Molecular characteristics of water-soluble fullerene derivatives of amino acids and peptides

1996 ◽  
Vol 45 (4) ◽  
pp. 834-837 ◽  
Author(s):  
G. I. Timofeeva ◽  
V. S. Romanova ◽  
L. A. Lopanova
Keyword(s):  
Amino Acids ◽  
Water Soluble ◽  
Molecular Characteristics ◽  
Fullerene Derivatives ◽  
Derivatives Of

Influence of water-soluble derivatives of [60]fullerene on therapeutically important targets related to neurodegenerative diseases

MedChemComm ◽  
2014 ◽  
Vol 5 (11) ◽  
pp. 1664-1668 ◽  
Author(s):  
R. A. Kotelnikova ◽  
A. V. Smolina ◽  
V. V. Grigoryev ◽  
I. I. Faingold ◽  
D. V. Mischenko ◽  
...  
Keyword(s):  
Neurodegenerative Diseases ◽  
Cognitive Functioning ◽  
Water Soluble ◽  
Neuroprotective Agents ◽  
Fullerene Derivatives ◽  
Influence Of Water ◽  
Derivatives Of

Water soluble fullerene derivatives I and II were shown to behave as promising neuroprotective agents that improve cognitive functioning in animals.

scholarly journals Easy assembly of ligands for glycosidase affinity chromatography

1990 ◽  
Vol 270 (2) ◽  
pp. 539-540 ◽  
Author(s):  
R C Bernotas ◽  
B Ganem
Keyword(s):  
Amino Acids ◽  
Affinity Chromatography ◽  
Enzyme Purification ◽  
Reductive Amination ◽  
Water Soluble ◽  
High Yield ◽  
Glycosidase Inhibitors ◽  
Neutral Ph ◽  
Sepharose 4B ◽  
Derivatives Of

An improved, high-yield synthesis of the corresponding N-carboxypentyl derivatives of three iminoalditol glycosidase inhibitors has been developed for affinity chromatography enzyme purification. Reductive amination of 1-deoxynojirimycin (or its D-manno or D-galacto analogues) with methyl 5-formylvalerate and NaBH3CN at neutral pH afforted an aminoester which upon hydrolysis with aqueous 5% HCl gave the desired aminoacid in 97% overall yield. These amino acids could then be covalently attached using water-soluble carbodi-imide to 6-aminohexyl Sepharose 4B.

Automatic Column Chromatography of Ether and Water-Soluble 2,4-Dinitrophenyl-Derivatives of Amino Acids, Peptides, and Amines.

1963 ◽  
Vol 35 (1) ◽  
pp. 83-89 ◽  
Author(s):  
Leo. Kesner ◽  
Edward. Muntwyler ◽  
G. E. Griffin ◽  
Joan. Abrams
Keyword(s):  
Amino Acids ◽  
Column Chromatography ◽  
Water Soluble ◽  
Derivatives Of

scholarly journals pH-Controlled recognition of amino acids by urea derivatives of β-cyclodextrin

RSC Advances ◽  
2017 ◽  
Vol 7 (26) ◽  
pp. 15742-15746 ◽  
Author(s):  
Pawel Stepniak ◽  
Bruno Lainer ◽  
Kazimierz Chmurski ◽  
Janusz Jurczak
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Water Soluble ◽  
Urea Derivatives ◽  
Amino Acid Receptors ◽  
Derivatives Of ◽  
Ph Controlled

Water soluble amphiphilic urea-substituted β-cyclodextrins were synthesized and applied as amino acid receptors.

Potential anticonvulsants: Substituted N-benzylidene derivatives of 10-(4-aminopiperazino)-10,11-dihydrodibenzo[b,f]thiepins

1983 ◽  
Vol 48 (4) ◽  
pp. 1173-1186 ◽  
Author(s):  
Václav Bártl ◽  
Jiří Holubek ◽  
Emil Svátek ◽  
Marie Bartošová ◽  
Miroslav Protiva
Keyword(s):  
Acute Toxicity ◽  
Water Soluble ◽  
Hypotensive Activity ◽  
Anticonvulsant Effect ◽  
Maximal Electroshock ◽  
Soluble Salts ◽  
Sleeping Time ◽  
Central Depression ◽  
Derivatives Of ◽  
Electroshock Seizures

Reactions of 10-(4-aminopiperazino)-10,11-dihydrodibenzo[b,f]thiepins XIVa-XIVd with benzaldehyde, 3,4-dimethoxybenzaldehyde, 4-dimethylaminobenzaldehyde, salicylaldehyde, 3-ethoxy-4-hydroxybenzaldehyde, 2-(2-dimethylaminoethoxy)benzaldehyde, 3-(2-dimethylaminoethoxy)benzaldehyde and 3-ethoxy-4-(2-dimethylaminoethoxy)benzaldehyde afforded a series of 19 hydrazones IIIa-Xc. Some of them showed the expected anticonvulsant effect but only towards pentetrazole; antagonism of maximal electroshock seizures was not observed. In general, the products have a character of tranquillizers: in higher does they produce central depression, potentiate the thiopental sleeping time, have hypothermic action; in single cases antiamphetamine, antireserpine, antihistamine and cataleptic effects were observed. The water-soluble salts of the basic hydrazones VIIIa, VIIIc, IXc and Xc, administered parenterally, showed a rather high acute toxicity and revealed also adrenolytic and hypotensive activity.

