Serum-Vitamin-A-Bestimmungen und ihre Aussagekraft zum Vitamin-A-Status

1988 ◽  
Vol 27 (1) ◽  
pp. 57-70 ◽  
Author(s):  
Th. Gerlach ◽  
H. K. Biesalski ◽  
K. H. Bässler
2003 ◽  
Vol 6 (5) ◽  
pp. 447-452 ◽  
Author(s):  
Faruk Ahmed ◽  
Asfia Azim ◽  
Mohammad Akhtaruzzaman

AbstractAims:To investigate the prevalence of vitamin A deficiency among lactating women in a poor urban population of Bangladesh, and to examine the relationship between various factors and vitamin A status.Design:Cross-sectional study.Setting:Maternal and child health clinic in Dhaka City, Bangladesh.Subjects and methods:A total of 120 lactating women aged 17–37 years were randomly selected from women who attended a local maternal and child health clinic in Dhaka City for immunisation of their children. Various socio-economic, personal characteristics, dietary intakes of vitamin A and anthropometric data were collected. Serum retinol (vitamin A) concentration was determined as a measure of vitamin A status.Results:Of the subjects, 37% had low serum vitamin A levels (<30 μg dl−1), with 13.3% having sub-clinical vitamin A deficiency (<20 μg dl−1). Eighty-seven per cent had vitamin A intakes below the recommended dietary allowance. The lactating women who were either illiterate or received only informal education had significantly (P = 0.002) lower serum vitamin A levels compared with those who received formal education. The women whose husbands received formal education had significantly (P = 0.05) higher serum vitamin A levels than those whose husbands were either illiterate or received only informal education. The serum vitamin A levels of women in households with poor sanitation/latrine practice were significantly (P = 0.03) lower than those of women in households with good sanitation/latrine practice. The women with one child had significantly (P = 0.015) lower serum vitamin A levels than those with two or more children. Women with a lactation period of 6 months or more had significantly (P = 0.034) lower serum vitamin A levels than women with a lactation period of less than 6 months. The women who consumed less than the median vitamin A intake (274.8 μg day−1) had significantly (P = 0.01) lower serum vitamin A levels than those who consumed more than the median vitamin A intake. By multiple regression analysis, education level of the women, number of living children, duration of lactation and dietary intake of vitamin A were found to have significant independent relationships with serum vitamin A. The overall F-ratio (6.8) was highly significant (P = 0.000), the adjusted R2 was 0.16 (multiple R = 0.44).Conclusion:A significant proportion of poor, urban, lactating women in Bangladesh have vitamin A deficiency. Among the various factors, education level of the women, number of living children, duration of lactation and dietary intake of vitamin A appear to be important in influencing the vitamin A status of these women.


1991 ◽  
Vol 54 (4) ◽  
pp. 707-711 ◽  
Author(s):  
H Flores ◽  
M N Azevedo ◽  
F A Campos ◽  
M C Barreto-Lins ◽  
A A Cavalcanti ◽  
...  

2017 ◽  
Vol 8 (3) ◽  
pp. 30-34 ◽  
Author(s):  
Alakh Ram Verma ◽  
Prafulla Kumar Khodiar ◽  
Debapriya Rath ◽  
Seema Dhurandhar ◽  
Pradeep Kumar Patra

Background: Beside calorie and protein consumption micronutrients like folic acid, vitamin D and vitamin A have been postulated to play major role in intrauterine growth of neonates. Vitamin A compounds are critical for vision, reproduction, embryonic development, immune function and regulation of cell proliferation and differentiation.Aims and Objectives: To determine the relationship of maternal serum vitamin A levels with birth weight of babies.Material and Methods: Study group consisted of 58 randomly selected mothers who delivered at term small for gestational age babies (birth weight less than 2.5kg.). The control group comprises of 52 matched mothers, who delivered normal babies. Biochemical estimation of serum vitamin A was done by HPLC method using sigma reagent of all subjects.Results: Significantly high (p<0.05) number of mothers in study group had low serum vitamin A level compared to mothers in control group. There was a linear relationship between vitamin A status and mean birth weight of the babies.Conclusion: Although the low serum vitamin A level of mothers was significantly associated with intrauterine growth retardation, the exact effect of a vitamin A deficiency on the birth weight of babies remain unclear, but the finding suggests the importance of adequate vitamin A supplementation to pregnant mothers in India.Asian Journal of Medical Sciences Vol.8(3) 2017 30-34


