Effect of an opiate antagonist (naloxone) on the gastric acid secretory response to sham feeding, pentagastrin, and histamine in man

1982 ◽  
Vol 27 (4) ◽  
pp. 308-310 ◽  
Author(s):  
Mark Feldman ◽  
Yolanda M. Cowley
Keyword(s):  
Gastric Acid ◽  
Secretory Response ◽  
Opiate Antagonist ◽  
Sham Feeding

LATENCY OF THE GASTRIC SECRETORY RESPONSE TO SHAM FEEDING IN THE DOG

1967 ◽  
Vol 45 (4) ◽  
pp. 633-641 ◽  
Author(s):  
R. M. Preshaw
Keyword(s):  
Gastric Acid ◽  
Secretory Response ◽  
Conscious Dogs ◽  
Pepsin Secretion ◽  
Sham Feeding

In conscious dogs with gastric fistulas the latency of both the gastric acid and pepsin responses to sham feeding was about 6 min. When a background secretion was induced with various closes of hog gastrin, the latency of the acid response to sham feeding was unchanged, but the latency of the pepsin response was shortened. The peak rates of acid and pepsin secretion after sham feeding were not altered by the infusion of gastrin.

A Quantitative Study of the Gastric Secretory Response to Sham Feeding in a Human Subject

1950 ◽  
Vol 16 (1) ◽  
pp. 104-116 ◽  
Author(s):  
Henry D. Janowitz ◽  
Franklin Hollander ◽  
David Orringer ◽  
Milton H. Levy ◽  
Asher Winkelstein ◽  
...  
Keyword(s):  
Quantitative Study ◽  
Human Subject ◽  
Secretory Response ◽  
Sham Feeding

Sham Feeding Induced Gastric Acid Secretion in Patients with Caustic Induced Esophageal Stricture

Dysphagia ◽  
2021 ◽  
Author(s):  
Jimil Shah ◽  
Nikhil Bush ◽  
T. Mahesh ◽  
C. K. Nain ◽  
Rakesh Kochhar
Keyword(s):  
Acid Secretion ◽  
Gastric Acid Secretion ◽  
Gastric Acid ◽  
Esophageal Stricture ◽  
Sham Feeding

scholarly journals Acupuncture inhibits vagal gastric acid secretion stimulated by sham feeding in healthy subjects.

Gut ◽  
1994 ◽  
Vol 35 (8) ◽  
pp. 1026-1029 ◽  
Author(s):  
G Lux ◽  
J Hagel ◽  
P Backer ◽  
G Backer ◽  
R Vogl ◽  
...  
Keyword(s):  
Acid Secretion ◽  
Gastric Acid Secretion ◽  
Gastric Acid ◽  
Healthy Subjects ◽  
Sham Feeding

Plasma Gastrin and Gastric Acid Responses to Sham Feeding and Feeding in Dogs

1972 ◽  
Vol 63 (1) ◽  
pp. 51-59 ◽  
Author(s):  
Goran Nilsson ◽  
Jacques Simon ◽  
Rosalyn S. Yalow ◽  
Solomon A. Berson
Keyword(s):  
Gastric Acid ◽  
Plasma Gastrin ◽  
Sham Feeding

Impaired gastric acid secretion in mast cell-deficient mice

1990 ◽  
Vol 259 (1) ◽  
pp. G41-G47 ◽  
Author(s):  
D. J. Stechschulte ◽  
D. C. Morris ◽  
R. L. Jilka ◽  
D. J. Stechschulte ◽  
K. N. Dileepan
Keyword(s):  
Mast Cell ◽  
Acid Secretion ◽  
Gastric Acid Secretion ◽  
Gastric Acid ◽  
Parietal Cells ◽  
Secretory Response ◽  
H2 Antagonist ◽  
Significant Difference ◽  
Basal Acid ◽  
Deficient Mice

Gastric acid secretion in normal (+/+) C57B1/6J mice and congeneic, mast cell-deficient (mi/mi) C57B1/6J mice was examined. The mast cell-deficient animals had approximately 50% of the normal quantity of gastric histamine and a blunted basal acid level and secretory response. These observations were noted despite the presence of parietal cells, which were normal in number and morphology. The H2-antagonist ranitidine inhibited basal acid secretion in both groups of animals. Exogenous histamine induced a significant secretory response in normal and mast cell-deficient groups, but only the secretory response in normal animals could be blocked by the H2-antagonist. Treatment of mast cell-deficient animals with histamine for seven consecutive days before stimulation did not restore the histamine response to the normal (+/+) levels. The normal animals demonstrated an acid secretory response to pentagastrin. Mast cell-deficient mice also responded to pentagastrin, but the response was less than that observed in the normal animals, and a significant difference was not evident in all experiments. Furthermore, simultaneous injection of mast cell-deficient animals with histamine and pentagastrin did not restore pentagastrin responsiveness to normal levels, although the histamine concentration used was sufficient to raise acid secretion to basal levels of normal mice. These results support the conclusion that non-mast cell histamine only partially contributes to basal gastric acid secretion and is insufficient to facilitate full parietal cell responsiveness. Furthermore, pentagastrin requires the presence of mast cells to elicit a maximal secretory response but can use non-mast cell histamine to activate the parietal cells for acid secretion.

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