O-dealkylation of resorufin ethers as an indicator of hepatic cytochrome P-450 isoenzyme induction in the cotton rat (Sigmodon hispidus): A method for monitoring environmental contamination

1991 ◽  
Vol 47 (1) ◽  
pp. 23-28 ◽  
Author(s):  
Chandikumar S. Elangbam ◽  
Charles W. Quails ◽  
Robert L. Lochmiller
Keyword(s):  
Environmental Contamination ◽  
Sigmodon Hispidus ◽  
Cotton Rat ◽  
Cytochrome P 450 ◽  
Hepatic Cytochrome

Seasonal hepatic cytochrome P-450 induction in cotton rats (Sigmodon hispidus) inhabiting petrochemical waste sites

1999 ◽  
Vol 105 (2) ◽  
pp. 191-196 ◽  
Author(s):  
R.L Lochmiller ◽  
S.T McMurry ◽  
K McBee ◽  
D.P Rafferty ◽  
J.W Lish ◽  
...  
Keyword(s):  
Sigmodon Hispidus ◽  
Petrochemical Waste ◽  
Cotton Rats ◽  
Cytochrome P 450 ◽  
Hepatic Cytochrome

Influence of Environmental Contamination on Cytochrome P-450 Mixed-Function Oxygenases in Fish: Implications for Recovery in the Wild Harbor Marsh

1978 ◽  
Vol 35 (5) ◽  
pp. 668-674 ◽  
Author(s):  
John J. Stegeman
Keyword(s):  
Environmental Contamination ◽  
Fundulus Heteroclitus ◽  
Oxygenase Activity ◽  
Marsh Site ◽  
In The Wild ◽  
Pyrene Hydroxylase ◽  
Catalytic Functions ◽  
Mixed Function Oxygenase ◽  
Cytochrome P 450 ◽  
Hepatic Cytochrome

Levels of hepatic cytochrome P-450 and the catalytic functions benzo[a]pyrene hydroxylase and aminopyrine demethylase were significantly greater in populations of mummichog, Fundulus heteroclitus, sampled from contaminated marshes than in those fish from nearby reference marshes. Aminopyrene demethylase, but not benzo[a]pyrene hydroxylase, was also elevated in fish from one of the reference marshes. The levels of cytochrome P-450 and benzo[a]pyrene hydroxylase were highest in fish from the Wild Harbor Marsh, site of the 1969 Florida spill. A correlation between size and benzo[a]pyrene hydroxylase activity was identified in some of the populations studied, although influence by this factor did not mask the population differences. The results are consistent with the hypothesis that elevated levels of mixed-function oxygenase activity in fish from Wild Harbor are the result of oil spilled 8 yr ago, and that recovery of this marsh is not yet complete. Key words: mixed-function oxygenases, benzo[a]pyrene hydroxylase, aminopyrine demethylase, cytochrome P-450, Fundulus heteroclitus, environmental contamination, oil spill recovery, petroleum

Seasonal Shifts in Thyroid Function in the Cotton Rat (Sigmodon hispidus)

1994 ◽  
Vol 75 (2) ◽  
pp. 520-528 ◽  
Author(s):  
T. E. Tomasi ◽  
D. A. Mitchell
Keyword(s):  
Thyroid Function ◽  
Sigmodon Hispidus ◽  
Cotton Rat ◽  
Seasonal Shifts
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