Sex recognition inDiglyphus isaea walker (Hymenoptera: Eulophidae): Role of an uncommon family of behaviorally active compounds

1996 ◽  
Vol 22 (11) ◽  
pp. 2063-2079 ◽  
Author(s):  
Valérie Finidori-Logli ◽  
Anne-Geneviève Bagnères ◽  
Dirk Erdmann ◽  
Wittko Francke ◽  
Jean-Luc Clément
Author(s):  
Xiao Zhou ◽  
Xiao-Fei Zhang ◽  
Dong-Yan Guo ◽  
Yan-Jun Yang ◽  
Lin Liu ◽  
...  

Objective: Lingzhu San (LZS) is a traditional Chinese medicine (TCM) prescription which can be effective in treating febrile seizures (FS) and has few researches on the mechanisms. In order to better guide the clinical use of LZS, we used the research ideas and methods of network pharmacology to find the potential core compounds, targets and pathways of LZS in the complex TCM system for the treatment of FS, and predict the mechanism. Materials and Methods: Databases such as BATMAN, TCMSP, TCMID, and SWISS TARGET are used to mine the active compounds and targets of LZS, and the target information of FS was obtained through GENECARDS and OMIM. Using Venny2.1.0 and Cytoscape software to locked the potential core compounds and targets of FS. The R language and ClusterProfiler software package were adopt to enrich and analyze the KEGG and GO pathways of the core targets and the biological processes and potential mechanisms of the core targets were revealed. Results: 187 active compounds and 2113 target proteins of LZS were collected. And 38 potential core compounds, 35 core targets and 775 metabolic and functional pathways were screened which involved in mediating FS. Finally, the role of the core compounds, targets and pivotal pathways of LZS regulated FS in the pathogenesis and therapeutic mechanism of FS was discussed and clarified. Conclusions: In this paper, the multi-compounds, multi-targets and multi-pathways mechanism of LZS in the treatment of FS was preliminarily revealed through the analysis of network pharmacology data, which is consistent with the principle of multi-compounds compatibility of TCM prescriptions and unified treatment of diseases from multiple angles, and it provides a new way for TCM to treat complex diseases caused by multiple factors.


1993 ◽  
Vol 24 (2) ◽  
pp. 101-116 ◽  
Author(s):  
Mark J. Snyder ◽  
Christopher Ameyaw‐Akumfi ◽  
Ernest S. Chang

MedChemComm ◽  
2016 ◽  
Vol 7 (6) ◽  
pp. 1082-1092 ◽  
Author(s):  
Shinya Fujii

Interactions between biologically active compounds and their targets often involve hydrophobic interactions, and hydrophobicity also influences the pharmacokinetic profile.


2016 ◽  
Vol 10 (1) ◽  
pp. 81-86
Author(s):  
Maria Gabriella Vecchio ◽  
Achal Gulati ◽  
Clara Minto ◽  
Giulia Lorenzoni

The role of dietary active compounds in human nutrition is an important area of investigation in the field of nutritional science. In this perspective, functional foods play a relevant role, offering a new kind of health tool that promises specific effects related to particular food components. Anise plant has a long cultural tradition in various countries all over the world, both as food and as drug. The essential oil of anise, extracted from the dry ripe fruits ofIllicium verumandPimpinella anisum, contains anethole, an active chemical compound that showed several functional properties including antimicrobial, antioxidant, hypoglycemic, hypolipidemic and oestrogenic properties.To date, studies conducted on the properties of anise, demonstrated the efficacy of the plant in the improvement of physiological condition in human and the possibility to exploit the active compounds of anise for the treatment of several chronic diseases. The aim of this review is to collect data on anise in order to evaluate its pharmacological properties.


Author(s):  
Sandra N. Jimenez-Garcia ◽  
Lina Garcia-Mier ◽  
Moises A. Vazquez-Cruz ◽  
Xochitl S. Ramirez-Gomez ◽  
Ramon G. Guevara-Gonzalez ◽  
...  

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