Technetium-99m hexamethylpropylene amine oxime single-photon emission tomography of regional cerebral blood flow in insulin-dependent diabetes

1996 ◽  
Vol 23 (2) ◽  
pp. 163-168 ◽  
Author(s):  
Bart Keymeulen ◽  
Kathy de Metz ◽  
Raymond Cluydts ◽  
Axel Bossuyt ◽  
Guido Somers
1991 ◽  
Vol 158 (4) ◽  
pp. 558-562 ◽  
Author(s):  
Ken Wilson ◽  
David Bowen ◽  
Paul Francis ◽  
Philippa Tyrrell

Patients with Alzheimer disease (AD) had reduced regional cerebral blood flow (rCBF) in the posterior parietotemporal region compared with controls, as determined with technetium-99m hexamethyl propyleneamine oxime and single photon emission tomography. Central cholinergic stimulation with physostigmine produced a focal increase in rCBF in the posterior parietotemporal region in the patients with AD but not in controls.


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