scholarly journals On the permeability of the stomach mucosa for acids and some other substances

PROTOPLASMA ◽  
1940 ◽  
Vol 34 (1) ◽  
pp. 328-328
1939 ◽  
Vol 23 (2) ◽  
pp. 263-274 ◽  
Author(s):  
Torsten Teorell

1. Solutions approximately isotonic with blood of strong and weak acids, several salts, glucose, and glycine were introduced in the resting stomachs of cats. The concentration and volume changes were recorded. 2. It was found that the stomach mucosa was permeable to the majority of the ions tested. There was also a permeability in the opposite direction from the blood (mucosa) to the stomach content, particularly of alkali chlorides. Poorly permeable substances were glucose, glycine, and sodium iodate. Pure weak acids such as acetic acid penetrated very rapidly. 3. The electrolyte concentration changes in the stomach content (or gastric juice) are pictured as an exchange diffusion; for instance, the hydrogen ions of an acid are exchanged against alkali ions of the mucosa or blood. 4. It is pointed out that the concept of the mucosa as an ion permeable membrane could be used as the foundation of a "diffusion theory," which can explain the acidity and chloride variations of the gastric juice without postulating neutralizing or diluting secretions.


Author(s):  
Chul Ki Goorens ◽  
Pascal Wernaers ◽  
Joost Dewaele

AbstractLateral epicondylitis (LE) of the elbow is often treated with conservative methods. Several techniques including injections with different substances are widely performed. No standardization exists. This prospective study describes the results of the short-term follow-up of 56 patients with mean age 48 years (range: 30–68 years) treated with the Instant Tennis Elbow Cure Medical device, which fenestrates the injured tendon in a standardized way through a holder of 12 small needles. Depth and position of the needles are determined beforehand by ultrasonography. Unprepared autologous blood was injected through the holder in the tendon. Visual analog pain scale (VAS) decreased significantly in rest by 61% and during activity by 47% after 6 weeks. VAS decreased significantly in rest by 79% and during activity by 66% after 3 months. VAS did not remain significantly different after 6 months. Satisfaction rates were 71% after 6 weeks and 82% after 6 months. This suggests that the therapeutical effect sustains and in some cases increases over time. Patient Related Tennis Elbow Evaluation score ameliorated after 3 months by 71%. Comparative studies are needed to confirm this effect versus other techniques as physiotherapy, shockwave therapy, and injections with other substances.


2005 ◽  
Author(s):  
G. Marsh ◽  
A. Youk ◽  
J. Buchanich ◽  
N. Esmen ◽  
T. Hall

2014 ◽  
Vol 25 (2) ◽  
pp. 75-83
Author(s):  
Md Akmat Ali ◽  
Farida Yeasmin ◽  
MN Nag

Drug induced liver disease is a global problem. The aims of the study are to know the recreational drugs causing harmful effect on liver, epidemiology of addiction; pathophysiology and their consequences. The major findings published to date concerning different agents causing addiction and liver disease, their implications with regard to understanding disease mechanisms and their amplitude or spectrum are described. Addiction not only invites lot of sufferings to the family and the country, but also responsible for different types of liver disease including fatty liver, hepatitis and liver failure; responsible for mortality and morbidity. Among the addiction causing substances alcohol playing the main role for liver disease worldwide. Indirect effects of addiction on liver are hepatitis B, hepatitis C and their complication, mainly due to contamination of sharing needle. Majority of people in Bangladesh are life long abstainer. Excessive alcohol beverages and other substances like heroin, amphetamine are not harmless, rather they can cause serious liver diseases. There are some differences in prevalence of addiction and liver diseases among countries. Intravenous drug users are affected both directly and indirectly due to contaminated needle sharing . DOI: http://dx.doi.org/10.3329/medtoday.v25i2.17926 Medicine Today 2013 Vol.25(2): 75-83


1985 ◽  
Vol 55 ◽  
Author(s):  
Miguel F. Refojo

ABSTRACTImplants are essential for the repair of retinal detachments. The implant buckles the wall of the eye and apposes the detached retina with the choroid, thus restoring light sensitivity to the retina. The scleral buckling also relieves traction on the retina from a shrinking vitreous body. The implant materials most commonly used are solid silicone rubber and silicone sponges, but both types have some disadvantages. A poly(hydroxyethyl acrylate-co-methyl acrylate) hydrogel implant with improved properties of softness and antibiotic absorption is also available for retinal detachment surgery. Proliferative vitreoretinopathy involves various conditions of retinal detachment complicated by vitreous fibrosis, which, after vitrectomy, may be treated with intraocular injection of fluids that support the retina against the choroid. For conditions requiring a long-term implant, silicone oil although controversial is the material of choice. Many other substances have been investigated but none better has yet been found.


