Changes in mediobasal hypothalamic dopamine and indoleamine metabolism after superior cervical ganglionectomy of rats

1996 ◽  
Vol 103 (3) ◽  
pp. 287-298 ◽  
Author(s):  
A. I. Esquifino ◽  
A. Arce ◽  
R. M. Mu�oz ◽  
M. A. Villan�a ◽  
D. P. Cardinali
1993 ◽  
Vol 10 (2) ◽  
pp. 87-93 ◽  
Author(s):  
Juan Jimenez ◽  
Carmen Osuna ◽  
Russel Reiter ◽  
Amalia Rubio ◽  
Juan Guerrero

2019 ◽  
Vol 1 (8) ◽  
pp. 811-829 ◽  
Author(s):  
Cintia Folgueira ◽  
Daniel Beiroa ◽  
Begoña Porteiro ◽  
Manon Duquenne ◽  
Emma Puighermanal ◽  
...  

1985 ◽  
Vol 87 (4) ◽  
pp. 461-463 ◽  
Author(s):  
Adriana Seilicovich ◽  
Modesto Rubio ◽  
Beatriz Duvilanski ◽  
Victor Mu�oz Maines ◽  
Valeria Rettori

2000 ◽  
Vol 279 (6) ◽  
pp. R2164-R2172 ◽  
Author(s):  
Tetsuya Ando ◽  
Rhonda F. Brown ◽  
Rodney D. Berg ◽  
Adrian J. Dunn

The potential contribution of stress-induced bacterial translocation to the activation of the hypothalamo-pituitary-adrenocortical (HPA) axis and brain biogenic amines was assessed. Mice were restrained for various periods, and brain concentrations of tryptophan, catecholamines, serotonin, and their metabolites, plasma corticosterone, and the translocation of viable bacteria from the gastrointestinal tract to the mesenteric lymph nodes, spleen, and liver were measured. Restraint induced the translocation of indigenous gram-positive bacteria in only a small proportion of animals, but translocation of gram-negative bacteria did not occur. Restraint induced short-lived increases in plasma corticosterone and brain amine metabolism, whereas bacterial translocation was slower and persisted long after the HPA axis and neurochemical responses had dissipated. When mice were infected with Salmonella typhimurium, spontaneous translocation occurred and plasma corticosterone, interleukin-6 concentrations, and brain catecholamine and indoleamine metabolism were elevated. These findings indicate that the translocation of indigenous gastrointestinal bacteria did not contribute to the HPA axis and neurochemical changes induced by restraint. However, translocation of nonindigenous S. typhimurium with or without restraint did induce HPA and neurochemical responses.


1974 ◽  
Vol 125 (585) ◽  
pp. 138-140 ◽  
Author(s):  
Judith L. Rapoport ◽  
Patricia Quinn ◽  
Nina Scribanu ◽  
Dennis L. Murphy

It has repeatedly been demonstrated that hyperactive children improve in behaviour and school functioning when treated with amphetamine, methylphenidate and, according to recent studies, imipramine (Conners, 1972). While these drugs affect catecholamine and indoleamine metabolism, there have been few studies intercorrelating the clinical and biochemical effects of these agents. A small number of untreated hyperactive children have been found to have normal urinary catecholamine and indoleamine excretion (Rapoport et al., 1970; Wender, 1971) although whole blood hydroxyindole concentrations have been reported as reduced (Coleman, 1971). In the present study, platelet serotonin content was examined before and during treatment with methylphenidate and imipramine of a group of boys with the hyperactivity syndrome.


Insects ◽  
2020 ◽  
Vol 11 (3) ◽  
pp. 155 ◽  
Author(s):  
A. S. M. Kamruzzaman ◽  
Azam Mikani ◽  
Amr A. Mohamed ◽  
Azza M. Elgendy ◽  
Makio Takeda

Although the regulation of vitellogenesis in insects has been mainly discussed in terms of ‘classical’ lipid hormones, juvenile hormone (JH), and 20-hydroxyecdysone (20E), recent data support the notion that this process must be adjusted in harmony with a nutritional input/reservoir and involvement of certain indoleamines and neuropeptides in regulation of such process. This study focuses on crosstalks among these axes, lipid hormones, monoamines, and neuropeptides in regulation of vitellogenesis in the American cockroach Periplaneta americana with novel aspects in the roles of arylalkylamine N-acetyltransferase (aaNAT), a key enzyme in indoleamine metabolism, and the enteroendocrine peptides; crustacean cardioactive peptide (CCAP) and short neuropeptide F (sNPF). Double-stranded RNA against aaNAT (dsRNAaaNAT) was injected into designated-aged females and the effects were monitored including the expressions of aaNAT itself, vitellogenin 1 and 2 (Vg1 and Vg2) and the vitellogenin receptor (VgR) mRNAs, oocyte maturation and changes in the hemolymph peptide concentrations. Effects of peptides application and 20E were also investigated. Injection of dsRNAaaNAT strongly suppressed oocyte maturation, transcription of Vg1, Vg2, VgR, and genes encoding JH acid- and farnesoate O-methyltransferases (JHAMT and FAMeT, respectively) acting in the JH biosynthetic pathway. However, it did not affect hemolymph concentrations of CCAP and sNPF. Injection of CCAP stimulated, while sNPF suppressed oocyte maturation and Vgs/VgR transcription, i.e., acting as allatomedins. Injection of CCAP promoted, while sNPF repressed ecdysteroid (20E) synthesis, particularly at the second step of Vg uptake. 20E also affected the JH biosynthetic pathway and Vg/VgR synthesis. The results revealed that on the course of vitellogenesis, JH- and 20E-mediated regulation occurs downstream to indoleamines- and peptides-mediated regulations. Intricate mutual interactions of these regulatory routes must orchestrate reproduction in this species at the highest potency.


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