Role of photodynamic therapy in the management of early cancers of the upper aerodigestive tract

1986 ◽  
Vol 1 (3) ◽  
pp. 217-220 ◽  
Author(s):  
Jack L. Gluckman ◽  
Mark C. Weissler
Keyword(s):  
Photodynamic Therapy ◽  
Aerodigestive Tract ◽  
Upper Aerodigestive Tract

Photodynamic therapy in the upper aerodigestive tract. Overview and outlook

2016 ◽  
Vol 9 (11-12) ◽  
pp. 1302-1313 ◽  
Author(s):  
Veronika Volgger ◽  
Christian Stephan Betz
Keyword(s):  
Photodynamic Therapy ◽  
Aerodigestive Tract ◽  
Upper Aerodigestive Tract

Is there a role for flexible oesophagogastroscopy in upper aerodigestive tract squamous cell carcinoma?

2009 ◽  
Vol 124 (4) ◽  
pp. 417-419 ◽  
Author(s):  
T J Beech ◽  
M I Trotter ◽  
A L McDermott ◽  
W Mandal ◽  
A J Batch
Keyword(s):  
Squamous Cell Carcinoma ◽  
Head And Neck Cancer ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Patient Group ◽  
Squamous Cell ◽  
Aerodigestive Tract ◽  
Upper Aerodigestive Tract ◽  
Diagnostic Investigation

AbstractIntroduction:There is growing evidence to suggest that reflux (both laryngopharyngeal and gastroesophageal) has a role in the development of upper aerodigestive tract squamous cell carcinoma. This study discusses the role of identifying reflux in this patient group, and its prevalence.Methods:Prospective review of patients with head and neck cancer undergoing flexible oesophagogastroscopy as part of their diagnostic investigation.Results:Forty-five consecutive patients were identified. All patients were found to have evidence of oesophagitis, with 28 having oesophageal erosions and two Barrett's oesophagitis.Conclusion:Flexible oesophagogastroscopy is a useful test in patients with upper aerodigestive tract squamous cell carcinoma.

scholarly journals Photodynamic Therapy for 101 Early Cancers of the Upper Aerodigestive Tract, the Esophagus, and the Bronchi: A Single-Institution Experience

1999 ◽  
Vol 5 (3) ◽  
pp. 145-154 ◽  
Author(s):  
A. Radu ◽  
P. Grosjean ◽  
Ch. Fontolliet ◽  
G. Wagnieres ◽  
A. Woodtli ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Early Stage ◽  
Red Light ◽  
Green Light ◽  
Tracheobronchial Tree ◽  
Aerodigestive Tract ◽  
Upper Aerodigestive Tract ◽  
Photofrin Ii ◽  
Significant Difference ◽  
Radical Therapy

Cancer, when detected at an early stage, has a very good probability of being eradicated by surgery or radiotherapy. However, less aggressive treatments also tend to provide high rates of cure without the side effects of radical therapy. We report on the results of our clinical experience with photodynamic therapy (PDT) for the treatment of early carcinomas in the upper aerodigestive tract, the esophagus, and the tracheobronchial tree. Sixty-four patients with 101 squamous cell carcinomas were treated with three different photosensitizers: hematoporphyrin derivative (HPD), Photofrin II, and tetra (m-hydroxyphenyl)chlorin (mTHPC). Seventy-seven (76%) tumors showed a complete rsponse with no recurrence after a mean follow-up period of 27 months. There was no significant difference in terms of cure rates among the three dyes. However, mTHPC has a stronger phototoxicity and induces a shorter skin photosensitization than either of the other photosensitizers. There were eight major complications: three esophagotracheal fistulae after illumination with red light in the esophagus, two esophageal stenoses following 360° circumferential irradiation, and three bronchial stenoses. Illumination with the less penetrating green light and the use of a 180° or 240° windowed cylindrical light distributor render the risk of complications in the esophagus essentially impossible, without reducing the efficacy of the treatment. Therefore, PDT may be considered as a safe and effective treatment for early carcinomas of the upper aerodigestive tract, the esophagus, and the tracheobronchial tree.

Alcohol consumption in upper aerodigestive tract cancer: Role of head and neck surgeons' recommendations

Alcohol ◽  
2016 ◽  
Vol 51 ◽  
pp. 51-56 ◽  
Author(s):  
Hugo López-Pelayo ◽  
Laia Miquel ◽  
José Altamirano ◽  
José Luís Blanch ◽  
Antoni Gual ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Head And Neck ◽  
Aerodigestive Tract ◽  
Upper Aerodigestive Tract ◽  
Tract Cancer ◽  
Upper Aerodigestive Tract Cancer ◽  
Aerodigestive Tract Cancer

Photodynamic Therapy for Cancer of the Upper Aerodigestive Tract Using Tetra(m-hydroxyphenyl)chlorin

1996 ◽  
Vol 14 (5) ◽  
pp. 281-287 ◽  
Author(s):  
PIERRE GROSJEAN ◽  
JEAN-FRANÇOIS SAVARY ◽  
JÉRÔME MIZERET ◽  
GEORGES WAGNIERES ◽  
ALAIN WOODTLI ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Aerodigestive Tract ◽  
Upper Aerodigestive Tract
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