Effects of constant light exposure and blindness on the oxidative metabolism of selected brain areas in male rats

1977 ◽  
Vol 33 (10) ◽  
pp. 1390-1391 ◽  
Author(s):  
M. Mas ◽  
R. Alonso Solis
Keyword(s):  
Oxidative Metabolism ◽  
Light Exposure ◽  
Male Rats ◽  
Constant Light ◽  
Brain Areas

The Role of Constant Light Exposure in Various Periods of Postnatal Ontogenesis in the Development of Pathology and Mortality in Male Rats

2019 ◽  
Vol 9 (2) ◽  
pp. 141-146
Author(s):  
Yu. P. Matveeva ◽  
O. V. Zhukova ◽  
T. A. Lotosh ◽  
V. D. Yunash ◽  
A. V. Bukalev ◽  
...  
Keyword(s):  
Light Exposure ◽  
Male Rats ◽  
Postnatal Ontogenesis ◽  
Constant Light

Constant light exposure impairs immune tolerance development in mice

2017 ◽  
Vol 86 (1) ◽  
pp. 63-70 ◽  
Author(s):  
Hiromi Mizutani ◽  
Risa Tamagawa-Mineoka ◽  
Yoichi Minami ◽  
Kazuhiro Yagita ◽  
Norito Katoh
Keyword(s):  
Immune Tolerance ◽  
Light Exposure ◽  
Constant Light ◽  
Tolerance Development

INTERACTIONS OF THE PINEAL AND EXPOSURE TO CONTINUOUS LIGHT ON ORGAN WEIGHTS OF FEMALE RATS

1961 ◽  
Vol 36 (4) ◽  
pp. 617-624 ◽  
Author(s):  
Richard Jay Wurtman ◽  
Willard Roth ◽  
Mark D. Altschule ◽  
Judith J. Wurtman
Keyword(s):  
Light Exposure ◽  
Continuous Light ◽  
Female Rats ◽  
Constant Light ◽  
Ovarian Weight ◽  
Organ Weights ◽  
Bovine Pineal Extracts ◽  
Pineal Extracts ◽  
Effect Of Light

ABSTRACT Either exposure to constant light for 80 days or pinealectomy produced similar changes in the weights of the ovaries and adrenals of female rats. These were not additive when both procedures were employed. Pinealectomy did not share with light-exposure the capacity to induce uterine hypertrophy. Rats exposed to constant light for 56 days had lighter pineals than animals kept in darkness; this decrease was not affected by administration of bovine pineal extracts. The increase in ovarian weight produced in rats by exposure to light for 56 days was prevented by bovine pineal extracts, but these extracts were without effect on the uterine hypertrophy produced under the same conditions. These data suggest that the effect of light upon the weight of the ovary is mediated via the pineal.

Prolonged retention of the anorectic cobalt protoporphyrin in the hypothalamus and the resulting expression of Fos

2004 ◽  
Vol 287 (2) ◽  
pp. R465-R471 ◽  
Author(s):  
Richard A. Galbraith ◽  
Ilean Hodgdon ◽  
Michele S. Grimm ◽  
Margaret A. Vizzard
Keyword(s):  
Male Rats ◽  
Halothane Anesthesia ◽  
Short Term ◽  
Brain Areas ◽  
Duration Of Action ◽  
Prolonged Duration ◽  
Cobalt Protoporphyrin ◽  
Prolonged Retention ◽  
The Brain

The anorectic cobalt protoporphyrin (CoPP) is known to elicit short-term hypophagia and long-term weight loss through unknown mechanisms in the brains of experimental animals. The goal of this work was to determine 1) if the prolonged duration of action of CoPP is related to its prolonged retention within the brain; and 2) with the use of immunohistochemical detection of Fos, the product of the early-immediate gene c-fos, which cells are activated after exposure to CoPP. These studies were carried out in male rats after intracerebroventricular administration of CoPP, 0.4 μmol/kg body wt, given under light halothane anesthesia. Residence of CoPP in the brain was determined by residual counts in dissected brains of 57CoPP-injected rats. Fos immunoreactivity was mapped in coronal sections of rat brains 4–6 h after injection with CoPP. The results showed that 57CoPP was retained in the hypothalamus preferentially compared with the cortex of the brain and could be detected in the hypothalamus for in excess of 5 wk. Fos activation was increased by CoPP, detected predominantly in neuronal rather than glial cells, and was markedly more robust in the hypothalamus than in other brain areas. Thus CoPP remains in the hypothalamus for prolonged periods and activates Fos expression in the hypothalamus.

Temporal and spatial differences in expression of TrkB isoforms in rat retina during constant light exposure

2007 ◽  
Vol 85 (3) ◽  
pp. 346-355 ◽  
Author(s):  
Nobuharu Asai ◽  
Toshiaki Abe ◽  
Takae Saito ◽  
Hajime Sato ◽  
Sei-ichi Ishiguro ◽  
...  
Keyword(s):  
Light Exposure ◽  
Constant Light ◽  
Rat Retina ◽  
Spatial Differences ◽  
Temporal And Spatial
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