A modified regionally ischemic porcine heart preparation with eligible residual blood flows

1986 ◽  
Vol 81 (4) ◽  
pp. 384-393 ◽  
Author(s):  
H. H. Klein ◽  
K. Nebendahl ◽  
Stephanie Lindert ◽  
J. Schrader ◽  
H. Kreuzer
Keyword(s):  
Porcine Heart ◽  
Blood Flows ◽  
Heart Preparation ◽  
Residual Blood

Time-dependent Protection by Na+/H+Exchange Inhibition in a Regionally Ischemic, Reperfused Porcine Heart Preparation with Low Residual Blood Flow

1998 ◽  
Vol 30 (4) ◽  
pp. 795-801 ◽  
Author(s):  
Hermann H. Klein ◽  
Rainer M. Bohle ◽  
Sibylle Pich ◽  
Stefanie Lindert-Heimberg ◽  
Jutta Wollenweber ◽  
...  
Keyword(s):  
Blood Flow ◽  
Time Dependent ◽  
Porcine Heart ◽  
Heart Preparation ◽  
Residual Blood Flow ◽  
Residual Blood

The influence of different residual blood flows on the development of infarcts in porcine hearts

1986 ◽  
Vol 18 ◽  
pp. 9-9
Author(s):  
H KLEIN ◽  
S LINDERT ◽  
K NEBENDAHL ◽  
S PICH ◽  
H KREUZER
Keyword(s):  
Blood Flows ◽  
Residual Blood

Intramural coronary collateral flow in dogs

1990 ◽  
Vol 258 (3) ◽  
pp. H679-H682
Author(s):  
K. W. Scheel ◽  
G. Daulat ◽  
H. J. Mass ◽  
S. E. Williams
Keyword(s):  
Coronary Arteries ◽  
Flow Index ◽  
Coronary Perfusion ◽  
Collateral Flow ◽  
Retrograde Flow ◽  
Blood Flows ◽  
Before And After ◽  
Coronary Collateral Flow ◽  
Heart Preparation ◽  
The Right

The objective of this study was to determine whether intramural collaterals contribute significantly to total retrograde flow (index of collateral flow). The left circumflex, left anterior descending, right, and septal coronary arteries were separately cannulated, and blood flows through these vessels were monitored on an isolated, blood-perfused beating heart preparation. Epicardial collaterals between the borders of the circumflex and right coronary perfusion territories were cauterized, and retrograde flow from the circumflex coronary artery was determined before and after cauterization. This procedure unmasked the intramural collateral flow component to retrograde flow. By occluding and unoccluding the coronary flows from the right, septal, and left anterior descending coronary arteries during these measurements, we were able to determine their contribution to epicardial and intramural collateral flow. We found that, after cauterization, an average of 58 +/- 3.6% of the total retrograde flow remained. The septal and left anterior descending coronary arteries contributed almost equally to this retrograde flow. We concluded that, because the epicardial collaterals were cauterized, the source of retrograde flow was from intramural collaterals and constituted about one-half of the measured retrograde flow in dogs with a native collateral circulation.

COMPARISON OF ANTIHYPERTENSIVE EFFECT OF MOXONIDINE VERSUS CLONIDINE IN RENAL FAILURE PATIENTS.

2018 ◽  
Vol 6 (9) ◽  
Author(s):  
DR.MATHEW GEORGE ◽  
DR.LINCY JOSEPH ◽  
MRS.DEEPTHI MATHEW ◽  
ALISHA MARIA SHAJI ◽  
BIJI JOSEPH ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Renal Failure ◽  
Blood Flow ◽  
Blood Vessel ◽  
Blood Vessels ◽  
High Blood Pressure ◽  
Antihypertensive Effect ◽  
The Body ◽  
Ability To Work ◽  
Blood Flows

Blood pressure is the force of blood pushing against blood vessel walls as the heart pumps out blood, and high blood pressure, also called hypertension, is an increase in the amount of force that blood places on blood vessels as it moves through the body. Factors that can increase this force include higher blood volume due to extra fluid in the blood and blood vessels that are narrow, stiff, or clogged(1). High blood pressure can damage blood vessels in the kidneys, reducing their ability to work properly. When the force of blood flow is high, blood vessels stretch so blood flows more easily. Eventually, this stretching scars and weakens blood vessels throughout the body, including those in the kidneys.

