Clinical significance of the resting heart rate in the assessment of autonomic function by cardiovascular reflex tests

1995 ◽  
Vol 5 (1) ◽  
pp. 61-63 ◽  
Author(s):  
S. J. Piha
2021 ◽  
Vol 9 (2) ◽  
pp. 3780-3784
Author(s):  
P.Vani ◽  
◽  
Sharan B Singh M ◽  

Introduction: Cigarette smoking is a prime risk factor for cardiovascular morbidity and mortality. Chronic smoking results in autonomic dysfunction leading to increased cardiovascular risk in smokers. The present study was planned to study the effect of smoking on the Cardiovascular Autonomic Functions among smokers. Materials and Methods: Fifty male subjects who were in the age group of 25 to 45 years. They were grouped into 25 smokers and 25 non-smokers. The participant subjects were selected among the staff members, residents and the patients from the routine OPD in SVIMS. Prior to study, they were informed about the procedure and the purpose of the study tests and written consents were obtained from them. The Cardiovascular Autonomic Function Tests were assessed by using a POLYGRAPH which was available in the department. Results and Conclusion: After applying the ‘t’-test for the difference between the two sample means, it was observed that there was a highly significant difference between the mean values of the BMI(i.e.p<0.01) and the para-sympathetic function tests among the smokers and the non – smokers(i.e.p<0.00). The Resting Heart Rate had significantly increased and the Deep breathing difference, the postural tachycardial index (Response to standing) and the Valsalva Ratio had significantly decreased in the smokers as compared to those in the non – smokers. After applying the ‘t’-test for the difference between the two sample means, it was observed that there was no significant difference between the mean values of the Postural hypotension test (i.e. p>0.05) and that there was a highly significant difference between the mean values of the Sustained handgrip test in the smokers and the non – smokers (i.e. p<0.00). KEY WORDS: Cardiovascular autonomic function tests, Smoking, Resting heart rate.


2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Meenakshi Chaswal ◽  
Raj Kapoor ◽  
Achla Batra ◽  
Savita Verma ◽  
Bhupendra S. Yadav

Alterations in the autonomic cardiovascular control have been implicated to play an important etiologic role in preeclampsia. The present study was designed to evaluate autonomic functions in preeclamptic pregnant women and compare the values with normotensive pregnant and healthy nonpregnant controls. Assessment of autonomic functions was done by cardiovascular reflex tests and by analysis of heart rate variability (HRV). Cardiovascular reflex tests included deep breathing test (DBT) and lying to standing test (LST). HRV was analyzed in both time and frequency domain for quantifying the tone of autonomic nervous system to the heart. The time domain measures included standard deviation of normal R-R intervals (SDNN) and square root of mean squared differences of successive R-R intervals (RMSSD). In the frequency domain we measured total power (TP), high frequency (HF) power, low frequency (LF) power, and LF/HF ratio. Cardiovascular reflex tests showed a significant parasympathetic deficit in preeclamptic women. Among parameters of HRV, preeclamptic group had lower values of SDNN, RMSSD, TP, HF, and LF (ms2) and higher value of LF in normalised units along with high LF/HF ratio compared to normotensive pregnant and nonpregnant controls. Furthermore, normotensive pregnant women had lower values of SDNN, TP, and LF component in both absolute power and normalised units compared to nonpregnant females. The results confirm that normal pregnancy is associated with autonomic disturbances which get exaggerated in the state of preeclampsia.


1996 ◽  
Vol 11 (3) ◽  
pp. 337-339 ◽  
Author(s):  
Angelika Nebe ◽  
Ludwig Schelosky ◽  
J�rg Wissel ◽  
Georg Ebersbach ◽  
Udo Scholz ◽  
...  

Cephalalgia ◽  
1992 ◽  
Vol 12 (6) ◽  
pp. 360-364 ◽  
Author(s):  
Rosario Martín ◽  
Cristina Ribera ◽  
Jose Manuel Moltó ◽  
Carolina Ruiz ◽  
Luz Galiano ◽  
...  

