Comparison of the effect of PGE2 and somatostatin on histamine stimulated14C-aminopyrine uptake and cyclic AMP formation in isolated rat gastric mucosal cells

1983 ◽  
Vol 13 (2-3) ◽  
pp. 200-206 ◽  
Author(s):  
W. Schepp ◽  
H. -K. Heim ◽  
H. -J. Ruoff
Pharmacology ◽  
1991 ◽  
Vol 42 (6) ◽  
pp. 327-332 ◽  
Author(s):  
A. Sarem-Aslani ◽  
D. Ratge ◽  
H.-H. Bigge ◽  
S. Walker ◽  
U. Klotz ◽  
...  

1985 ◽  
Vol 16 (3-4) ◽  
pp. 202-204 ◽  
Author(s):  
H. -J. Ruoff ◽  
K. Reutter ◽  
W. Schepp

1979 ◽  
Vol 237 (5) ◽  
pp. E437
Author(s):  
A Wollin ◽  
A H Soll ◽  
I M Samloff

Cyclic AMP production was studied in isolated canine fundic gastric mucosal cells. Histamine, prostaglandin E2 (PGE2), and secretin increased cyclic AMP production by unenriched mucosal cells. In separated cell fractions, histamine stimulation of cyclic AMP production correlated with the parietal cell content of the fractions. Secretin in concentrations above 1 nM stimulated cyclic AMP production, and this effect correlated with the pepsinogen content of the separated cell fractions. At concentrations above 1 microM, PGE2 stimulated cyclic AMP production; this effect was found in all separated cell fractions and was not associated with any of the available cell markers. PGE2 stimulation of cyclic AMP production was, however, negatively correlated with the parietal cell content. Thus, histamine stimulated cyclic AMP production by parietal cells and secretin stimulated production of cyclic AMP by chief cells. PGE2 stimulation of cyclic AMP production could not be localized to a single cell type but occurred primarily in nonparietal cells.


1994 ◽  
Vol 107 (4) ◽  
pp. 907-914 ◽  
Author(s):  
Lajos Nagy ◽  
Sandor Szabo ◽  
Romeo E. Morales ◽  
Mario Plebani ◽  
Joanne M. Jenkins

1994 ◽  
Vol 64 ◽  
pp. 277
Author(s):  
Masukazu Inoie ◽  
Shigeki Marubuchi ◽  
Hirotoshi Arai ◽  
Shiro Hirai

1997 ◽  
Vol 91 (3-5) ◽  
pp. 183-187 ◽  
Author(s):  
B Bódis ◽  
O Karádi ◽  
L Nagy ◽  
Cs Dohoczky ◽  
M Kolega ◽  
...  

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