Effect of hydrocortisone on duration of periods of mitotic cycle in esophageal epithelium of mice

1970 ◽  
Vol 69 (4) ◽  
pp. 448-450 ◽  
Author(s):  
M. T. Gololobova
Keyword(s):  
Mitotic Cycle ◽  
Esophageal Epithelium

The Improvement of Paclitaxel Cytotoxicity using Nanocellulose based Nature Resources

2019 ◽  
Vol 1 (1) ◽  
pp. 7
Author(s):  
R Nahrowi ◽  
A Setiawan ◽  
Noviany Noviany ◽  
I Sukmana ◽  
S D Yuwono
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Natural Resources ◽  
Cell Viability ◽  
Cancer Cells ◽  
Drug Delivery System ◽  
Target Cell ◽  
Mitotic Cycle ◽  
Potential Sources ◽  
Local Accumulation

Paclitaxel is one of the cancer drugs that often used. These drug kills cancer cells byinhibiting mitotic cycle. The efficiency of paclitaxel is increased by the use ofnanomaterials as a carrier of paclitaxel. Nanomaterials can enhance encapsulationefficiency, improve the drug release to the target cell following nanomaterialdegradation, and improve local accumulation of drug in the cell through endocytosisreceptor. Nanomaterial that often used forencapsulation of paclitaxel is a polymerderived from natural resources such as cellulose. The advantages of cellulose as acarrier of paclitaxel are nontoxic, biodegradable, and very abundant from varioussources. One of the potential sources of cellulose for drug delivery system is cassavabaggase.Keywords: Paclitaxel, encapsulation, cell viability, nanocellulose

scholarly journals Penetration of the Esophageal Epithelium by Dust Mite Antigen in Patients With Eosinophilic Esophagitis

2019 ◽  
Vol 157 (1) ◽  
pp. 255-256 ◽  
Author(s):  
Anupama Ravi ◽  
Eric V. Marietta ◽  
Debra M. Geno ◽  
Jeffrey A. Alexander ◽  
Joseph A. Murray ◽  
...  
Keyword(s):  
Eosinophilic Esophagitis ◽  
Esophageal Epithelium ◽  
Dust Mite

Regulation of cell reproduction in bud meristems of Tradescantia paludosa

1973 ◽  
Vol 51 (6) ◽  
pp. 1137-1145 ◽  
Author(s):  
Kyu-Byung Yun ◽  
J. M. Naylor
Keyword(s):  
Apical Dominance ◽  
Mitotic Cycle ◽  
Plant Cells ◽  
Central Zone ◽  
Apparent Absence ◽  
Cell Reproduction ◽  
Terminal Bud ◽  
Terminal Buds ◽  
Regulation Of Growth ◽  
Tradescantia Paludosa

The mitotic cycle can be arrested in the apical summit of vegetative terminal buds of Tradescantia paludosa by restricting the level of nitrogen or light available to the plant. Cells in this portion of the bud are much more sensitive to these stress conditions than those in the subjacent portion of the meristem. This differential response induced the establishment of a quiescent "central zone" which is distinguished from the rest of the meristem by the apparent absence of mitosis and DNA synthesis, larger nuclear volume, and a lower histone content of chromatin. These features are identical with those imposed by apical dominance in apices of inhibited lateral buds.The results support the view that competition for nutrients is an important causal factor in apical dominance. They suggest also that competition for nutrients within the terminal bud meristem is important in the regulation of growth in vegetative shoots in respones to conditions of the environment.

scholarly journals A Developmentally Regulated Gene, ASI2, Is Required for Endocycling in the Macronuclear Anlagen of Tetrahymena

2010 ◽  
Vol 9 (9) ◽  
pp. 1343-1353 ◽  
Author(s):  
Lihui Yin ◽  
Susan T. Gater ◽  
Kathleen M. Karrer
Keyword(s):  
Signal Transduction ◽  
Mitotic Cycle ◽  
Tetrahymena Thermophila ◽  
Germ Line ◽  
Ciliated Protozoa ◽  
Dna Rearrangement ◽  
Developmentally Regulated ◽  
Content Type ◽  
Molecular Events ◽  
Multicellular Organisms

ABSTRACT Ciliated protozoa contain two types of nuclei, germ line micronuclei (Mic) and transcriptionally active macronuclei (Mac). During sexual reproduction, the parental Mac degenerates and a new Mac develops from a mitotic product of the zygotic Mic. Macronuclear development involves extensive endoreplication of the genome. The present study shows that endoreplication of macronuclear DNA in Tetrahymena is an example of endocyling, a variant of the mitotic cycle with alternating S and G phases in the absence of cell division. Thus, endocycling is conserved from ciliates to multicellular organisms. The gene ASI2 in Tetrahymena thermophila encodes a putative signal transduction receptor. ASI2 is nonessential for vegetative growth, but it is upregulated during development of the new Mac. Cells that lack ASI2 in the developing Mac anlagen are arrested in endoreplication of the DNA and die. This study shows that ASI2 is also transcribed in the parental Mac early in conjugation and that transcription of ASI2 in the parental Mac supports endoreplication of the DNA during early stages of development of the Mac anlagen. Other molecular events in Mac anlage development, including developmentally regulated DNA rearrangement, occur normally in matings between ASI2 knockouts, suggesting that ASI2 specifically regulates endocycling in Tetrahymena.

Circadian rhythm of cell proliferation in the mouse esophageal epithelium

1983 ◽  
Vol 96 (3) ◽  
pp. 1327-1328
Author(s):  
A. V. Timofeev ◽  
Yu. A. Romanov ◽  
V. P. Rybakov
Keyword(s):  
Cell Proliferation ◽  
Circadian Rhythm ◽  
Esophageal Epithelium
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