Loss of antibody production accompanied by chromosome loss in a cloned hybrid line secreting antibodies to sheep red blood cells

1985 ◽  
Vol 41 (1) ◽  
pp. 88-89 ◽  
Author(s):  
J. S. Nowak
1979 ◽  
Vol 9 (10) ◽  
pp. 768-776 ◽  
Author(s):  
Michael J. Taussig ◽  
José R. F. Corvalán ◽  
Richard M. Binns ◽  
Bruce Roser ◽  
Andrew Holliman

1967 ◽  
Vol 126 (2) ◽  
pp. 347-356 ◽  
Author(s):  
W. A. Robinson ◽  
J. Marbrook ◽  
E. Diener

A method for the primary stimulation and measurement of antibody production to sheep red blood cells in vitro has been described. In this system when mouse spleen cells are incubated with sheep erythrocytes large complement-dependent plaques are formed. The number and size of plaques increases from day 1 to day 3 of incubation with an average of 4.4 plaque areas per 1 x 106 cells plated at day 3. There is a linear relationship between the number of spleen cells plated and the number of plaques formed. Plaque formation is inhibited by colchicine, actinomycin D, and rabbit anti-mouse globulin. This system offers a possible means for the direct in vitro measurement of the number of cells in a population susceptible to antigenic stimulation by sheep erythrocytes.


1980 ◽  
Vol 21 (2) ◽  
pp. 291-298
Author(s):  
Veslemøy Myhruold

1984 ◽  
Vol 74 (1) ◽  
pp. 173-180 ◽  
Author(s):  
Shoji Maruyama ◽  
Masahiko Sugiura ◽  
Michio Nakazawa ◽  
Hiroko Tomiyama ◽  
Miyuki Shizawa ◽  
...  

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