The cognitive outcome of very preterm infants may be poorer than often reported: An empirical investigation of how methodological issues make a big difference

1994 ◽  
Vol 153 (12) ◽  
pp. 906-915 ◽  
Author(s):  
Dieter Wolke ◽  
Günter Ratschinski ◽  
Barbara Ohrt ◽  
Klaus Riegel
Keyword(s):  
Preterm Infants ◽  
Empirical Investigation ◽  
Cognitive Outcome ◽  
Methodological Issues ◽  
Very Preterm Infants ◽  
Very Preterm

scholarly journals 49 NEUROLOGICAL IMPAIRMENT AT ONE YEAR PREDICTS NEUROLOGICAL AND COGNITIVE OUTCOME AT EIGHT YEARS IN VERY PRETERM INFANTS

1991 ◽  
Vol 30 (6) ◽  
pp. 636-636 ◽  
Author(s):  
S C Roth ◽  
J Baudin ◽  
J Townsend ◽  
D C McCormick ◽  
A D Edwards ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Neurological Impairment ◽  
Cognitive Outcome ◽  
Very Preterm Infants ◽  
Very Preterm ◽  
One Year

scholarly journals Association between development of early cortical activity on amplitude-integrated EEG and 5-years neurodevelopmental outcome in the preterm infant

2019 ◽  
Author(s):  
Maria Feldmann ◽  
Valentin Rousson ◽  
Thi Dao Nguyen ◽  
Vera Bernet ◽  
Cornelia Hagmann ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Neurodevelopmental Outcome ◽  
Neonatal Morbidity ◽  
Population Group ◽  
Cognitive Outcome ◽  
List Type ◽  
Very Preterm Infants ◽  
Very Preterm ◽  
Preterm Born

AbstractAimTo analyse the association between early aEEG and cognitive outcome at early school-age in very preterm infants.MethodsProspective cohort study including infants with gestational age (GA) <32.0 weeks, undergoing continuous aEEG recording during first 4 days of life. Semiquantitative and quantitative (maximum/minimum amplitude) measures were averaged over the recording period. Cognitive outcome was assessed with the Kaufman-Assessment Battery for Children at 5 years of age. Uni- and multivariate logistic regressions were calculated between aEEG parameters and normal cognitive outcome (IQ≥85).ResultsAmong 118 monitored preterm children, 89 were assessed at median(IQR) corrected age of 68.6 months (65.5-71.2) [48% female, median(IQR) GA 29.9(28.2,30.9) weeks, mean(SD) birth weight 1235(363) grams]. Mean(SD) IQ was 97.8(12.7). IQ<85 occurred in 21.3 %, cerebral palsy was found in 3.4%. Despite univariate associations of total maturity scores, cycling subscores, background pattern and minimum aEEG amplitude with normal cognitive outcome none of the associations remained significant after adjustment for confounders. Socioeconomic status was identified as independent predictor of neurodevelopmental outcome.ConclusionIn this cohort of very preterm infants, early short-term aEEG was not predictive of later cognitive outcome. Further research is needed to explore how aEEG could help to inform long-term prognosis in this population group.Key notesPreterm born infants are at high risk for neurodevelopmental impairment.Early amplitude integrated electroencephalography characteristics are univariately associated with cognitive outcome at 5 years of age in preterm born children.However, socioeconomic factors and neonatal morbidity were stronger predictors of long-term neurodevelopmental outcome than early aEEG measures.

Antenatal and Postnatal Growth and 5-Year Cognitive Outcome in Very Preterm Infants

PEDIATRICS ◽  
2013 ◽  
Vol 133 (1) ◽  
pp. 63-70 ◽  
Author(s):  
Marika Leppänen ◽  
Helena Lapinleimu ◽  
Annika Lind ◽  
Jaakko Matomäki ◽  
Liisa Lehtonen ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Postnatal Growth ◽  
Cognitive Outcome ◽  
Very Preterm Infants ◽  
Very Preterm

Behaviour at 2 years of age in very preterm infants (gestational age <32 weeks)

2003 ◽  
Vol 92 (5) ◽  
pp. 1-1 ◽  
Author(s):  
GMSJ Stoelhorst ◽  
SE Martens ◽  
M Rijken ◽  
van Zwieten PHT ◽  
AH Zwinderman ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Gestational Age ◽  
Very Preterm Infants ◽  
Very Preterm
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