We have investigated the autonomic function of 75 patients with migraine by examining cardiovascular reflex function. The results were compared with those of 78 healthy volunteers. Measurements were made between attacks. Patients with migraine showed a smaller heart-rate response to deep breathing but a greater heart-rate response and higher blood pressure to standing when compared to controls. Migraine patients had a higher percentage of established sympathetic lesions (51% vs 17%) and severe (25% vs 5%) or atypical (24% vs 11.5%) global autonomic dysfunction. No significant differences were found among patients with migraine with aura, migraine without aura, and migraine with prolonged aura. Our findings indicate that patients with migraine have sympathetic hypofunction.


2010 ◽  
Vol 88 (12) ◽  
pp. 1166-1171 ◽  
Author(s):  
Attila Nemes ◽  
Róbert Takács ◽  
Henriette Gavallér ◽  
Tamás T. Várkonyi ◽  
Tibor Wittmann ◽  
...  

Cardiovascular autonomic dysfunction and alterations in vascular elasticity are known complications of several disorders, including diabetes mellitus, hypertension, hypercholesterolemia, aging, and chronic kidney disease. The current study was designed to test whether a relationship existed between pulse wave velocity (PWV), augmentation index (AIx), aortic elastic properties, and cardiovascular autonomic function in healthy volunteers. The study comprised 25 healthy volunteers, whose aortic strain, distensibility, and stiffness index were measured by echocardiography, whereas PWV and AIx were evaluated by Arteriograph (TensioMed, Budapest, Hungary) in all cases. Autonomic function was assessed by means of 5 standard cardiovascular reflex tests. We found that heart rate response to deep breathing, as the most reproducible cardiovascular reflex test to characterize parasympathetic function, showed low to moderate correlations with PWV (r = –0.431, p = 0.032), aortic strain (r = 0.594, p = 0.002), distensibility (r = 0.407, p = 0.043), and stiffness index (r = –0.453, p = 0.023). Valsalva ratio and autonomic neuropathy score (ANS) correlated with PWV (r = –0.557, p = 0.004 and r = –0.421, p = 0.036, respectively) and AIx (r = –0.461, p = 0.020 and r = –0.385, p = 0.057, respectively), while ANS correlated with even aortic stiffness index (r = –0.457, p = 0.022). Cardiovascular reflex tests mainly characterizing sympathetic function had no correlation with aortic stiffness parameters (p = NS for all correlations). Correlations exist between parameters characterizing aortic elasticity and parasympathetic autonomic function, as shown by standard cardiovascular reflex tests in healthy volunteers.


2006 ◽  
Vol 96 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Alexandra Jirkovská ◽  
Petr Boucek ◽  
Stephanie Wu ◽  
Jana Hosová ◽  
Robert Bém ◽  
...  

Charcot’s or neuropathic osteoarthropathy is one of the most debilitating orthopedic sequelae of diabetes mellitus. Distinguishing Charcot’s neuroarthropathy from clinically similar conditions may be challenging. The neurovascular theory postulates that Charcot’s neuroarthropathy may be secondary to sympathetic denervation of the lower-extremity vasculature. A convenient method for assessing autonomic neuropathy in patients with Charcot’s neuroarthropathy is needed. Short-term power spectral analysis (PSA) of heart rate variability (HRV), a noninvasive and quantitative method for assessing autonomic neuropathy, may be advantageous compared with the traditionally used Ewing’s cardiovascular reflex tests. However, there are limitations to the clinical use of PSA of HRV because of poor standardization. We standardized PSA of HRV and assessed autonomic neuropathy in 17 people with acute Charcot’s neuroarthropathy using PSA of HRV versus Ewing’s tests. More patients with Charcot’s neuroarthropathy were diagnosed as having autonomic neuropathy with PSA of HRV than with Ewing’s tests (94% versus 82%); however, no significant difference between the two methods was found. The results of this study suggest that PSA of HRV requires minimal patient collaboration and time expenditure compared with Ewing’s tests and may be useful in detecting autonomic neuropathy in patients with Charcot’s neuroarthropathy. (J Am Podiatr Med Assoc 96(1): 1–8, 2006)