scholarly journals Insights on Molecular Characteristics of Hydrochars by 13C-NMR and Off-Line TMAH-GC/MS and Assessment of Their Potential Use as Plant Growth Promoters

Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 1026 ◽  
Author(s):  
Laís G. Fregolente ◽  
João Vitor dos Santos ◽  
Giovanni Vinci ◽  
Alessandro Piccolo ◽  
Altair B. Moreira ◽  
...  
Keyword(s):  
Plant Growth ◽  
Phosphoric Acid ◽  
13C Nmr ◽  
Chemical Properties ◽  
Water Soluble ◽  
Molecular Characteristics ◽  
Initial Growth ◽  
Growth Promoters ◽  
Molecular Features ◽  
Potential Use

Hydrochar is a carbon-based material that can be used as soil amendment. Since the physical-chemical properties of hydrochar are mainly assigned to process parameters, we aimed at evaluating the organic fraction of different hydrochars through 13C-NMR and off-line TMAH-GC/MS. Four hydrochars produced with sugarcane bagasse, vinasse and sulfuric or phosphoric acids were analyzed to elucidate the main molecular features. Germination and initial growth of maize seedlings were assessed using hydrochar water-soluble fraction to evaluate their potential use as growth promoters. The hydrochars prepared with phosphoric acid showed larger amounts of bioavailable lignin-derived structures. Although no differences were shown about the percentage of maize seeds germination, the hydrochar produced with phosphoric acid promoted a better seedling growth. For this sample, the greatest relative percentage of benzene derivatives and phenolic compounds were associated to hormone-like effects, responsible for stimulating shoot and root elongation. The reactions parameters proved to be determinant for the organic composition of hydrochar, exerting a strict influence on molecular features and plant growth response.

scholarly journals Antioxidant Network Based on Sulfonated Polyhydroxyalkanoate and Tannic Acid Derivative

2021 ◽  
Vol 8 (1) ◽  
pp. 9
Author(s):  
Laura Brelle ◽  
Estelle Renard ◽  
Valerie Langlois
Keyword(s):  
Gallic Acid ◽  
Tannic Acid ◽  
Water Soluble ◽  
Gel Formation ◽  
Ene Reaction ◽  
Inorganic Cations ◽  
Medium Chain Length ◽  
Physically Crosslinked ◽  
The Stability ◽  
Derivatives Of

A novel generation of gels based on medium chain length poly(3-hydroxyalkanoate)s, mcl-PHAs, were developed by using ionic interactions. First, water soluble mcl-PHAs containing sulfonate groups were obtained by thiol-ene reaction in the presence of sodium-3-mercapto-1-ethanesulfonate. Anionic PHAs were physically crosslinked by divalent inorganic cations Ca2+, Ba2+, Mg2+ or by ammonium derivatives of gallic acid GA-N(CH3)3+ or tannic acid TA-N(CH3)3+. The ammonium derivatives were designed through the chemical modification of gallic acid GA or tannic acid TA with glycidyl trimethyl ammonium chloride (GTMA). The results clearly demonstrated that the formation of the networks depends on the nature of the cations. A low viscoelastic network having an elastic around 40 Pa is formed in the presence of Ca2+. Although the gel formation is not possible in the presence of GA-N(CH3)3+, the mechanical properties increased in the presence of TA-N(CH3)3+ with an elastic modulus G’ around 4200 Pa. The PHOSO3−/TA-N(CH3)3+ gels having antioxidant activity, due to the presence of tannic acid, remained stable for at least 5 months. Thus, the stability of these novel networks based on PHA encourage their use in the development of active biomaterials.

Interactions of water-soluble zinc porphyrin with amino acids

1988 ◽  
Vol 153 (4) ◽  
pp. 199-200 ◽  
Author(s):  
E. Mikros ◽  
A. Gaudemer ◽  
R. Pasternack
Keyword(s):  
Amino Acids ◽  
Water Soluble ◽  
Zinc Porphyrin ◽  
Soluble Zinc

Photo-induced DNA Cleavage by Water-soluble Cationic Fullerene Derivatives

1999 ◽  
Vol 28 (4) ◽  
pp. 321-322 ◽  
Author(s):  
Shigeori Takenaka ◽  
Kenichi Yamashita ◽  
Makoto Takagi ◽  
Taizo Hatta ◽  
Otohiko Tsuge
Keyword(s):  
Dna Cleavage ◽  
Water Soluble ◽  
Fullerene Derivatives
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