Time-dependent Protection by Na+/H+Exchange Inhibition in a Regionally Ischemic, Reperfused Porcine Heart Preparation with Low Residual Blood Flow

1998 ◽  
Vol 30 (4) ◽  
pp. 795-801 ◽  
Author(s):  
Hermann H. Klein ◽  
Rainer M. Bohle ◽  
Sibylle Pich ◽  
Stefanie Lindert-Heimberg ◽  
Jutta Wollenweber ◽  
...  
Keyword(s):  
Blood Flow ◽  
Time Dependent ◽  
Porcine Heart ◽  
Heart Preparation ◽  
Residual Blood Flow ◽  
Residual Blood

scholarly journals Delayed aneurysm rupture due to residual blood flow at the inflow zone of the intracranial paraclinoid internal carotid aneurysm treated with the Pipeline embolization device: Histopathological investigation

2015 ◽  
Vol 21 (6) ◽  
pp. 674-683 ◽  
Author(s):  
Hiroyuki Ikeda ◽  
Akira Ishii ◽  
Takayuki Kikuchi ◽  
Mitsushige Ando ◽  
Hideo Chihara ◽  
...  
Keyword(s):  
Blood Flow ◽  
Optic Nerve ◽  
Internal Carotid ◽  
Aneurysm Rupture ◽  
Nerve Compression ◽  
Pipeline Embolization Device ◽  
Aneurysm Wall ◽  
Residual Blood Flow ◽  
Residual Blood ◽  
Optic Nerve Compression

Cerebral aneurysm rupture is a serious complication that can occur after flow diverter (FD) placement, but the underlying mechanisms remain unclear. We encountered a case in which direct stress on the aneurysm wall caused by residual blood flow at the inflow zone near the neck during the process of thrombosis after FD placement appeared associated with aneurysm rupture. The patient was a 67-year-old woman with progressive optic nerve compression symptoms caused by a large intracranial paraclinoid internal carotid aneurysm. The patient had undergone treatment with a Pipeline embolization device (PED) with satisfactory adherence between the PED and vessel wall. Surgery was completed without complications, and optic nerve compression symptoms improved immediately after treatment. Postoperative clinical course was satisfactory, but the patient suddenly died 34 days postoperatively. Autopsy confirmed the presence of subarachnoid hemorrhage caused by rupture of the internal carotid aneurysm that had been treated with PED. Although the majority of the aneurysm lumen including the outflow zone was thrombosed, a non-thrombosed area was observed at the inflow zone. Perforation was evident in the aneurysm wall at the inflow zone near the neck, and this particular area of aneurysm wall was not covered in thrombus. Macrophage infiltration was not seen on immunohistochemical studies of the aneurysm wall near the perforation. A hemodynamically unstable period during the process of complete thrombosis of the aneurysm lumen after FD placement may be suggested, and blood pressure management and appropriate management with antiplatelet therapy may be important.

Removal of ascending aortic dissection and residual blood flow after transcatheter isolation of descending aortic dissection

2021 ◽  
Vol 27 (1) ◽  
pp. 65
Author(s):  
M. L. Gordeev ◽  
V. E. Uspenskiĭ ◽  
V. E. Rubinchik ◽  
A. N. Kotin ◽  
A. Iu. Skripnik ◽  
...  
Keyword(s):  
Blood Flow ◽  
Aortic Dissection ◽  
Residual Blood Flow ◽  
Residual Blood

A modified regionally ischemic porcine heart preparation with eligible residual blood flows

1986 ◽  
Vol 81 (4) ◽  
pp. 384-393 ◽  
Author(s):  
H. H. Klein ◽  
K. Nebendahl ◽  
Stephanie Lindert ◽  
J. Schrader ◽  
H. Kreuzer
Keyword(s):  
Porcine Heart ◽  
Blood Flows ◽  
Heart Preparation ◽  
Residual Blood

The diagnostic value of duplex ultrasound in detecting the presence and location of a stenosis in an autologous arteriovenous fistula

2019 ◽  
Vol 21 (2) ◽  
pp. 217-222
Author(s):  
Admira Ćosović ◽  
Frank GH van der Kleij ◽  
Petra MC Callenbach ◽  
Marion C Hoekstra ◽  
Rutger J Hissink ◽  
...  
Keyword(s):  
Blood Flow ◽  
Arteriovenous Fistula ◽  
Duplex Ultrasound ◽  
Diagnostic Value ◽  
Care Group ◽  
Significant Stenosis ◽  
Residual Blood Flow ◽  
Arteriovenous Fistula Stenosis ◽  
Residual Blood ◽  
Safe Approach

Objective: To determine the value of duplex ultrasound in the detection of significant (⩾50%) stenosis and the location of the stenosis in arteriovenous fistula, compared to angiography. Methods: Patients who underwent construction of an autologous arteriovenous fistula between January 2007 and December 2013 in Treant Care Group, hospital location Emmen, were included in this study. In all patients with a significantly decreased blood flow (flow <400 mL/min and/or ⩾20% decrease) measured by Transonic flowmeter before December 2016, duplex ultrasound was performed. Concordance between duplex ultrasound and angiography was analysed in all patients with a haemodynamically significant stenosis detected by duplex ultrasound. Results: In all, 63 patients had a significant decrease in blood flow leading to duplex ultrasound. In 51 (80.9%) of the 63 duplex ultrasound, a haemodynamically significant stenosis was detected. In 45 (88.2%) of these, angiography was performed, all confirming the presence of significant stenosis. In eight patients, no angiography was performed (sufficient residual blood flow (n = 7), death (n = 1)). Most stenoses were located in the venous outflow tract (75.6%). In 95.6%, a venous approach was possible during angiography. After intervention, a significant increase in blood flow was observed (from 530 mL/min to 910 mL/min (p < 0.001)). Conclusion: We show that duplex ultrasound is likely reliable to ascertain the presence of arteriovenous fistula stenosis in addition to flow criteria. Also, it provides important information to select the most effective and safe approach for cannulation. Duplex ultrasound may reduce costs and burden of diagnosing stenoses.

scholarly journals Na + /H + Exchange Inhibitor Cariporide Attenuates Cell Injury Predominantly During Ischemia and Not at Onset of Reperfusion in Porcine Hearts With Low Residual Blood Flow

Circulation ◽  
2000 ◽  
Vol 102 (16) ◽  
pp. 1977-1982 ◽  
Author(s):  
Hermann H. Klein ◽  
Sibylle Pich ◽  
Rainer M. Bohle ◽  
Stephanie Lindert-Heimberg ◽  
Klaus Nebendahl
Keyword(s):  
Blood Flow ◽  
Cell Injury ◽  
Exchange Inhibitor ◽  
Residual Blood Flow ◽  
Residual Blood

Influence of residual blood flow in the infarct-related artery on ventricular tachycardia after myocardial infarction

1992 ◽  
Vol 69 (5) ◽  
pp. 554-555 ◽  
Author(s):  
Leslie A. Saxon ◽  
C.Todd Sherman ◽  
William G. Stevenson ◽  
Lawrence A. Yeatman ◽  
Isaac Wiener
Keyword(s):  
Myocardial Infarction ◽  
Blood Flow ◽  
Ventricular Tachycardia ◽  
Infarct Related Artery ◽  
Residual Blood Flow ◽  
Residual Blood
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