Adrenergic innervation of coronary arteries and ventricular myocardium in the pig: fluorescence microscopic appearance in the normal state and after ischemia

1985 ◽  
Vol 80 (1) ◽  
pp. 18-26 ◽  
Author(s):  
S. Holmgren ◽  
T. Abrahamsson ◽  
O. Almgren
Keyword(s):  
Coronary Arteries ◽  
Normal State ◽  
Ventricular Myocardium ◽  
Adrenergic Innervation ◽  
Microscopic Appearance

Adrenergic innervation of the coronary arteries and the myocardium

1978 ◽  
Vol 100 (3) ◽  
pp. 306-316 ◽  
Author(s):  
S. Doležel ◽  
M. Gerová ◽  
J. Gero ◽  
T. Sládek ◽  
J. Vašku
Keyword(s):  
Coronary Arteries ◽  
Adrenergic Innervation

Development of the Adrenergic Innervation in the Myocardium and Coronary Arteries of the Dog

1990 ◽  
Vol 139 (2) ◽  
pp. 191-200 ◽  
Author(s):  
S. Doležel ◽  
M. Gerová ◽  
B. Hartmannová ◽  
J. Vašků
Keyword(s):  
Coronary Arteries ◽  
Adrenergic Innervation

Negative inotropic and relaxant effects of cocaine on myopathic human ventricular myocardium and epicardial coronary arteries in vitro

1993 ◽  
Vol 27 (2) ◽  
pp. 262-268 ◽  
Author(s):  
C. L Perreault ◽  
N. L Hague ◽  
K. G Morgan ◽  
P. D Allen ◽  
J. P Morgan
Keyword(s):  
Coronary Arteries ◽  
Ventricular Myocardium ◽  
Human Ventricular Myocardium

VIP and NPY in canine hearts. Distribution and effect of total and selective parasympathetic denervation

1993 ◽  
Vol 265 (1) ◽  
pp. H91-H95 ◽  
Author(s):  
F. L. Anderson ◽  
G. R. Hanson ◽  
B. Reid ◽  
M. Thorpe ◽  
A. C. Kralios
Keyword(s):  
Right Ventricle ◽  
Neuropeptide Y ◽  
Vasoactive Intestinal Peptide ◽  
Ventricular Myocardium ◽  
Adrenergic Innervation ◽  
Tissue Concentrations ◽  
Parasympathetic Ganglia ◽  
Atrioventricular Groove ◽  
Parasympathetic Neurons ◽  
Atrioventricular Nodes

The hypotheses that vasoactive intestinal peptide (VIP) is evenly distributed throughout atrial and ventricular myocardium and is present in postganglionic parasympathetic neurons in the regions of the sinoatrial and atrioventricular nodes were tested in three groups of dogs. Neuropeptide Y (NPY) tissue concentrations were determined in each group. In six sham dogs VIP and NPY concentrations were evenly distributed and were higher in atria compared with ventricles. In nine parasympathectomized dogs, VIP concentrations in sample sites from regions of the sinoatrial and atrioventricular nodes were comparable to those in sham-operated controls. In nine denervated dogs VIP concentrations were significantly decreased in three adjacent sample sites along the atrioventricular groove. In these dogs NPY concentrations were not detectable or were significantly decreased at all sample sites of both atria and ventricles. These data suggest that VIP neurons are evenly distributed in atrial and ventricular myocardium but do not originate in parasympathetic ganglia supplying the sinoatrial and atrioventricular nodes. The data also demonstrate the possible presence of extrinsic VIP neurons in the canine right ventricle and indicate that NPY may be a useful marker of myocardial adrenergic innervation.

scholarly journals A RARE COMBINATION OF NONCOMPACT MYOCARDIUM AND CORONARY DILATATION WITH TYPE 1 NEUROFIBROMATOSIS

2018 ◽  
Vol 2 (5) ◽  
pp. 159-162
Author(s):  
Олеся Ефремова ◽  
Olesya Efremova ◽  
Людмила Брегель ◽  
Lyudmila Bregel ◽  
Владимир Субботин ◽  
...  
Keyword(s):  
Left Ventricle ◽  
Coronary Arteries ◽  
Cognitive Disorders ◽  
Ventricular Myocardium ◽  
Left Ventricular ◽  
Vascular Pathology ◽  
Left Ventricular Myocardium ◽  
Rare Combination ◽  
Type 1 Neurofibromatosis

The article describes the observation of a child with a very rare combination of noncompact left ventricular myocardium and coronary dilatation in type 1 neurofibromatosis (NF 1). The first of these complications, undifferentiated cardio- myopathy, also known as noncompact myocardium, is not described in combination with NF 1 in available literature, although cases of hypertrophic cardiomyopathy in patients with NF 1 have been previously reported. Dilatation of the coronary arteries also refers to infrequent manifestations of vascular pathology against the background of neurofibro- matosis, and the combination of all three signs (NF 1, noncompact myocardium and coronary dilatation) has not yet been reported by other authors. When examining the patient, we found the characteristic signs of NF 1 (foci of “coffee” pigmentation on the skin, multiple nevuses, fibroids of the forearm, cognitive disorders), electrocardiogram features of left ventricular hypertrophy, negative T-tooth and ST-segment displacement 1 mm below the isoline in Leads V4-6, in echocardiography - pronounced trabecularity, thinning of the compact myocardium layer and a “spongy myocardium” in the region of the left ventricle apex, dilatation of the coronary arteries. With magnetic resonance imaging, signs of noncompact myocardium of the left ventricle were found, with selective coronary angiography - slowing of the coronary blood flow. The patient receives the permanent treatment for heart failure and aspirin, his condition remains stable for 4 years of follow-up

Automic innervation of dog coronary arteries

1976 ◽  
Vol 41 (1) ◽  
pp. 30-35 ◽  
Author(s):  
M. J. Denn ◽  
H. L. Stone
Keyword(s):  
Coronary Arteries ◽  
Stellate Ganglion ◽  
Coronary Vessels ◽  
Adrenergic Innervation ◽  
Cholinergic Innervation ◽  
Experimental Protocol ◽  
Cardiac Denervation ◽  
Intrinsic Nature ◽  
Great Vessels ◽  
Cervical Vagotomy

The autonomic innervation of canine coronary arteries has been examined using the Falck and Owman technique for demonstrating catecholamines and a modification of the Koelle technique for the demonstration of cholinesterase.The experimental protocol included an examination of the neural innervation of the major coronary arteries: LCC, LAD, and RCA. A consistent, relatively dense adrenergic innervation was noted. A gradient in the degree of cholinergic innervation was: LAD less than RCA less than LCC. Light microscopic examination of the hearts of dogs subjected to either cervical vagotomy or total extrinsic cardiac denervation was performed. Additional surgical procedures included removal of the left stellate ganglion and a preferentialstripping of the LCC. These studies demonstrated the intrinsic nature of parasympathetic coronary innervation. Following all surgical procedure no variations in density of cholinergic innervation were noted, indicating that these fibers are probably postganglionic parasympathetic fibers arising fromintrinsic ganglia within the ventricles. These ganglia may be located at thebase of the great vessels and send their fibers to the coronary vessels viathe septal artery.

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