Epstein-Barr Virus early antigen titer by immunofluorescence in microplates

1978 ◽  
Vol 166 (1-4) ◽  
pp. 209-217 ◽  
Author(s):  
A. M. Favart ◽  
M. E. Lamy ◽  
D. Allemeersch ◽  
G. Burtonboy ◽  
J. Vanoverschelde
Keyword(s):  
Epstein Barr Virus ◽  
Early Antigen ◽  
Barr Virus ◽  
Epstein Barr

Inhibitory effects of 3-nitrophloroglucinecarboxylic acid derivatives on Epstein-Barr virus early antigen induction

1993 ◽  
Vol 68 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Ichiro Honda ◽  
Harukuni Tokuda ◽  
Mutsuo Kozuka ◽  
Koichi Yoneyama ◽  
Hoyoku Nishino ◽  
...  
Keyword(s):  
Epstein Barr Virus ◽  
Inhibitory Effects ◽  
Early Antigen ◽  
Barr Virus ◽  
Epstein Barr

Encephalitis in Infectious Mononucleosis: Diagnostic Considerations

PEDIATRICS ◽  
1976 ◽  
Vol 58 (6) ◽  
pp. 877-880
Author(s):  
Beverly J. Lange ◽  
Peter H. Berman ◽  
Joseph Bender ◽  
Werner Henle ◽  
John F. Hewetson
Keyword(s):  
Infectious Mononucleosis ◽  
Epstein Barr Virus ◽  
Nuclear Antigen ◽  
Diffuse Component ◽  
Early Antigen ◽  
Barr Virus ◽  
Ebv Infection ◽  
Antibody Titers ◽  
Epstein Barr ◽  
Etiologic Diagnosis

Four atypical cases of presumed infectious mononucleosis (IM) encephalitis are presented. To establish an etiologic diagnosis, Paul-Bunnell-Davidsohn heterophil titers (PBD), antibody titers to the antigens of the Epstein-Barr virus (EBV), and oropharyngeal excretion of EBV were determined. Criteria for a primary EBV infection are (1) an antiviral capsid antigen titer of 1:160 or greater, (2) the presence of antibody to the diffuse component of the early antigen, (3) absence of antibody to the nuclear antigen, and (4) excretion of the virus from the oropharynx. Three of the four cases met these criteria; of the three, one did not have a positive heterophil titer. The fourth case turned out not to be IM; there was a positive PBD heterophil, but there was no evidence of primary EBV infection. Although the PBD heterophil is usually a reliable test to diagnosis IM, it is not always present in children, and it is sometimes nonspecifically elevated. Some EBV titers can be nonspecifically elevated as well; however, the above criteria are diagnostic of primary EBV infection.

UNUSUAL PREVALENCE OF ANTIBODIES TO EPSTEIN-BARR VIRUS EARLY ANTIGEN IN ATAXIA TELANGIECTASIA

The Lancet ◽  
1977 ◽  
Vol 309 (8022) ◽  
pp. 1160 ◽  
Author(s):  
Jean Joncas ◽  
Normand Lapointe ◽  
Francine Gervais ◽  
Michele Leyritz ◽  
Adrian Wills
Keyword(s):  
Ataxia Telangiectasia ◽  
Epstein Barr Virus ◽  
Early Antigen ◽  
Barr Virus ◽  
Epstein Barr

New abietane diterpenoids from the cones of Larix kaempferi

2000 ◽  
Vol 78 (1) ◽  
pp. 31-40 ◽  
Author(s):  
Hironori Ohtsu ◽  
Reiko Tanaka ◽  
Yasuko In ◽  
Shunyo Matsunaga ◽  
Harukuni Tokuda ◽  
...  
Keyword(s):  
Epstein Barr Virus ◽  
Tumor Promoter ◽  
Larix Kaempferi ◽  
Inhibitory Effects ◽  
Early Antigen ◽  
Barr Virus ◽  
Primary Screening ◽  
Abietane Diterpenoids ◽  
Epstein Barr ◽  
Abietane Diterpenes

A new podocarpane diterpene, 7α,15-dihydroxypodocarp-8(14)-en-13-one (1) and eight new abietane diterpenes, abiet-8(14)-en-7α,13β,15,18-tetraol (2), 7α,13β,15-trihydroxyabiet-8(14)-en-18-oic acid (3), 13β,18-dihydroxyabiet-8(14)-en-7-one (4), 13β,15,18-trihydroxyabiet-8(14)-en-7-one (5), 7-oxo-13β-methoxyabiet-8(14)- en-18-oic acid (7), abiet-8(14)-en-7α,12α,13β,18-tetraol (8), 7α,12α,13β-trihydroxyabiet-8(14)-en-18-oic acid (9), and abiet-8(14)-en-7α,12α,13β,15,18-pentaol (10) were isolated from the CHCl3 extract of the cones of Larix kaempferi. Their structures were determined on the basis of chemical and spectral evidence. The inhibitory effects of compounds 1-4 and 7-9 on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA), were examined for a primary screening for anti-tumor promotors. Key words: Larix kaempferi, Pinaceae, cones, abietane, EBV-EA.

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