinemia, a depression of the plasma free fatty acid concentrations was documented. The mechanism of the hyperinsulinemia, the therapeutic and prognostic implications of the hypoglycemia, as well as the effect of the depression of free fatty acid levels on the bilirubin-binding capacity of serum are briefly discussed.


1986 ◽  
Vol 251 (1) ◽  
pp. R137-R142 ◽  
Author(s):  
H. B. John-Alder ◽  
R. M. McAllister ◽  
R. L. Terjung

The functional significance of gluconeogenesis in prolonging endurance during submaximal activity was assessed in untrained and endurance-trained rats. Gluconeogenesis was inhibited at the phosphoenolpyruvate carboxykinase reaction by 3-mercaptopicolinic acid (3-MPA). Endurance was significantly reduced by 3-MPA in untrained (-32%; P less than 0.005) and in trained rats (-26%; P less than 0.001). Metabolic correlates of fatigue were examined in trained rats. At exhaustion, 3-MPA-treated rats had only 3% of resting hepatic glycogen, 46% of resting white quadriceps glycogen, and 37% of resting blood glucose. All of these substrates were at higher levels in sham-injected controls after the same duration of running (130 min). Glycogen levels in red quadriceps, blood lactate levels, and blood glycerol levels were not different between groups. Plasma free fatty acid levels were elevated to the same extent in both groups after 90 min of activity, remained high at 130 min in controls, but had returned to resting levels in the severely hypoglycemic 3-MPA-treated rats at exhaustion. The results indicate that gluconeogenesis is important for maintaining blood glucose levels and for prolonging endurance time during submaximal activity.


Author(s):  
Venugopal Vijayakumar ◽  
Nagashree R. Shankar ◽  
Ramesh Mavathur ◽  
A. Mooventhan ◽  
Sood Anju ◽  
...  

Abstract Background There exist controversies about the health effects of coconut. Fresh coconut consumption on human health has not been studied substantially. Fresh coconut consumption is a regular part of the diet for many people in tropical countries like India, and thus there is an increasing need to understand the effects of fresh coconut on various aspects of health. Aim To compare the effects of increased saturated fatty acid (SFA) and fiber intake, provided by fresh coconut, versus monounsaturated fatty acid (MUFA) and fiber intake, provided by a combination of groundnut oil and groundnuts, on anthropometry, serum insulin, glucose levels and blood pressure in healthy adults. Materials Eighty healthy volunteers, randomized into two groups, were provided with a standardized diet along with either 100 g fresh coconut or an equivalent amount of groundnuts and groundnut oil for a period of 90 days. Assessments such as anthropometric measurements, blood pressure, blood sugar and insulin levels were performed before and after the supplementation period. Results Results of this study showed a significant reduction in fasting blood sugar (FBS) in both the groups. However, a significant reduction in body weight was observed in the coconut group, while a significant increase in diastolic pressure was observed in the groundnut group. Conclusions Results of this study suggest that fresh coconut-added diet helps reduce blood glucose levels and body weight in normal healthy individuals.


Author(s):  
Mahbuba Khatun ◽  
Md. Motiar Rahman ◽  
M. Manirujjaman ◽  
Meftah Uddin ◽  
Mst. Gulshan Ara ◽  
...  

In the recent decades, peoples concentrate more on reduced-consumption of diets containing saturated fatty acids and replace them with essential polyunsaturated ones, including omega-3 and omega-6 fatty acids, due to their promising nutritional benefits. Therefore, the production of chicken meat having lower fat compositions, and riches in pro-healthy fatty acid and other macro-and micronutrients deserves great attention in the food industry. The research aimed to characterize meat oils of two commercially available, domestic and poultry, chickens in the Northern part of Bangladesh (Rajshahi), followed by the investigation of their nutritional compositions and hypoglycemic effect in vivo. In this work, the oil was isolated from the dried meat sources by Soxhlet extractor and purified using a rotary evaporator. We subsequently characterized meat oil in terms of various parameters, such as iodine value, saponification number, unsaponifiable matter, free fatty acid (FFA) contents, peroxide value, and acid value. Besides, the nutritional parameters of chicken oil were investigated as percentages of essential fatty acids and several other micro-and macronutrients using gas-liquid chromatography and other conventional methods. Finally, Alloxan-induced Wister rats were fed with oil and chicken flesh to investigate the hypoglycemic effects. The experimental analyses show that chicken oil possesses a significant proportion of omega-3 and omega-6 fatty acid, macro-and micronutrients. Besides, oil and flesh were found to lower blood glucose levels in diabetic rats despite flesh could not significantly show hypoglycemic properties.


2017 ◽  
Vol 11 (1) ◽  
pp. 69
Author(s):  
Retno Larasati ◽  
Bambang Wirjatmadi ◽  
Merryna Adriani

The purpose of this study was to know differences in fasting blood glucose levels among both the control and treatment groups were given Trans Fatty Acid of groceries margarine and oil is heated rapidly. This research is true experimental design to study Post Test Only Control Group Design. The sample size in this study was 25 rats wistar strain males were divided into 5 groups: the first group was the control, the second group by of margarine that is heated by the content of TFA 1%, the third group by the addition palm oil, which is heated repeats to content TFA 1%, the fourth group by margarine are heated with TFA content of 2%, and the fifth group by the addition of palm oil, which is heated repeats to the TFA content of 2%. Treatment was given for 4 weeks, after the laboratory examination of fasting blood glucose at the end of the treatment. Data fasting blood glucose levels in all groups were tested by one-way ANOVA with 95% confidence level. The results showed that TFA may increase the levels of fasting blood glucose treatment groups compared with the control group, and the differences in levels of fasting blood glucose between treatment groups was not influenced by the amount of content TFA but due to different types of TFA given that of margarine and palm oil that is heated Repeat.Keywords: fasting glucose, TFA, margarine, oil heated, rats


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