1960 ◽  
Vol 11 (3) ◽  
pp. 439 ◽  
Author(s):  
WH Southcott ◽  
GL McClymont

Yearling Hereford steers in store condition (average weight 585 lb) were fed whole wheat grain, or equal parts whole wheat grain and cereal hay, each diet supplying an estimated 2 lb of starch equivalent per head per day. After the different rations had been fed for 20 weeks, followed by hay-grain rations for 1 week to equalize gastro-intestinal fill, the cattle fed an all-grain ration had lost an average of 1.03 lb per day and those fed a hay-grain ration had lost 0.84 lb per day. The final difference in weight was not significant. All cattle remained in good health. Serum vitamin A levels declined during the experiment to subnormal levels, particularly in the all-grain group, but clinical signs of vitamin A deficiency ware not evident. Coprophagia, hair chewing, and biting of woodwork were observed, particularly in the all-grain group. It is concluded that all-grain rations may be satisfactorily used for drought feeding of cattle.


2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Ying Liu ◽  
Ju-Jean Shaw ◽  
Harold E. Swaisgood ◽  
Jonathan C. Allen

β-Lactoglobulin is capable of binding fat-soluble compounds including vitamin A palmitate and is suggested to specifically enhance intestinal uptake of retinol. In this study, bioavailability of a vitamin-A-retinyl palmitate complex in skim milk and in water-based liquids was investigated in vitamin-A-depleted rats. First, rats were fed a vitamin-A-free pellet diet for 6 wk and were thereafter gavage-fed with vitamin A in oil, vitamin-A-β-lactoglobulin complex, vitamin A in oil + skim milk, and vitamin-A-β-lactoglobulin + skim milk for 2 wk and 42 wk. Vitamin A repletion, as judged by vitamin A accumulation in serum and liver, occurred in all the treatments. Vitamin-A-β-lactoglobulin complex treatments had statistical equivalence with oil-based vitamin A treatments. In a second experiment, vitamin-A-depleted rats were fed UHT-processed skim milk fortified with either oil-based or freeze-dried β-lactoglobulin-complexed retinyl palmitate. Liver and serum vitamin A were analyzed by HPLC to indicate vitamin A status in the rats. Results showed no significant difference in bioavailability of retinyl palmitate from milk made with either regular oil-based or β-lactoglobulin-complexed fortifiers. The vitamin-A-β-lactoglobulin complex, being water soluble, may be useful for fortification of nonfat products.


1960 ◽  
Vol 11 (3) ◽  
pp. 445 ◽  
Author(s):  
WH Southcott ◽  
GL McClymont

Hereford steers and heifers in poor store condition, and from 16 to 22 months old, were fed daily or weekly on whole wheat at the rate of 3.5 lb (estimated to supply 2.5 lb of starch equivalent) per day with the addition of 1 per cent. finely ground limestone. In one experiment of 16 weeks' duration, weights were maintained at about the same level (450 lb) in both groups. However, when the experiment terminated the cattle from the weekly fed group were livelier, had shed their winter coats to a greater extent, and showed more advanced eruption of the incisor teeth. In addition the values for haematocrit, haemoglobin, and red cell counts were significantly higher. In a second experiment over a period of 19 weeks, the average weights fell from 469 lb to 438 lb in the daily fed group and to 403 lb in the weekly fed group. The difference in liveweight was not significant. No improvement was observed in the activity or appearance of the cattle on weekly feeding on this occasion, although haematological examinations showed a trend in favour of this group. Additional experiments confirmed the practicability of weekly feeding for cattle and the relative ease with which the system could be introduced. However, weekly feeding incurred a greater risk of digestive disturbance and losses were heavier than with daily feeding. Cattle on carotene-deficient drought rations for 38 weeks showed no patent night blindness or other evidence of vitamin A deficiency, although individual serum vitamin A values fell as low as 2 µg per 100 ml.


2001 ◽  
Vol 7 (4-5) ◽  
pp. 799-804 ◽  
Author(s):  
F. Q. Siddiqui

We tested the effects of vitamin A supplementation on the antibody titre of 40 healthy volunteers [age range: 10-35 years], who had received a complete course of antirabies vaccine [5 injections over 30 days]. After determining the baseline serum vitamin A status of 80 volunteers, 20 pairs were matched for serum vitamin A level, body mass index, age, sex and socioeconomic status. One person from each pair was randomly assigned to an experimental or control group. The experimental group received vitamin A and antirabies vaccine. Controls received only the vaccine. The experimental group had significantly greater [2.1 times] serum antirabies titre than controls. This finding is an important step towards improving the economy of dosage of antirabies vaccines.


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