Definition of histamine release in human subjects and experimental animals using plasma histamine determinations in the whole individual

1979 ◽  
Vol 9 (1) ◽  
pp. 35-35 ◽  
Author(s):  
W. Lorenz ◽  
A. Doenicke ◽  
E. Neugebauer ◽  
B. Schwarz ◽  
A. Schmal ◽  
...  
Keyword(s):  
Histamine Release ◽  
Human Subjects ◽  
Plasma Histamine ◽  
Experimental Animals ◽  
Definition Of

scholarly journals From symptomatic to pre-symptomatic patient: the tide of personal genomics

2011 ◽  
Vol 10 (03) ◽  
pp. C03
Author(s):  
Marina Levina ◽  
Roswell Quinn
Keyword(s):  
Human Subjects ◽  
Genomic Data ◽  
Symptomatic Patient ◽  
Privacy Rights ◽  
Personal Genomics ◽  
Direct To Consumer ◽  
Marketing Social ◽  
Genomics Research ◽  
Definition Of ◽  
Consumer Marketing

Personal Genomics Companies are an emerging form of biotechnology startup that bring rapidly advancing whole genome technologies to a variety of commercial venues. With a combination of direct-to-consumer marketing, social media, and Web 2.0 applications these companies seek to create novel uses, including entertainment, for what is described as predictive medicine – that is the use of genetic marketers to create health forecasts that would allow individual’s healthcare to be tailored to their individual genomic data. In this brief piece, the authors use a critical cultural approach to question how this combination of genomics research, marketing, and communications technologies may alter both patient experiences and research processes. In it we argue these companies radically expand the definition of a patient by claiming all consumers are simply pre-symptomatic patients. Moreover, by placing genomic data on both the marketplace and cyberspace, personal genomic companies seek to create new avenues of research that alter how we define (and access) research agendas and human subjects. Therefore, beyond commonly discussed issues of ethics and privacy rights, Personal Genomics has the potential to alter both healthcare priorities and distribution.

scholarly journals Opinion on monoaminergic contributions to traits and temperament

2018 ◽  
Vol 373 (1744) ◽  
pp. 20170153 ◽  
Author(s):  
T. W. Robbins
Keyword(s):  
Neural Networks ◽  
Individual Differences ◽  
Social Functioning ◽  
Personality Factors ◽  
Monoamine Neurotransmitters ◽  
Neural Basis ◽  
Theme Issue ◽  
Experimental Animals ◽  
Neuroscience Research ◽  
Definition Of

This article critically reviews evidence relating temperamental traits and personality factors to the monoamine neurotransmitters, especially dopamine and serotonin. The genetic evidence is not yet considered to be conclusive and it is argued that basic neuroscience research on the neural basis of behaviour in experimental animals should be taken more into account. While questionnaire and lexical methodology including the ‘Five Factor’ theory has been informative (mostly for the traits relevant to social functioning, i.e. personality), biologically oriented approaches should be employed with more objective, theoretically grounded measures of cognition and behaviour, combined with neuroimaging and psychopharmacology, where appropriate. This strategy will enable specific functions of monoamines and other neuromodulators such as acetylcholine and neuropeptides (such as orexin) to be defined with respect to their roles in modulating activity in specific neural networks—leading to a more realistic definition of their interactive roles in complex, biologically based traits (i.e. temperament). This article is part of the theme issue ‘Diverse perspectives on diversity: multi-disciplinary approaches to taxonomies of individual differences’.

Inhibition of Histamine Release in Experimental Diabetes

1957 ◽  
Vol 191 (1) ◽  
pp. 25-28 ◽  
Author(s):  
Andres Goth ◽  
W. L. Nash ◽  
Mary Nagler ◽  
James Holman
Keyword(s):  
Histamine Release ◽  
Intravenous Injection ◽  
Experimental Diabetes ◽  
Egg White ◽  
Diabetic Rats ◽  
Plasma Histamine ◽  
Elevated Plasma ◽  
Edema Formation

Alloxan diabetic rats failed to show the characteristic edema and elevated plasma histamine levels which follow the intravenous injection of dextran or egg white. Pretreatment with insulin restored the ability of these rats to respond in a normal fashion. Insulin in normal rats promotes edema formation and histamine release induced by dextran or egg white. In contrast to these findings, neither diabetes nor insulin pretreatment exerted an influence on the response of rats to intravenously injected compound 48/80. These results suggest a hitherto unrecognized role of insulin in certain types of inflammation and histamine release.

Study of Human Driving Skill in Expected and Guided Conditions

2015 ◽  
Vol 73 (6) ◽  
Author(s):  
Amirah ‘Aisha Badrul Hisham ◽  
Mohamad Hafis Izran Ishak ◽  
Ruzairi Abdul Rahim ◽  
Nurul Hawani Idris
Keyword(s):  
Human Activities ◽  
Human Subjects ◽  
Index Formula ◽  
Crucial Issue ◽  
Machine System ◽  
Machine Operation ◽  
Driving Skill ◽  
Recent Developments ◽  
Human Skills ◽  
Definition Of

This day, Human Machine System (HMS) consider being a proven technology, which has gained an important role in various human activities. One of the most recent developments in this area is Human Adaptive Mechatronics (HAM) approach for enhancing human skills. This approach therefore is different compared to an ordinary HMS, in terms of its ability to adapt to changes in its environment and in the human changing level of skills. The crucial issue in HAM is in evaluating the human skills level on machine operation. In this paper, a skill index to quantify the performance of human drivers is studied in expected and guided conditions. The experiments are carried out on human subjects in normal driving. From this experiment, a new skill index formula is proposed based on the logical conditions and the definition of skill in HAM.

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