Dose Response Curves for Microwave Ablation in the Cardioplegia-Arrested Porcine Heart

2005 ◽  
Vol 8 (4) ◽  
pp. E269-E274 ◽  
Author(s):  
Sydney L. Gaynor ◽  
Gregory D. Byrd ◽  
Michael D. Diodato ◽  
Yosuke Ishii ◽  
Anson M. Lee ◽  
...  
Keyword(s):  
Dose Response ◽  
Microwave Ablation ◽  
Response Curves ◽  
Porcine Heart ◽  
Dose Response Curves

Effect of cardiac rhythm on vena caval blood flows

1966 ◽  
Vol 210 (3) ◽  
pp. 505-508 ◽  
Author(s):  
AL Pinkerson ◽  
MH Luria ◽  
ED Freis
Keyword(s):  
Cardiac Rhythm ◽  
Blood Flows

Myocardial blood flow determined with krypton 85 in unanesthetized dogs

1962 ◽  
Vol 203 (1) ◽  
pp. 122-124 ◽  
Author(s):  
J. A. Herd ◽  
M. Hollenberg ◽  
G. D. Thorburn ◽  
H. H. Kopald ◽  
A. C. Barger
Keyword(s):  
Blood Flow ◽  
Coronary Artery ◽  
Myocardial Blood Flow ◽  
Exponential Function ◽  
Scintillation Detector ◽  
Left Ventricular ◽  
Blood Flows ◽  
Single Exponential Function ◽  
Single Exponential ◽  
Rapid Measurements

Serial, rapid measurements of left ventricular myocardial blood flow in trained, unanesthetized dogs have been made by injecting krypton 85 through chronically implanted coronary artery catheters and counting with an external scintillation detector. Precordial radioactivity declined as a single exponential function during the first 2 min after injection, suggesting a single rate of myocardial blood flow. Simultaneous estimations with Kr85 and blood flowmeters in acute experiments established the accuracy and reproducibility of the technique. Myocardial blood flows between 40 and 55 ml/100 g/min were observed repeatedly in three well-trained, unanesthetized dogs in the basal state.

scholarly journals Randomized Trial of Oxygen Saturation Targets during and after Resuscitation and Reversal of Ductal Flow in an Ovine Model of Meconium Aspiration and Pulmonary Hypertension

Children ◽  
2021 ◽  
Vol 8 (7) ◽  
pp. 594
Author(s):  
Amy L. Lesneski ◽  
Payam Vali ◽  
Morgan E. Hardie ◽  
Satyan Lakshminrusimha ◽  
Deepika Sankaran
Keyword(s):  
Blood Flow ◽  
Pulmonary Hypertension ◽  
Oxygen Saturation ◽  
Ductus Arteriosus ◽  
Neonatal Resuscitation ◽  
Meconium Aspiration Syndrome ◽  
Ovine Model ◽  
Neurodevelopmental Outcomes ◽  
Meconium Aspiration ◽  
Blood Flows

Neonatal resuscitation (NRP) guidelines suggest targeting 85–95% preductal SpO2 by 10 min after birth. Optimal oxygen saturation (SpO2) targets during resuscitation and in the post-resuscitation management of neonatal meconium aspiration syndrome (MAS) with persistent pulmonary hypertension (PPHN) remains uncertain. Our objective was to compare the time to reversal of ductal flow from fetal pattern (right-to-left), to left-to-right, and to evaluate pulmonary (QPA), carotid (QCA)and ductal (QDA) blood flows between standard (85–94%) and high (95–99%) SpO2 targets during and after resuscitation. Twelve lambs asphyxiated by endotracheal meconium instillation and cord occlusion to induce MAS and PPHN were resuscitated per NRP guidelines and were randomized to either standard (85–94%) or high (95–99%) SpO2 targets. Out of twelve lambs with MAS and PPHN, six each were randomized to standard and high SpO2 targets. Median [interquartile range] time to change in direction of blood flow across the ductus arteriosus from right-to-left, to left-to-right was significantly shorter with high SpO2 target (7.4 (4.4–10.8) min) compared to standard SpO2 target (31.5 (21–66.2) min, p = 0.03). QPA was significantly higher during the first 10 min after birth with higher SpO2 target. At 60 min after birth, the QPA, QCA and QDA were not different between the groups. To conclude, targeting SpO2 of 95–99% during and after resuscitation may hasten reversal of ductal flow in lambs with MAS and PPHN and transiently increase QPA but no differences were observed at 60 min. Clinical studies comparing low and high SpO2 targets assessing hemodynamics and neurodevelopmental outcomes are warranted.

Sign in / Sign up

Export Citation Format

Share Document