scholarly journals The stimulatory effect by insulin on the incorporation of32P radioactive inorganic phosphate into intracellular inorganic phosphate, adenine nucleotides and guanine nucleotides of the intact isolated rat diaphragm

Diabetologia ◽  
1969 ◽  
Vol 5 (2) ◽  
pp. 79-87 ◽  
Author(s):  
O. Walaas ◽  
E. Walaas ◽  
A. N. Wick
Keyword(s):  
Inorganic Phosphate ◽  
Adenine Nucleotides ◽  
Guanine Nucleotides ◽  
Rat Diaphragm ◽  
Isolated Rat

THE EFFECT OF PHENETHYLBIGUANIDE UPON THE METABOLISM OF THE ISOLATED RAT DIAPHRAGM

1959 ◽  
Vol 37 (7) ◽  
pp. 881-886 ◽  
Author(s):  
N. Forbath ◽  
D. W. Clarke
Keyword(s):  
Lactic Acid ◽  
Carbohydrate Metabolism ◽  
Incubation Medium ◽  
Inorganic Phosphate ◽  
Free Sugar ◽  
Rat Diaphragm ◽  
Isolated Rat

Some of the effects of phenethylbiguanide (DBI) upon carbohydrate metabolism in the isolated rat diaphragm have been studied. The addition of this compound to an incubation medium stimulates the uptake of sugars, the breakdown of glycogen, and the output of lactic acid and inorganic phosphate. Free sugar does not accumulate in the diaphragm treated with DBI.

THE EFFECT OF PHENETHYLBIGUANIDE UPON THE METABOLISM OF THE ISOLATED RAT DIAPHRAGM

1959 ◽  
Vol 37 (1) ◽  
pp. 881-886
Author(s):  
N. Forbath ◽  
D. W. Clarke
Keyword(s):  
Lactic Acid ◽  
Carbohydrate Metabolism ◽  
Incubation Medium ◽  
Inorganic Phosphate ◽  
Free Sugar ◽  
Rat Diaphragm ◽  
Isolated Rat

Some of the effects of phenethylbiguanide (DBI) upon carbohydrate metabolism in the isolated rat diaphragm have been studied. The addition of this compound to an incubation medium stimulates the uptake of sugars, the breakdown of glycogen, and the output of lactic acid and inorganic phosphate. Free sugar does not accumulate in the diaphragm treated with DBI.

SENSITIVITY OF THE RAT DIAPHRAGM TO GROWTH HORMONE.

1967 ◽  
Vol 54 (4) ◽  
pp. 645-662 ◽  
Author(s):  
Å. Hjalmarson ◽  
K. Ahrén
Keyword(s):  
Growth Hormone ◽  
Inhibitory Effect ◽  
Rat Diaphragm ◽  
Intracellular Accumulation ◽  
Slight Effect ◽  
Kidney Capsule ◽  
Muscle Tissues ◽  
Hypophysectomized Rats ◽  
Isolated Rat

ABSTRACT The effect of growth hormone (GH) in vitro on the rate of intracellular accumulation of the non-utilizable amino acid α-aminoisobutyric acid (AIB) was studied in the intact rat diaphragm preparation. Bovine or ovine GH (25 μg/ml incubation medium) markedly stimulated the accumulation of AIB-14C by diaphragms from hypophysectomized rats, while there was no or only a very slight effect on diaphragms from normal rats. In diaphragms from rats with the pituitary gland autotransplanted to the kidney capsule GH in vitro stimulated the accumulation of AIB-14C significantly more than in diaphragms from normal rats but significantly less than in diaphragms from hypophysectomized rats. Injections of GH intramuscularly for 4 days to hypophysectomized rats made the diaphragms from these rats less sensitive or completely insensitive to GH in vitro. These results indicate strongly that the relative insensitivity to GH in vitro of diaphragms from normal rats is due to the fact that the muscle tissues from these rats has been exposed to the endogenously secreted GH. The results show that GH can influence the accumulation of AIB-14C in the isolated rat diaphragm in two different ways giving an acute or »stimulatory« effect and a late or »inhibitory« effect, and that it seems to be a time-relationship between these two effects of the hormone.

scholarly journals PHOSPHATE METABOLISM OF THE ISOLATED RAT DIAPHRAGM

1951 ◽  
Vol 189 (1) ◽  
pp. 59-63
Author(s):  
Niels. Haugaard ◽  
Julian B. Marsh ◽  
William C. Stadie
Keyword(s):  
Phosphate Metabolism ◽  
Rat Diaphragm ◽  
Isolated Rat

scholarly journals THE EFFECT OF GROWTH HORMONE ON GLUCOSE UPTAKE BY THE ISOLATED RAT DIAPHRAGM

1952 ◽  
Vol 197 (1) ◽  
pp. 151-166 ◽  
Author(s):  
C.R. Park ◽  
David H. Brown ◽  
Marvin. Cornblath ◽  
William H. Daughaday ◽  
M.E. Krahl
Keyword(s):  
Growth Hormone ◽  
Glucose Uptake ◽  
Rat Diaphragm ◽  
Isolated Rat
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