The release profile of a controlled release preparation of 5-aminosalicylic acid (Rowasa I®) in humans

1990 ◽  
Vol 33 (1) ◽  
pp. 21-25 ◽  
Author(s):  
Robin S. McLeod ◽  
Zane Cohen ◽  
Barbara J. Vari ◽  
Joan E. Blair ◽  
Gordon R. Greenberg
Keyword(s):  
Controlled Release ◽  
Release Profile ◽  
Aminosalicylic Acid ◽  
Release Preparation

Comparative bioavailability of 5-aminosalicylic acid from a controlled release preparation and an azo-bond preparation

2007 ◽  
Vol 8 (3) ◽  
pp. 289-294 ◽  
Author(s):  
L. A. CHRISTENSEN ◽  
J. FALLINGBORG ◽  
B. A. JACOBSEN ◽  
K. ABILDGAARD ◽  
H. H. RASMUSSEN ◽  
...  
Keyword(s):  
Controlled Release ◽  
Aminosalicylic Acid ◽  
Release Preparation ◽  
Comparative Bioavailability

Optimization Study to Develop Once-a-day Controlled Release Formulation of Metoclopramide with Predictable Design Space

1970 ◽  
Vol 1 (1) ◽  
pp. 71-76
Author(s):  
Rajesh Dubey ◽  
Udaya K. Chowdary ◽  
Venkateswarlu V.
Keyword(s):  
Controlled Release ◽  
Drug Release ◽  
Design Space ◽  
Release Kinetics ◽  
Release Profile ◽  
Release Formulation ◽  
Linear Effect ◽  
Controlled Release Formulation ◽  
The Difference ◽  
Face Centered

A controlled release formulation of metoclopramide was developed using a combination of hypromellose (HPMC) and hydrogenated castor oil (HCO). Developed formulations released the drug over 20 hr with release kinetics following Higuchi model. Compared to HCO, HPMC showed significantly higher influence in controlling the drug release at initial as well as later phase. The difference in the influence can be explained by the different swelling and erosion behaviour of the polymers. Effect of the polymers on release was optimized using a face-centered central composite design to generate a predictable design space. Statistical analysis of the drug release at various levels indicated a linear effect of the polymers’ levels on the drug release. The release profile of formulations containing the polymer levels at extremes of their ranges in design space was found to be similar to the predicted release profile

scholarly journals Controlled-Release Preparation of Indomethacin Using Calcium Alginate Gel.

1993 ◽  
Vol 16 (11) ◽  
pp. 1164-1168 ◽  
Author(s):  
Sumihiro SHIRAISHI ◽  
Teruko IMAI ◽  
Masaki OTAGIRI
Keyword(s):  
Controlled Release ◽  
Calcium Alginate ◽  
Alginate Gel ◽  
Release Preparation ◽  
Calcium Alginate Gel

New mesalamine polymeric conjugate for controlled release: Preparation, characterization and biodistribution study

2018 ◽  
Vol 111 ◽  
pp. 57-64 ◽  
Author(s):  
Aina L.A. Cesar ◽  
Fernanda A. Abrantes ◽  
Luana Farah ◽  
Rachel O. Castilho ◽  
Valbert Cardoso ◽  
...  
Keyword(s):  
Controlled Release ◽  
Biodistribution Study ◽  
Release Preparation ◽  
Polymeric Conjugate

scholarly journals 5-Aminosalicylic Acid in a Slow-Release Preparation: Bioavailability, Plasma Level, and Excretion in Humans

1982 ◽  
Vol 83 (5) ◽  
pp. 1062-1070 ◽  
Author(s):  
S.N. Rasmussen ◽  
S. Bondesen ◽  
E.F. Hvidberg ◽  
S. Honoré Hansen ◽  
Vibeke Binder ◽  
...  
Keyword(s):  
Plasma Level ◽  
Slow Release ◽  
Aminosalicylic Acid ◽  
Release Preparation ◽  
Slow Release Preparation

scholarly journals Effect of Physicochemical Properties in Water on Release Profile of Metominostrobin from Time-Controlled Release Granule

2001 ◽  
Vol 26 (3) ◽  
pp. 244-247 ◽  
Author(s):  
Shigeru TASHIMA ◽  
Shinji SHIMADA ◽  
Kohei MATSUMOTO ◽  
Reiji TAKEDA ◽  
Tomonori SHIRAISHI
Keyword(s):  
Controlled Release ◽  
Physicochemical Properties ◽  
Release Profile
Sign in / Sign up

Export Citation Format

Share Document