Regulation in vitro of human natural killer (NK) cell activity

1981 ◽  
Vol 170 (2) ◽  
pp. 109-116 ◽  
Author(s):  
J. G. Aaskov ◽  
Debra A. Dalglish
Keyword(s):  
Natural Killer ◽  
Nk Cell ◽  
Cell Activity ◽  
Nk Cell Activity

Effects of Emitted Qi on In Vitro Natural Killer Cell Cytotoxic Activity

2001 ◽  
Vol 29 (01) ◽  
pp. 17-22 ◽  
Author(s):  
Myeong Soo Lee ◽  
Hwa Jeong Huh ◽  
Hye-Sook Jang ◽  
Chang Sub Han ◽  
Hoon Ryu ◽  
...  
Keyword(s):  
Natural Killer ◽  
Nk Cell ◽  
Killer Cell ◽  
Cell Activity ◽  
K562 Cells ◽  
Target Cells ◽  
Cell Cytotoxicity ◽  
Nk Cell Activity ◽  
Nk Cell Cytotoxicity

The present study investigated the effects of Korean Qi-therapy, ChunSoo Energy Healing, on natural killer (NK) cell cytotoxicity in vitro depending on Qi-treatment time and the types of cells treated. NK cell cytotoxicity was assayed by measuring LDH release from tumor target cells (K562 cell lines). NK activity was significantly increased by emitted-Qi treatment of 30 sec duration. Three and 5 minutes of Qi projection created the greatest increase in NK cell activity when mixtures of NK cells and K562 cells were treated (1.81 and 2.12 fold for 4 hr culture; 1.54 and 1.36 for 16 hr culture, respectively). NK cell activity increased significantly in Qi-treated K562 cells alone (1.13 fold, p < 0.05) compared to control. These results are consistent with in vivo Qi-therapy on humans and suggests that emitted-Qi has an acute stimulatory effect on NK cell activity. This study provides direct scientific support that Qi as such may positively affect human cellular immunity.

scholarly journals Augmentation of Cytolytic Activity in Murine Natural Killer Cells and Inhibition of Tumor Growth by the Ethanol Fraction of Oyster Extract

2016 ◽  
Vol 17 (1) ◽  
pp. 31-40 ◽  
Author(s):  
Kaito Sakaguchi ◽  
Ming Zhong ◽  
Saeko Kawai ◽  
Yoshio Shimizu ◽  
Eiichi Gohda
Keyword(s):  
Tumor Growth ◽  
Nk Cells ◽  
Natural Killer ◽  
Nk Cell ◽  
Cell Activity ◽  
Cytolytic Activity ◽  
Proteinase K ◽  
Nk Cell Activity

A reduced number and/or reduced activity of natural killer (NK) cells, which are important for defense against a variety of cancers and viral infections, occur under various stress conditions and in patients with various diseases. In this article, we report that the 30% to 50% ethanol precipitate of oyster extract (EPOE50) dose-dependently enhanced the activity of mouse spleen NK cells in vitro and in vivo. The activity of EPOE50 was eluted with a molecular weight of about 2000 by gel filtration and was inactivated by periodate but not by proteinase K. The activity of highly purified NK cells was also augmented by EPOE50 but not by oligodeoxyribonucleotide 1585, which mimics bacterial DNA. Administration of EPOE50 to mice stimulated splenic NK cell activity without a change in splenic NK cell populations. Although the proliferation of B16 tumor cells in vitro was slightly stimulated by EPOE50, the growth of B16 melanoma in vivo was dose-dependently suppressed by administration of EPOE50. Taken together, our results indicate that EPOE50 augmented NK cell activity and that its administration to mice inhibited tumor growth presumably through the activation of NK cells and also suggest that the active substance is a sugar-containing oligomer or polymer and is not of bacterial origin.

Neuroimmunomodulation with enkephalins: Enhancement of human natural killer (NK) cell activity in vitro

1984 ◽  
Vol 31 (3) ◽  
pp. 412-418 ◽  
Author(s):  
Robert E. Faith ◽  
Huey J. Liang ◽  
Anthony J. Murgo ◽  
Nicholas P. Plotnikoff
Keyword(s):  
Natural Killer ◽  
Nk Cell ◽  
Cell Activity ◽  
Nk Cell Activity

Interplay in Vitro Between ACTH, β-Endorphin, and Glucocorticoids in the Modulation of Spontaneous and Lymphokine-Inducible Human Natural Killer (NK) Cell Activity

1993 ◽  
Vol 7 (1) ◽  
pp. 16-28 ◽  
Author(s):  
G. Gatti ◽  
R.G. Masera ◽  
L. Pallavicini ◽  
M.L. Sartori ◽  
A. Staurenghi ◽  
...  
Keyword(s):  
Natural Killer ◽  
Nk Cell ◽  
Cell Activity ◽  
Nk Cell Activity
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