Author(s):  
Paul Reinhart ◽  
Kendra Griffin ◽  
Christophe Micheyl

Purpose The aim of the study was to investigate changes in autonomic function, as measured by heart rate variability, in individuals with tinnitus following acoustic therapy implemented using tinnitus maskers presented via hearing aids. Method Twenty-six individuals with tinnitus and hearing impairment completed an 8-week field trial wearing hearing aids providing acoustic therapy via three tinnitus masker options set just below minimum masking level. Tinnitus handicap was measured using the Tinnitus Handicap Inventory at baseline (before starting acoustic therapy) and posttreatment (at end of 8-week trial). Resting heart rate and heart rate variability were measured using electrocardiography at baseline and posttreatment. Results There was a significant decrease in tinnitus handicap posttreatment compared to baseline. There was no change in heart rate, but there was a significant increase in heart rate variability posttreatment compared to baseline. Conclusions Acoustic therapy using tinnitus maskers delivered via hearing aids provided tinnitus relief and produced a concurrent increase in heart rate variability, suggesting a decrease in stress. Heart rate variability is a potential biomarker for tracking efficacy of acoustic therapy; however, further research is required.


2013 ◽  
Vol 9 (1) ◽  
pp. 43-50 ◽  
Author(s):  
C.L. Betros ◽  
N.M. McKeever ◽  
H.C. Manso Filho ◽  
K. Malinowski ◽  
K.H. McKeever

The chronic bradycardia seen in several species after intense exercise training may be due to autonomic mechanisms, non-autonomic mechanisms, such as increased pre-load, or a combination of the two. Thirteen, healthy, unfit Standardbred mares were split into two groups: young (age 12±1 yr; mean ± standard error, n=8) and old (age 22±1 yr, n=5) to test the hypothesis that there would be age and training related differences in resting heart rate (RHR), intrinsic heart rate (IHR), maximal heart rate (HRmax) and plasma volume (PV). Mares were trained 3 d/wk at 60% HRmax for 20 min and gradually increased to exercising 5 d/wk at 70% HRmax for 30 min and RHR, IHR, HRmax, and PV were measured prior to and after the 8 wk training period. There were no age related differences (P≯0.05) between young and old mares before (41±2 vs. 42±2 beats per minute (bpm); 86±5 vs. 80±4 bpm) or after training (35±1 vs. 34±1 bpm; 81±6 vs. 78±2 bpm) for RHR and IHR respectively. RHR was decreased (P<0.05) following training in both the young (41±2 vs. 35±1 bpm) and old mares (42±2 vs. 34±2 bpm). Training decreased IHR (P<0.05) in the young mares (86±5 vs. 81±6 bpm), but not (P≯0.05) the old mares (80±4 vs. 78±2 bpm). The young horses had a higher HRmax than the old horses (P<0.05) both before (216±5 vs. 200±4 bpm) and after training (218±3 vs. 197±5 bpm). Maximal heart rate was not altered after training (P≯0.05) in either young (216±5 vs. 218±3 bpm) or old (200±4 vs. 197±5 bpm) mares. The PV of the young mares was 15% higher before training and 32% higher after training when compared to the old mares (P<0.05). Training caused an increase in PV in young mares (+9%; P<0.05), but did not alter PV in old mares (-5%; P≯0.05). Training improved RHR in the young but not the old horses. The decrease in measured parameters in the young horses appears to be related to enhanced pre-load associated with a training-induced hypervolemia as well as changes in autonomic function.


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