Author(s):  
Fatima Abdul Hussein Mejbel

 During the period from September 2016 to December 2017,135 urine samples were collected from urinary tract infection patients attending to AL-Zahraa Hospital in AL-Najaf Governorate. The present study was conducted to isolate and identify Candida spp. isolated from urinary tract infection patients by different methods including direct examination, laboratory culture, biochemical test and by modern techniques (Api Candida kit) and determine the virulence factors phenotypic to Candida spp which involved (biofilm formation,phospholipase and germ tube). The percentage of females to males was as following, female (84) 62.2 % (21) infected and male (51) 37.8% (1) infected with all age categories. The results in this study are explain that is some Candida spp. such as C. albicans, have high susceptible to eugenole follow by phenol and umbellulone. The efficiency of some chemical substances such as (eugenole,umbellulone, and phenol) was evaluated to inhibit the growth of Candida ssp as well as some virulence factors such as biofilm formation,germ tube and phospholipase,which were studied in this research. Statistically analysis results have been significance difference between the results of the substance concentrations and the concentrations of the different other substances.


1970 ◽  
Vol 6 (2) ◽  
pp. 16-24 ◽  
Author(s):  
Jorge Gelvane Tostes ◽  
Fernanda Paiva de Campos ◽  
Luís Gustavo Rodrigues Pereira

Objetivo: Traçar o perfil e estabelecer a prevalência do consumo álcool e/ou outras drogas entre os estudantes de uma faculdade de medicina do Sul de Minas Gerais. Materiais e Métodos: Os dados foram coletados com 419 alunos matriculados na faculdade no ano de 2013, a partir de questionário anônimo, o qual apresentou variáveis de idade, sexo, série do curso, uso de bebida alcoólica e drogas, frequência no ultimo mês (Julho/2013). Resultados: Constatou-se que 99% dos estudantes entrevistados já fizeram uso de bebida alcoólica ao menos uma vez na vida, sendo que 73% relataram que o ingresso na faculdade aumentou o consumo. Observou-se que o consumo é maior entre o sexo masculino. Quanto ao uso de outras drogas, 43,6% dos entrevistados relataram que fizeram uso ao menos uma vez na vida. No último mês (Julho/2013), 87,6% consumiram álcool, 23,4% tabaco, 13,4% maconha, 6,9% estimulantes, 6,2% tranquilizantes, 5,5% inalantes, 4,8% alucinógenos, 1,7% cocaína /crack, 0,2%   opiácios.  Conclusão: Os dados mostram que estudantes de medicina desta faculdade tendem a consumir drogas até duas vezes mais do que população em geral, A droga mais usada continua sendo o álcool, mas há consumo expressivo de outras substâncias como a maconha e cocaína.Palavras-chave: Álcool, Drogas, Estudantes de Medicina.ABSTRACTObjective: To describe a profile and establish the prevalence of alcohol consumption and / or other drugs among students of a medical school in southern Minas Gerais. Materials and Methods: Data were collected with 419 students enrolled in college in 2013 , from anonymous questionnaire , which presented variables of age, sex, year in the course, use of alcohol and drugs, frequency in the last month (July / 2013). Results:  99% of surveyed students were found to have already made use of alcohol at least once in their lifetime, and 73% reported entrance in college increased consumption. Higher consumption was observed among males. Regarding use of other drugs, 43.6% of the respondents have used them at least once in their life. In the previous month (July / 2013), 87.6% used alcohol, 23.4% tobacco, 13.4% marijuana, 6.9% stimulants, 6.2% tranquilizers, 5.5% inhalants 4.8% hallucinogens, 1.7% crack / cocaine, 0.2% opiates. Conclusion: The data show that college students tend to consume drugs up twice more often than the general population. The most widely used drug remains being alcohol, but there is significant use of other substances such as marijuana and cocaine.Keywords: Alcohol, Drugs, Medical Students.


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